ChemicalBook > CAS DataBase List > 3,5,6-Trichloro-2-pyridinol

3,5,6-Trichloro-2-pyridinol

Product Name
3,5,6-Trichloro-2-pyridinol
CAS No.
6515-38-4
Chemical Name
3,5,6-Trichloro-2-pyridinol
Synonyms
TCP;6516-38-4;PYRIDINOL;3,5,6-TRICHLOROPYRIDINOL;3,5,6-TRICHLOROPYRIDIN-2-OL;2-HYDROXY-3,5,6-TRICHLOROPYRIDINE;PCTT;Spink3;3,5,6-Trichloro-;Ethiprole, Pestanal
CBNumber
CB5743506
Molecular Formula
C5H2Cl3NO
Formula Weight
198.43
MOL File
6515-38-4.mol
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3,5,6-Trichloro-2-pyridinol Property

Melting point:
328-330°C
Boiling point:
265℃
Density 
1.955
refractive index 
1.556
Flash point:
410℃
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.78±0.10(Predicted)
form 
Solid
color 
White to off-white
Water Solubility 
0.22g/L(temperature not stated)
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
6515-38-4(CAS DataBase Reference)
NIST Chemistry Reference
3,5,6-Trichloro-2-pyridinol(6515-38-4)
EPA Substance Registry System
3,5,6-Trichloro-2-pyridinol (6515-38-4)
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Safety

Hazard Codes 
Xn;N,N,Xn
Risk Statements 
22-41-51/53
Safety Statements 
26-39-61
RIDADR 
UN 3077
WGK Germany 
2
RTECS 
UU7786700
HazardClass 
9
PackingGroup 
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
33972
Product name
3,5,6-Trichloro-2-pyridinol
Purity
PESTANAL?, analytical standard
Packaging
100mg
Price
$67.4
Updated
2025/07/31
Sigma-Aldrich
Product number
33972
Product name
3,5,6-Trichloro-2-pyridinol
Purity
PESTANAL?, analytical standard
Packaging
100mg-r
Price
$50.1
Updated
2021/12/16
TCI Chemical
Product number
T3444
Product name
3,5,6-Trichloropyridine-2-ol
Packaging
1G
Price
$36
Updated
2025/07/31
TCI Chemical
Product number
T3444
Product name
3,5,6-Trichloropyridine-2-ol
Packaging
5G
Price
$108
Updated
2025/07/31
TRC
Product number
T773860
Product name
3,5,6-Trichloro-2-pyridinol
Packaging
100mg
Price
$95
Updated
2021/12/16
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3,5,6-Trichloro-2-pyridinol Chemical Properties,Usage,Production

Chemical Properties

powder

Uses

A metabolite of Chlorpyrifos (C425300).

Definition

ChEBI: A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos.

Hazard

Moderately toxic by ingestion and skin contact.

Synthesis

2402-79-1

6515-38-4

The general procedure for the synthesis of 3,5,6-trichloropyridin-2(1H)-one from 2,3,5,6-tetrachloropyridine: 2,3,5,6-tetrachloropyridine 43.4g (0.2 mol) and 240mL of deionized water were added into a three-necked flask, and the temperature was raised to 95℃ under stirring. Subsequently, 39.53 g (0.60 mol, 85% purity) of potassium hydroxide was slowly added and the pH of the reaction solution was adjusted to 9.5~10. Stirring was maintained at this temperature for 30 min, and the reaction was completed by filtration while hot to remove insoluble impurities. The filtrate was transferred to a 500 mL autoclave and 0.18 g of potassium hydroxide and benzyltrimethylammonium chloride were added as phase transfer catalyst. The autoclave was sealed, the reaction mixture was stirred and heated to 120 °C and kept at this temperature for 4.0 hours. At the end of the reaction, the reaction was cooled to 25 °C and the pH was adjusted to 4.0~4.5 with 15% hydrochloric acid solution. the reaction mixture was filtered and the resulting solid was washed with deionized water and dried to give 35.9 g of a white powdery product 3,5,6-trichloropyridin-2(1H)-one. The purity of the product was 99.08% by gas chromatography.

References

[1] Synthetic Communications, 2004, vol. 34, # 16, p. 2903 - 2909
[2] Patent: CN108395398, 2018, A. Location in patent: Paragraph 0008-0011

3,5,6-Trichloro-2-pyridinol Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5,6-Trichloro-2-pyridinol Suppliers

Shanghai Scochem Technology Co., Ltd.
Tel
021-33758897
Email
sales@scochem.com
Country
China
ProdList
1596
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
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Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
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China
ProdList
14101
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
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64
Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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42934
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64
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
ProdList
32321
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50
Beijing Isomersyn Technology CO;LTD
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010-82954736 13391601435
Email
sales@isomersyn.com
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China
ProdList
3295
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Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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HANSHANG CHEMICAL SCIENTIFIC LIMITED
Tel
021-50521775 15800962688
Fax
86-21-58306291
Email
sales@hanshangchem.com
Country
China
ProdList
471
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View Lastest Price from 3,5,6-Trichloro-2-pyridinol manufacturers

Career Henan Chemical Co
Product
3,5,6-Trichloro-2-pyridinol 6515-38-4
Price
US $1.00/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1000kg
Release date
2019-06-26

6515-38-4, 3,5,6-Trichloro-2-pyridinolRelated Search:


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  • 6516-38-4
  • Chlorpyrifos Impurity 3
  • 3,5,6-TRICHLORO-2-PYRIDINOL (TCPY) (4,5,6-13C3, 99%) CP 97% 100 UG/ML IN ACETONITRILE
  • 3,5,6-TRICHLORO-2-PYRIDINOL (TCPY) UNLABELED 100 UG/ML IN ACETONITRILE
  • 3,5,6-Trichloro-2-pyridinol ISO 9001:2015 REACH
  • 3,5,6-Trichloro-2-pyridinole 100 μg/ml Methanol
  • Clopyrithion impurity 1
  • PCTT
  • Spink3
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  • 6515-38-4
  • 6516-38-4
  • C5H2Cl3NO
  • Heterocycles
  • Metabolites & Impurities
  • Phosphorylating and Phosphitylating Agents