2,2'-BIPYRIDINE-5-CARBOXYLIC ACID

Product Name: 2,2'-BIPYRIDINE-5-CARBOXYLIC ACID
CAS No.: 1970-80-5
Chemical Name: 2,2'-BIPYRIDINE-5-CARBOXYLIC ACID
Synonyms: DK7312;5-Carboxy-2,2'-bipyridine;5-Carboxy-2,2’-bipyridine;6-(2-pyridyl)nicotinic acid;2,2Bipyridyl-5-carboxylic acid;6-(Pyridin-2-yl)nicotinic acid;,2'-BIPYRIDINE-5-CARBOXYLIC ACID;2,2'-BIPYRIDINE-5-CARBOXYLIC ACID;BIPY443, 5-Carboxy-2,2'-bipyridine;2,2'-Bipyridine-5-carboxylic acid 95%
CBNumber: CB5755301
Molecular Formula: C11H8N2O2
Formula Weight: 200.19
MOL File: 1970-80-5.mol

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2,2'-BIPYRIDINE-5-CARBOXYLIC ACID Property

Melting point:: 218-220 °C
Boiling point:: 405.5±35.0 °C(Predicted)
Density: 1.302±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder
pka: 2.44±0.10(Predicted)
color: White
InChI: InChI=1S/C11H8N2O2/c14-11(15)8-4-5-10(13-7-8)9-3-1-2-6-12-9/h1-7H,(H,14,15)
InChIKey: LWMHPOLRJIRLPN-UHFFFAOYSA-N
SMILES: C1(C2=NC=CC=C2)=NC=C(C(O)=O)C=C1

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B593618
Product name: 2,2''-Bipyridine-5-carboxylicAcid
Packaging: 10mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-W004554
Product name: 6-(Pyridin-2-yl)pyridine-3-carboxylicacid
Purity: 99.55%
Packaging: 250mg
Price: $101
Updated: 2021/12/16

ChemScene

Product number: CS-W004554
Product name: 6-(Pyridin-2-yl)pyridine-3-carboxylicacid
Purity: 99.55%
Packaging: 1g
Price: $274
Updated: 2021/12/16

Apolloscientific

Product number: OR18622
Product name: 2,2'-Bipyridine-5-carboxylicacid
Purity: 95%
Packaging: 100mg
Price: $290
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H21-1-0D
Product name: 2,2'-Bipyridine-5-carboxylic acid
Packaging: 100mg
Price: $320
Updated: 2021/12/16

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2,2'-BIPYRIDINE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production

Application

2,2'-BIPYRIDINE-5-CARBOXYLIC ACID is a useful research chemical.

Synthesis

58792-53-3

1970-80-5

General procedure for the synthesis of [2,2'-bipyridine]-5-carboxylic acid from methyl [2,2'-bipyridine]-5-carboxylate: first, 2-chloro-5-methoxycarbonylpyridine (1.3 g, 7.6 mmol) was dissolved in 20 ml of mesitylene, PdCl2(PPh3)2 (0.27 g, 0.04 mmol) and 2-trimethylpyridine (2.1 g, 8.6 mmol). The mixture was heated to reflux for 20 hours. After completion of the reaction, it was left to cool, diluted with ether and filtered through a neutral alumina column. The filtrate was washed several times with water and dried with anhydrous sodium sulfate. After evaporation of the solvent, it was purified by silica gel column chromatography to give 1.13 g of compound 10 as a white solid in 70% yield. Subsequently, compound 10 (1.13 g, 5.3 mmol) was suspended in 120 ml of ethanol/water mixed solvent in the ratio of 1:120 and a solution prepared by dissolving KOH (0.35 g, 6.3 mmol) in 2 ml of water was added and the reaction was stirred for 3 hours. After completion of the reaction, the ethanol was removed by distillation and concentration and adjusted to neutral by adding 1 mol/L hydrochloric acid. The resulting suspension was extracted three times with chloroform, the extract was washed with water, dried with anhydrous sodium sulfate and distilled to remove the solvent. The crude product was purified by silica gel column chromatography to afford 0.8 g of compound 11 as a light yellow solid in 75% yield.

References

[1] Organic Letters, 2007, vol. 9, # 26, p. 5333 - 5336
[2] Angewandte Chemie - International Edition, 2012, vol. 51, # 32, p. 8097 - 8100
[3] Tetrahedron, 2013, vol. 69, # 14, p. 3019 - 3026
[4] Journal of Organic Chemistry, 1999, vol. 64, # 3, p. 1015 - 1021
[5] Patent: JP6081152, 2017, B2. Location in patent: Paragraph 0015; 0037; 0038

2,2'-BIPYRIDINE-5-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2'-BIPYRIDINE-5-CARBOXYLIC ACID Suppliers

China 93 Germany 1 India 1 United Kingdom 2 United States 9 Global 106

Shanghai UCHEM Inc.

Tel: 18939844854
Fax: QQ3004479448
Email: sales6@myuchem.com
Country: China
ProdList: 4997
Advantage: 58

Beijing HwrkChemical Technology Co., Ltd

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Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
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Energy Chemical

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Shanghai Jian Chao Chemical Technology Co., Ltd.

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Bide Pharmatech Ltd.

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Zhengzhou ALFA Chemical Co., Ltd.

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SunaTech Inc.

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Suzhou Laing Biological Technology Co., LTD

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Shanghai Xingui Biotechnology Co., Ltd.

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Cool Pharm, Ltd

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View Lastest Price from 2,2'-BIPYRIDINE-5-CARBOXYLIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: ,2'-BIPYRIDINE-5-CARBOXYLIC ACID 1970-80-5
Price: US $3.00-9.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 50kg
Release date: 2025-07-28

Shanghai UCHEM Inc.

Product: 2,2'-Bipyridine-5-carboxylic acid 1970-80-5
Price: US $50.00-449.00/g
Min. Order: 1g
Purity: 0.98
Supply Ability: 10kg
Release date: 2024-10-25

Dideu Industries Group Limited

Product: 2,2'-BIPYRIDINE-5-CARBOXYLIC ACID 1970-80-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-27

1970-80-5, 2,2'-BIPYRIDINE-5-CARBOXYLIC ACIDRelated Search:

2,2-bipyridine-6-carboxylic acid 4-Bromo-2,2''-bipyridine 5-BROMO-2,2'-BIPYRIDINE 4'-CHLORO-2,2':6',2''-TERPYRIDINE 2,2'-DIPYRIDYL N,N'-DIOXIDE 2,2':6',2''-TERPYRIDINE-4,4',4''-TRICARBOXYLIC ACID 4,4'-Dimethyl-2,2'-bipyridyl 4‘-(4-hydroxyphenyl)-2, 2':6‘, 2“-terpyridine 1,3,5-Tris(m-iodophenyl)benzene 4'-BROMO-2,2':6',2''-TERPYRIDINE 4-Methyl-4'-(3-carboxypropyl)-2,2'-bipyridine 6-BROMO-2,2'-BIPYRIDINE [2,2':6',2''-TERPYRIDINE]-3',4'-DICARBOXYLIC ACID 2,2'-Bipyridine-5,5'-dicarboxylic acid 2,2'-BIPYRIDINE-5-CARBALDEHYDE 2,2'-BIPYRIDINE-5-CARBOXYLIC ACID ETHYL 6-BROMO-2,2'-BIPYRIDINE-5'-CARBOXYLATE

2,2'-BIPYRIDINE-5-CARBOXYLIC ACID

6-(2-pyridyl)nicotinic acid

6-pyridin-2-ylpyridine-3-carboxylic acid

6-(Pyridin-2-yl)nicotinic acid

2,2Bipyridyl-5-carboxylic acid

5-Carboxy-2,2'-bipyridine

BIPY443, 5-Carboxy-2,2'-bipyridine

2,2'-Bipyridine-5-carboxylic acid 95%

2,2'-BIPYRIDINE-5-CARBOXYLIC ACID ISO 9001：2015 REACH

6-pyridin-2-ylpyridine-3-carboxylicaci

DK7312

5-Carboxy-2,2’-bipyridine

2,2′-Bipyridine-5-carboxylic acid, CAS 1970-80-5

,2'-BIPYRIDINE-5-CARBOXYLIC ACID

1970-80-5

Carboxylic Acids

Pyridines

Carboxylic Acids