ChemicalBook > CAS DataBase List > PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT

PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT

Product Name
PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT
CAS No.
4265-07-0
Chemical Name
PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT
Synonyms
PEP;PEP-K;PEP, potassium salt;PEP MONOPOTASSIUM SALT;POTASSIUM PHOSPHOENOLPYRUVATE;PEP-K, metabolic intermediate;MONOPOTASSIUM PHOSPHOENOLPYRUVATE;PHOSPHOENOLPYRUVATE POTASSIUM SALT;PHOSPHO(ENOL)PYRUVATE MONOPOTASSIUM;1-carboxyethenyl hydrogen phosphate
CBNumber
CB5778797
Molecular Formula
C3H4KO6P
Formula Weight
206.13
MOL File
4265-07-0.mol
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PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Property

Melting point:
175 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
solid
color 
White to off-white
Water Solubility 
Soluble in water. Slightly soluble in methanol.
Sensitive 
Hygroscopic
BRN 
4603446
CAS DataBase Reference
4265-07-0(CAS DataBase Reference)
EPA Substance Registry System
2-Propenoic acid, 2-(phosphonooxy)-, monopotassium salt (4265-07-0)
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Safety

Safety Statements 
24/25
WGK Germany 
3
F 
3-10
TSCA 
Yes
HS Code 
29199000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
860077
Product name
Phospho(enol)pyruvic acid monopotassium salt
Purity
99%
Packaging
250mg
Price
$177
Updated
2024/03/01
Sigma-Aldrich
Product number
860077
Product name
Phospho(enol)pyruvic acid monopotassium salt
Purity
99%
Packaging
1g
Price
$242
Updated
2024/03/01
Sigma-Aldrich
Product number
10108294001
Product name
Phosphoenol-pyruvate
Purity
PEP,monopotassiumsalt
Packaging
1g
Price
$366
Updated
2024/03/01
Alfa Aesar
Product number
B20358
Product name
Phosphoenolpyruvic acid monopotassium salt, 99%
Packaging
5g
Price
$206
Updated
2024/03/01
Alfa Aesar
Product number
B20358
Product name
Phosphoenolpyruvic acid monopotassium salt, 99%
Packaging
25g
Price
$819
Updated
2024/03/01
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PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Chemical Properties,Usage,Production

Description

Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase. One molecule of ATP is formed during its metabolism in this pathway. During gluconeogenesis, it is formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation and GTP hydrolysis. In plants, it is metabolized to form aromatic amino acids and also serves as a substrate for phosphoenolpyruvate carboxylase-catalyzed carbon fixation.

Chemical Properties

white to light yellow fine crystalline powder

Uses

Substrate for many kinase reactions.

Uses

Phosphoenolpyruvic acid monopotassium salt is used in glycolysis and gluconeogeneis. It is used for regeneration of ATP from ADP in enzyme-catalyzed syntheses. It is metabolized by an enzyme namely pyruvate kinase to yield pyruvate. It acts as protection against cell injury induced by oxidative stress and against dysfunction in carbohydrate metabolism.

General Description

Phospho(enol)pyruvic acid (PEP) acts as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase. It is a bifunctional carbohydrate, which exhibits antioxidant property. PEP may be a potential organ preservation agent in clinical transplantation.

Biochem/physiol Actions

Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Purification Methods

KPEP is purified via the monocyclohexylamine salt (see next entry). The salt (534mg) in H2O (10mL) is added to Dowex 50Wx4 H+ form (200-400 mesh, 2mL, H2O washed) and stirred gently for 30minutes and filtered. The resin is washed with H2O (6mL), and the combined solutions are adjusted to pH 7.4 with 3N KOH (~1.4mL) and the volume adjusted to 18.4mL with H2O to give a solution of 0.1M KPEP which can be lyophilised to a pure powder and is very good for enzyme work. It has been recrystallised from MeOH/Et2O. [Clark & Kirby Biochemical Preparations 11 103 1966, Wold & Ballou J Biol Chem 227 301 1957, Cherbuliez & Rabinowitz Helv Chim Acta 39 1461 1956, Beilstein 3 IV 977.] The triNa salt [5541-93-5] M 360.0, is purified as follows: the salt (1g) is dissolved in MeOH (40mL) and dry Et2O is added in excess. The white crystals are collected and dried over P2O5 at 20o. [Cramer & Voges Chem Ber 92 952 1959, Beilstein 3 IV 977.]

PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Suppliers

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View Lastest Price from PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Phosphoenolpyruvic acid Monopotassium salt 4265-07-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-03
Shaanxi Dideu Medichem Co. Ltd
Product
Phospho(enol)pyruvic acid monopotassium salt 4265-07-0
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2020-01-14
R&D Scientific Inc.
Product
Potassium 1-carboxyvinyl hydrogenphosphate 4265-07-0
Price
US $1980.00/Kg
Min. Order
1Kg
Purity
95 %
Supply Ability
500 Kg
Release date
2024-03-02

4265-07-0, PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALTRelated Search:

Pyridoxal phosphate EC 2.7.1.40 EC 6.4.1.1 Phenyl chlorothionocarbonate Amifostine Thiol Dihydrochloride Potassium di-tert-butyl phosphate Phosphoenolpyruvic acid cyclohexylammonium salt PHOSPHOENOLPYRUVIC ACID TRIS(CYCLOHEXYLAMMONIUM) SALT Pyruvic acid Monopotassium phosphite Potassium hypophosphite Potassium Phosphate Monobasic PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT EPC-K(1) vinyl phosphate

  • 2H-1-Benzopyran-2-carboxylic acid, 6-chloro-3,4-dihydro-, (2S)
  • 2-(Phosphonooxy)-2-propenoic acid monopotassium sal
  • Phosphoenolpyruvic Acid Monopotassium Salt 〔PEP, Monopotassium Salt〕
  • 2-(phosphonooxy)-2-propenoicacimonopotassiumsalt
  • Potassium 1-carboxyvinyl hydrogenphosphate
  • Phospho(enol)pyruvic acid MonopotassiuM salt 99%
  • PEP-K
  • PEP MONOPOTASSIUM SALT
  • PEP
  • POTASSIUM PHOSPHOENOLPYRUVATE
  • PHOSPHO(ENOL)PYRUVIC ACID POTASSIUM SALT
  • PHOSPHOENOLPYRUVATE POTASSIUM SALT
  • PHOSPHO(ENOL)PYRUVATE MONOPOTASSIUM SALT
  • PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT
  • 2-[PHOSPHONOOXY]-2-PROPENOIC ACID MONOPOTASSIUM SALT
  • Phosphoenolpyruvic Acid, Monopotassium Salt (unlabelled)
  • Potassium Phosphoenol Pyruvate-2,3-13C2
  • Potassium Phosphoenol Pyruvate-2-13C
  • Potassium Phosphoenol Pyruvate-3-13C
  • potassium hydrogen 2-(phosphonatooxy)acrylate
  • PHOSPHO(ENOL)PYRUVATE MONOPOTASSIUM
  • PEP, potassium salt
  • mono-Potassium phosphoenolpyruvate, PEP monopotassium salt, PEP-K, Phospho(enol)pyruvate potassium salt
  • 2-(Phosphonooxy)-2-propenoic acid monopotassium salt, mono-Potassium phosphoenolpyruvate, PEP-K
  • MONOPOTASSIUM PHOSPHOENOLPYRUVATE
  • Phosphoenolpyruvic acid monopotassium salt,99%
  • PotassiuM phosphoenolpyruvate, PEP-K, 2-Phosphonooxy-acrylic acid · potassiuM salt
  • 2-Propenoic acid,2-(phosphonooxy)-, potassium salt (1:1)
  • Phospho(enol)pyruvic acid monopotassium
  • 1-carboxyethenyl hydrogen phosphate
  • PEP-K, metabolic intermediate
  • 4265-07-0
  • 4565-07-0
  • KOPOOHOCCH2COOH
  • CH2CCOOHOPOHO2K
  • KOPOOHOCCH2CO2H
  • C3H4KO6P
  • C3H4O6PK
  • Carbohydrate Library
  • BioChemical
  • Biochemicals and Reagents
  • Building Blocks
  • Pyruvate kinase
  • Phosphorus Compounds
  • Organic Phosphates/Phosphites
  • Substrates by Enzyme
  • Metabolic Libraries
  • Metabolomics
  • Organic Building Blocks
  • Enzyme Substrates
  • Enzymes, Inhibitors, and Substrates
  • Building Blocks
  • Chemical Synthesis
  • Organic Building Blocks
  • Organic Phosphates/Phosphites
  • Phosphorus Compounds
  • metabolite