2-AMINO-5-IODOPYRIMIDINE
- Product Name
- 2-AMINO-5-IODOPYRIMIDINE
- CAS No.
- 1445-39-2
- Chemical Name
- 2-AMINO-5-IODOPYRIMIDINE
- Synonyms
- 5-iodopyrimidin-2-amine;5-Iodo-2-pyrimidinamine;2-PyriMidinaMine,5-iodo-;2-AMINO-5-IODOPYRIMIDINE;5-Iodo-pyriMidin-2-ylaMine;2-Amino-5-iodopyrimidine,97%;2-Amino-5-Iodopyrimidine 98%;2-AMINO-5-IODOPYRIMIDINE ISO 9001：2015 REACH;5-Iodopyrimidin-2-amine, 2-Amino-5-iodo-1,3-diazine
- CBNumber
- CB5746880
- Molecular Formula
- C4H4IN3
- Formula Weight
- 221
- MOL File
- 1445-39-2.mol
2-AMINO-5-IODOPYRIMIDINE Property
- Melting point:
- 219 °C
- Boiling point:
- 364.9±34.0 °C(Predicted)
- Density
- 2.204±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder
- pka
- 2.08±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
- Sensitive
- Light Sensitive
- InChI
- InChI=1S/C4H4IN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8)
- InChIKey
- HAFKCGZQRIIADX-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(I)C=N1
- CAS DataBase Reference
- 1445-39-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-41-37/38-22
- Safety Statements
- 37/39-26-39
- WGK Germany
- 3
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 691844
- Product name
- 2-Amino-5-iodopyrimidine
- Purity
- 97%
- Packaging
- 5g
- Price
- $243
- Updated
- 2023/06/20
- Product number
- A612675
- Product name
- 2-Amino-5-iodopyrimidine
- Packaging
- 10g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- A612675
- Product name
- 2-Amino-5-iodopyrimidine
- Packaging
- 5g
- Price
- $145
- Updated
- 2021/12/16
- Product number
- A612675
- Product name
- 2-Amino-5-iodopyrimidine
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA61596
- Product name
- 2-Amino-5-iodopyrimidine
- Packaging
- 2g
- Price
- $50
- Updated
- 2021/12/16
2-AMINO-5-IODOPYRIMIDINE Chemical Properties,Usage,Production
Chemical Properties
cream to brown crystalline powder
Uses
2-Amino-5-iodopyrimidine is used as a reactant in the synthesis of aminopyrimidine and cyclic guanidine amino acids.
Synthesis
109-12-6
1445-39-2
General procedure for the synthesis of 2-amino-5-iodopyrimidine from 2-aminopyrimidine: a mixture of 2-aminopyrimidine (2.4 g, 25 mmol, 1.0 eq.) and elemental iodine (2.7 g, 10.7 mmol, 0.43 eq.) was dissolved in 60 mL of glacial acetic acid, followed by the addition of periodate (0.86 g, 3.76 mmol, 0.15 eq.) and 0.5 mL of concentrated sulfuric acid dissolved in 3 mL of water. The reaction mixture was heated to 80 °C and maintained for 24 h under nitrogen protection. Upon completion of the reaction, the reaction mixture was poured into saturated aqueous sodium thiosulfate solution until the solution was clarified (200 mL each time for 3 times) and then extracted with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Purification by silica gel column chromatography afforded 2-amino-5-iodopyrimidine (1.4 g, 22.2% yield) as a white solid.
References
[1] Heterocycles, 1984, vol. 22, # 5, p. 1195 - 1210
[2] Journal of Organic Chemistry, 2000, vol. 65, # 22, p. 7468 - 7474
[3] Journal of Organic Chemistry, 2008, vol. 73, # 23, p. 9326 - 9333
[4] Synthesis, 1984, # 3, p. 252 - 254
[5] Patent: CN105622638, 2016, A. Location in patent: Paragraph 0362
2-AMINO-5-IODOPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-5-IODOPYRIMIDINE manufacturers
- Product
- 2-AMINO-5-IODOPYRIMIDINE 1445-39-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-07-05
- Product
- 2-AMINO-5-IODOPYRIMIDINE 1445-39-2
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-04
- Product
- 2-AMINO-5-IODOPYRIMIDINE 1445-39-2
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-03