3,4-DIHYDROQUINOLIN-2(1H)-ONE
- Product Name
- 3,4-DIHYDROQUINOLIN-2(1H)-ONE
- CAS No.
- 553-03-7
- Chemical Name
- 3,4-DIHYDROQUINOLIN-2(1H)-ONE
- Synonyms
- 3,4-DIHYDRO-1H-QUINOLIN-2-ONE;HYDROCARBOSTYRIL;3,4-DIHYDRO-2(1H)-QUINOLINONE;inone;DIHYDROCARBOSTYRIL;dihydro-α-quinolone;3,4-Dihydrocarbostyril;3,4-Dihydro-2-quinolone;3,4-Dihydro-2(1H)-quinoL;3,4-Dihydro-2-quinolinone
- CBNumber
- CB5772351
- Molecular Formula
- C9H9NO
- Formula Weight
- 147.17
- MOL File
- 553-03-7.mol
3,4-DIHYDROQUINOLIN-2(1H)-ONE Property
- Melting point:
- 165-167 °C (lit.)
- Boiling point:
- 267.28°C (rough estimate)
- Density
- 1.1135 (rough estimate)
- refractive index
- 1.5200 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
- form
- Crystalline Powder
- pka
- 14.76±0.20(Predicted)
- color
- Off-white
- Water Solubility
- Slightly soluble in water.
- Sensitive
- Light Sensitive
- Merck
- 13,4800
- CAS DataBase Reference
- 553-03-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-43
- Safety Statements
- 26-36/37
- RIDADR
- 2811
- WGK Germany
- 2
- Hazard Note
- Irritant
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29337900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 415936
- Product name
- 3,4-Dihydro-2(1H)-quinolinone
- Purity
- 98%
- Packaging
- 10g
- Price
- $171
- Updated
- 2023/06/20
- Product number
- 415936
- Product name
- 3,4-Dihydro-2(1H)-quinolinone
- Purity
- 98%
- Packaging
- 1g
- Price
- $39.4
- Updated
- 2023/01/07
- Product number
- H36638
- Product name
- 3,4-Dihydro-2-(1H)-quinolinone, 98%
- Packaging
- 1g
- Price
- $42.65
- Updated
- 2024/03/01
- Product number
- H36638
- Product name
- 3,4-Dihydro-2-(1H)-quinolinone, 98%
- Packaging
- 5g
- Price
- $128.65
- Updated
- 2024/03/01
- Product number
- H36638
- Product name
- 3,4-Dihydro-2-(1H)-quinolinone
- Purity
- 98%
- Packaging
- 25g
- Price
- $440
- Updated
- 2021/12/16
3,4-DIHYDROQUINOLIN-2(1H)-ONE Chemical Properties,Usage,Production
Chemical Properties
Off-white crystalline powder
Uses
3,4-Dihydro-2-(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments. It is used to prepare potent bicyclic peptide deformylase inhibitors with antibacterial effects. It is also used to synthesize substituted iminopiperidines as inhibitors of human nitric oxide synthase isoforms.
Uses
3,4-Dihydro-2(1H)-quinolinone may be employed as medium supplement in the culture medium of Pseudomonas ayucida during enrichment culture experiments.
Definition
ChEBI: 3,4-Dihydro-2(1H)-quinolinone is a member of quinolines.
Synthesis Reference(s)
Journal of the American Chemical Society, 89, p. 7131, 1967 DOI: 10.1021/ja01002a061
Tetrahedron Letters, 36, p. 125, 1995 DOI: 10.1016/0040-4039(94)02191-D
General Description
Series of 3,4-dihydro-2(1H)-quinolinone derivatives having sigma-1 receptor (σ1R) antagonist activity have been synthesized. 3,4-dihydro-2((1)H)-quinolinones have been synthesized using N-(1′-alkoxy)cyclopropyl-2-haloanilines as starting reagent. Cyclopropane ring expansion in the presence of palladium catalyst is the major step involved in the synthesis. Library of 3,4-dihydro-2(1H)-quinolinones have been synthesized through the rearrangement of β-lactam intermediates on the solid-phase
3,4-DIHYDROQUINOLIN-2(1H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,4-DIHYDROQUINOLIN-2(1H)-ONE manufacturers
- Product
- 1,2,3,4-Tetrahydroquinolin-2-one 553-03-7
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-14
- Product
- 1,2,3,4-Tetrahydroquinolin-2-one 553-03-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kgs
- Release date
- 2020-02-13