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2-AMINO-5-IODOPYRIMIDINE

Product Name
2-AMINO-5-IODOPYRIMIDINE
CAS No.
1445-39-2
Chemical Name
2-AMINO-5-IODOPYRIMIDINE
Synonyms
5-iodopyrimidin-2-amine;5-Iodo-2-pyrimidinamine;2-PyriMidinaMine,5-iodo-;2-AMINO-5-IODOPYRIMIDINE;5-Iodo-pyriMidin-2-ylaMine;2-Amino-5-iodopyrimidine,97%;2-Amino-5-Iodopyrimidine 98%;2-AMINO-5-IODOPYRIMIDINE ISO 9001：2015 REACH;5-Iodopyrimidin-2-amine, 2-Amino-5-iodo-1,3-diazine
CBNumber
CB5746880
Molecular Formula
C4H4IN3
Formula Weight
221
MOL File
1445-39-2.mol
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2-AMINO-5-IODOPYRIMIDINE Property

Melting point:
219 °C
Boiling point:
364.9±34.0 °C(Predicted)
Density 
2.204±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder
pka
2.08±0.10(Predicted)
Appearance
Off-white to light yellow Solid
Sensitive 
Light Sensitive
InChI
InChI=1S/C4H4IN3/c5-3-1-7-4(6)8-2-3/h1-2H,(H2,6,7,8)
InChIKey
HAFKCGZQRIIADX-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(I)C=N1
CAS DataBase Reference
1445-39-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
37/39-26-39
WGK Germany 
3
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
691844
Product name
2-Amino-5-iodopyrimidine
Purity
97%
Packaging
5g
Price
$243
Updated
2023/06/20
TRC
Product number
A612675
Product name
2-Amino-5-iodopyrimidine
Packaging
10g
Price
$240
Updated
2021/12/16
TRC
Product number
A612675
Product name
2-Amino-5-iodopyrimidine
Packaging
5g
Price
$145
Updated
2021/12/16
TRC
Product number
A612675
Product name
2-Amino-5-iodopyrimidine
Packaging
1g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA61596
Product name
2-Amino-5-iodopyrimidine
Packaging
2g
Price
$50
Updated
2021/12/16
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2-AMINO-5-IODOPYRIMIDINE Chemical Properties,Usage,Production

Chemical Properties

cream to brown crystalline powder

Uses

2-Amino-5-iodopyrimidine is used as a reactant in the synthesis of aminopyrimidine and cyclic guanidine amino acids.

Synthesis

109-12-6

1445-39-2

General procedure for the synthesis of 2-amino-5-iodopyrimidine from 2-aminopyrimidine: a mixture of 2-aminopyrimidine (2.4 g, 25 mmol, 1.0 eq.) and elemental iodine (2.7 g, 10.7 mmol, 0.43 eq.) was dissolved in 60 mL of glacial acetic acid, followed by the addition of periodate (0.86 g, 3.76 mmol, 0.15 eq.) and 0.5 mL of concentrated sulfuric acid dissolved in 3 mL of water. The reaction mixture was heated to 80 °C and maintained for 24 h under nitrogen protection. Upon completion of the reaction, the reaction mixture was poured into saturated aqueous sodium thiosulfate solution until the solution was clarified (200 mL each time for 3 times) and then extracted with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Purification by silica gel column chromatography afforded 2-amino-5-iodopyrimidine (1.4 g, 22.2% yield) as a white solid.

References

[1] Heterocycles, 1984, vol. 22, # 5, p. 1195 - 1210
[2] Journal of Organic Chemistry, 2000, vol. 65, # 22, p. 7468 - 7474
[3] Journal of Organic Chemistry, 2008, vol. 73, # 23, p. 9326 - 9333
[4] Synthesis, 1984, # 3, p. 252 - 254
[5] Patent: CN105622638, 2016, A. Location in patent: Paragraph 0362

2-AMINO-5-IODOPYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-IODOPYRIMIDINE Suppliers

Canada 1 China 120 Germany 5 India 5 Japan 1 Switzerland 2 The Netherlands 1 United Kingdom 11 United States 30 Global 176
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
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View Lastest Price from 2-AMINO-5-IODOPYRIMIDINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-AMINO-5-IODOPYRIMIDINE 1445-39-2
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-07-05
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-AMINO-5-IODOPYRIMIDINE 1445-39-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-04
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
2-AMINO-5-IODOPYRIMIDINE 1445-39-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-03

1445-39-2, 2-AMINO-5-IODOPYRIMIDINERelated Search:

5-IODOPYRIMIDINE 4-Amino-5-iodopyrimidine 5-AMINO-2-IODOPYRIMIDINE 4-Iodopyrimidin-2-amine 4-AMINO-6-IODOPYRIMIDINE 2-AMINO-4-HYDROXY-5-IODO-6-PHENYLPYRIMIDINE 2-AMINO-4-HYDROXY-5-IODO-6-PHENOXYPYRIMIDINE 5-Iodo-2-(piperazin-1-yl)pyrimidine 2-AMINO-4,6-DIMETHYL-5-IODOPYRIMIDINE 2-AMINO-5-IODOPYRIMIDINE

  • 2-AMINO-5-IODOPYRIMIDINE
  • 5-Iodo-2-pyrimidinamine
  • 2-Amino-5-iodopyrimidine,97%
  • 5-Iodo-pyriMidin-2-ylaMine
  • 5-iodopyrimidin-2-amine
  • 5-Iodopyrimidin-2-amine, 2-Amino-5-iodo-1,3-diazine
  • 2-PyriMidinaMine,5-iodo-
  • 2-AMINO-5-IODOPYRIMIDINE ISO 9001：2015 REACH
  • 2-Amino-5-Iodopyrimidine 98%
  • 1445-39-2
  • 1445-29-2
  • C4H4IN3
  • AMINO
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines
  • Heterocycle-Pyrimidine series
  • Building Blocks
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Pyrimidine series
  • Pyrimidine
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyrimidines