ChemicalBook > CAS DataBase List > (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

Product Name
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
CAS No.
105812-81-5
Chemical Name
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
Synonyms
PAROXOL;(-)-Paroxol;[(3S,4S)-4-(4-fL;Compound Fr13375;Paroxetine Impurity 18;Paroxetine impurities783;(3S,4R)-N-Methyl Paroxol;(3S,4R)-4-(4-Fluorophenyl)-3-h;[(3S,4R)-4-(4-Fluorophenyl)-1-methy;Paroxetine (3S,4R)-N-Methyl Paroxol Impurity
CBNumber
CB5737006
Molecular Formula
C13H18FNO
Formula Weight
223.29
MOL File
105812-81-5.mol
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(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Property

Melting point:
97-101 °C
alpha 
-38 º (c=1, MeOH)
Boiling point:
300.3±42.0 °C(Predicted)
Density 
1.092±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
14.93±0.10(Predicted)
color 
White to Almost white
InChI
InChI=1S/C13H18FNO/c1-15-7-6-13(11(8-15)9-16)10-2-4-12(14)5-3-10/h2-5,11,13,16H,6-9H2,1H3/t11-,13-/m0/s1
InChIKey
CXRHUYYZISIIMT-AAEUAGOBSA-N
SMILES
N1(C)CC[C@@H](C2=CC=C(F)C=C2)[C@H](CO)C1
CAS DataBase Reference
105812-81-5(CAS DataBase Reference)
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Safety

Hazard Codes 
N-Xn,N,Xn
Risk Statements 
51/53-41-22
Safety Statements 
61-39-26-22-37/39-24
RIDADR 
UN3077
HazardClass 
9
PackingGroup 
III
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0878
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$70
Updated
2024/03/01
TCI Chemical
Product number
F0878
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$259
Updated
2024/03/01
Alfa Aesar
Product number
H28137
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol, 98%
Packaging
5g
Price
$57.6
Updated
2021/12/16
Alfa Aesar
Product number
H28137
Product name
(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol, 98%
Packaging
25g
Price
$170
Updated
2021/12/16
TRC
Product number
P205800
Product name
Paroxol
Packaging
5g
Price
$110
Updated
2021/12/16
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(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

An intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor.

Uses

An intermediate in the synthesis of Paroxetine (P205750), a selective serotonin reuptake inhibitor.

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Suppliers

Hangzhou Benoy Chemical Co., Ltd.
Tel
17342059697
Fax
QQ:2710089141
Email
sales@benoychem.com
Country
China
ProdList
389
Advantage
58
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4767
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60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
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66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
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View Lastest Price from (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine 105812-81-5
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99.0%min
Supply Ability
200kg
Release date
2023-06-12
Shanghai CRM New Material Technology Co., LTD
Product
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine 105812-81-5
Price
US $10.00-15.00/g
Min. Order
10g
Purity
99%
Supply Ability
2546245
Release date
2022-09-20
Career Henan Chemical Co
Product
(-)-Trans-1-methyl-3-hydroxymethyl-4-(4-fluorophenyl)piperdine 105812-81-5
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100
Release date
2018-07-26

105812-81-5, (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidineRelated Search:


  • (-)-TRANS-4-(4-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (-)-TRANS-4R-(4-FLUOROPHENYL)-3S-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • TRANS-(-)-4-FLUOROPHENYL-1-METHYL-3-PIPERIDINE METHANOL
  • (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol,98%
  • (3S)-4-(4'-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (3S,4R)-4-(4'-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (3S,4R)-4-(4-FLUOROPHENYL)-3-HYDROXYMETHYL-1-METHYLPIPERIDINE
  • (4R,3S)4-(4-Fluorophenyl)-3-hydroxymethyl-1-methyl-piperidine
  • [(3S,4R)-4-(4-Fluorophenyl)-1- methylpiperidinyl]methanol,99%e.e.
  • Paroxetine Impurity 18
  • (3S,4R)-trans-(-)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
  • (-)Trans-1-N-Methyl-3-Hydroxy Methyl-4-(4-Fluoro Phenyl) Piperidine
  • Paroxetine (3S,4R)-N-Methyl Paroxol Impurity
  • [(3S,4R)-4-(4-fluorophenyl)-1-methyl-3-piperidyl]methanol
  • (4R,3S)-4-(4-FLUOROPHENYL)-3-HYDROXY METHYL-N-METHYL PIPERIDINE
  • (-)-Trans-4R-(4-Fluorophenyl)-3S-hydroxymethyl-N-methylpiperidine
  • (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol, 98%
  • Trans-(-)-4-(4-Fluorophenyl)-1-Methyl-3-Piperidine Methanol
  • PAROXOL
  • 4, (-)trans-4R-(4-fluorophenyl)-3S-hydroxymethyl-1-methylpiperidine
  • 3-Piperidinemethanol,4-(4-fluorophenyl)-1-methyl-,(3S,4R)-  
  • (4S,3S)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
  • (3S,4R)-4-(4-Fluorophenyl)-3-h
  • (2S)-1-(4-FLUOROPHENYL)-4-METHYLPIPERAZIN-2-YL]METHANOL
  • ((3S,4S)-4-(4-fluorophenyl)-1-Methylpiperidin-3-yl)Methanol
  • (3S-trans)-4-(4-Fluorophenyl)-1-Methyl-3-piperidineMethanol
  • (4R,3S)-4-(4-Fluorophenyl)-1-Methyl-3-piperidineMethanol
  • (3S,4R)-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine,98%
  • 3S,4R-4-[(4-fluorophenyl)-1-methylpiperi dinyl] methanol
  • (-)-Trans-1-methyl-3-hydroxymethyl-4-(4-fluorophenyl)piperdine
  • Paroxetine IMpurity - (3S,4R)-N-Methyl Paroxol
  • (3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol &gt
  • [(3S,4R)-4-(4-Fluorophenyl)-1-methy
  • [(3S,4S)-4-(4-fL
  • (-)Trans-4'-fluorophenyl-3-hydroxymethyl-l-methylpiperidine
  • (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidin...
  • Paroxetine impurities783
  • (3S,4R)-N-Methyl Paroxol
  • (-)TRANS-4R-(4-FLUOROPHENYL)-3S-HYDROXYMETHYL-1-METHYL PIPERIDINE
  • (3S,4R)-3-hydroxymethyl-4-(4'-fluorophenyl)-N-methylpiperidine
  • (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-met
  • Compound Fr13375
  • (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine OR (-) - Alcohol or (-) Carbinol
  • (-)-Paroxol
  • 105812-81-5
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • chiral
  • (intermediate of paroxetine)
  • bc0001