PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT

Product Name: PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT
CAS No.: 4265-07-0
Chemical Name: PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT
Synonyms: PEP;PEP-K;PEP, potassium salt;PEP MONOPOTASSIUM SALT;POTASSIUM PHOSPHOENOLPYRUVATE;MONOPOTASSIUM PHOSPHOENOLPYRUVATE;PHOSPHOENOLPYRUVATE POTASSIUM SALT;PHOSPHO(ENOL)PYRUVATE MONOPOTASSIUM;1-carboxyethenyl hydrogen phosphate;Potassium Phosphoenol Pyruvate-2-13C
CBNumber: CB5778797
Molecular Formula: C3H4KO6P
Formula Weight: 206.13
MOL File: 4265-07-0.mol

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PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Property

Melting point:: 175 °C (dec.)(lit.)
storage temp.: 2-8°C
solubility: Methanol (Slightly), Water (Slightly)
form: solid
color: White to off-white
Water Solubility: Soluble in water. Slightly soluble in methanol.
Sensitive: Hygroscopic
BRN: 4603446
CAS DataBase Reference: 4265-07-0(CAS DataBase Reference)
EPA Substance Registry System: 2-Propenoic acid, 2-(phosphonooxy)-, monopotassium salt (4265-07-0)

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Safety

Safety Statements: 24/25
WGK Germany: 3
F: 3-10
TSCA: Yes
HS Code: 29199000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 860077
Product name: Phospho(enol)pyruvic acid monopotassium salt
Purity: 99%
Packaging: 250mg
Price: $177
Updated: 2024/03/01

Sigma-Aldrich

Product number: 860077
Product name: Phospho(enol)pyruvic acid monopotassium salt
Purity: 99%
Packaging: 1g
Price: $242
Updated: 2024/03/01

Sigma-Aldrich

Product number: 10108294001
Product name: Phosphoenol-pyruvate
Purity: PEP,monopotassiumsalt
Packaging: 1g
Price: $366
Updated: 2024/03/01

Alfa Aesar

Product number: B20358
Product name: Phosphoenolpyruvic acid monopotassium salt, 99%
Packaging: 5g
Price: $206
Updated: 2024/03/01

Alfa Aesar

Product number: B20358
Product name: Phosphoenolpyruvic acid monopotassium salt, 99%
Packaging: 25g
Price: $819
Updated: 2024/03/01

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PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Chemical Properties,Usage,Production

Description

Phosphoenolpyruvic acid plays a role in both glycolysis and gluconeogenesis. During glycolysis, it is formed by the action of enolase on 2-phosphoglycerate and is metabolized to pyruvate by pyruvate kinase. One molecule of ATP is formed during its metabolism in this pathway. During gluconeogenesis, it is formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation and GTP hydrolysis. In plants, it is metabolized to form aromatic amino acids and also serves as a substrate for phosphoenolpyruvate carboxylase-catalyzed carbon fixation.

Chemical Properties

white to light yellow fine crystalline powder

Uses

Substrate for many kinase reactions.

Uses

Phosphoenolpyruvic acid monopotassium salt is used in glycolysis and gluconeogeneis. It is used for regeneration of ATP from ADP in enzyme-catalyzed syntheses. It is metabolized by an enzyme namely pyruvate kinase to yield pyruvate. It acts as protection against cell injury induced by oxidative stress and against dysfunction in carbohydrate metabolism.

General Description

Phospho(enol)pyruvic acid (PEP) acts as an inhibitor of hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase. It is a bifunctional carbohydrate, which exhibits antioxidant property. PEP may be a potential organ preservation agent in clinical transplantation.

Biochem/physiol Actions

Phospho(enol)pyruvic acid (PEP) is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Purification Methods

KPEP is purified via the monocyclohexylamine salt (see next entry). The salt (534mg) in H2O (10mL) is added to Dowex 50Wx4 H+ form (200-400 mesh, 2mL, H2O washed) and stirred gently for 30minutes and filtered. The resin is washed with H2O (6mL), and the combined solutions are adjusted to pH 7.4 with 3N KOH (~1.4mL) and the volume adjusted to 18.4mL with H2O to give a solution of 0.1M KPEP which can be lyophilised to a pure powder and is very good for enzyme work. It has been recrystallised from MeOH/Et2O. [Clark & Kirby Biochemical Preparations 11 103 1966, Wold & Ballou J Biol Chem 227 301 1957, Cherbuliez & Rabinowitz Helv Chim Acta 39 1461 1956, Beilstein 3 IV 977.] The triNa salt [5541-93-5] M 360.0, is purified as follows: the salt (1g) is dissolved in MeOH (40mL) and dry Et2O is added in excess. The white crystals are collected and dried over P2O5 at 20o. [Cramer & Voges Chem Ber 92 952 1959, Beilstein 3 IV 977.]

PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT Suppliers

Canada 3 China 136 France 1 Germany 4 India 5 Japan 4 Switzerland 2 United Kingdom 6 United States 31 Global 192

Watec Laboratories, Inc.

Tel: 18602586511
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Zhengzhou Kangshan Biological Co., Ltd.

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Chengdu Zhongde Jihua Pharmaceutical Technology Co., Ltd

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Zhengzhou Kingsfine Chemical Co., Ltd.

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Shanghai Boyle Chemical Co., Ltd.

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J & K SCIENTIFIC LTD.

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Alfa Aesar

Tel: 400-6106006
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Energy Chemical

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky (shanghai) International Co.,Ltd

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View Lastest Price from PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Phosphoenolpyruvic acid Monopotassium salt 4265-07-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-03

Shaanxi Dideu Medichem Co. Ltd

Product: Phospho(enol)pyruvic acid monopotassium salt 4265-07-0
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-01-14

R&D Scientific Inc.

Product: Potassium 1-carboxyvinyl hydrogenphosphate 4265-07-0
Price: US $1980.00/Kg
Min. Order: 1Kg
Purity: 95 %
Supply Ability: 500 Kg
Release date: 2024-03-02

4265-07-0, PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALTRelated Search:

Pyridoxal phosphate EC 2.7.1.40 EC 6.4.1.1 Phenyl chlorothionocarbonate Amifostine Thiol Dihydrochloride Potassium di-tert-butyl phosphate Phosphoenolpyruvic acid cyclohexylammonium salt PHOSPHOENOLPYRUVIC ACID TRIS(CYCLOHEXYLAMMONIUM) SALT Pyruvic acid Monopotassium phosphite Potassium hypophosphite Potassium Phosphate Monobasic PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT EPC-K(1) vinyl phosphate

2H-1-Benzopyran-2-carboxylic acid, 6-chloro-3,4-dihydro-, (2S)

2-(Phosphonooxy)-2-propenoic acid monopotassium sal

Phosphoenolpyruvic Acid Monopotassium Salt 〔PEP, Monopotassium Salt〕

2-(phosphonooxy)-2-propenoicacimonopotassiumsalt

Potassium 1-carboxyvinyl hydrogenphosphate

Phospho(enol)pyruvic acid MonopotassiuM salt 99%

PEP-K

PEP MONOPOTASSIUM SALT

PEP

POTASSIUM PHOSPHOENOLPYRUVATE

PHOSPHO(ENOL)PYRUVIC ACID POTASSIUM SALT

PHOSPHOENOLPYRUVATE POTASSIUM SALT

PHOSPHO(ENOL)PYRUVATE MONOPOTASSIUM SALT

PHOSPHOENOLPYRUVIC ACID MONOPOTASSIUM SALT

2-[PHOSPHONOOXY]-2-PROPENOIC ACID MONOPOTASSIUM SALT

Phosphoenolpyruvic Acid, Monopotassium Salt (unlabelled)

Potassium Phosphoenol Pyruvate-2,3-13C2

Potassium Phosphoenol Pyruvate-2-13C

Potassium Phosphoenol Pyruvate-3-13C

potassium hydrogen 2-(phosphonatooxy)acrylate

PHOSPHO(ENOL)PYRUVATE MONOPOTASSIUM

PEP, potassium salt

mono-Potassium phosphoenolpyruvate, PEP monopotassium salt, PEP-K, Phospho(enol)pyruvate potassium salt

2-(Phosphonooxy)-2-propenoic acid monopotassium salt, mono-Potassium phosphoenolpyruvate, PEP-K

MONOPOTASSIUM PHOSPHOENOLPYRUVATE

Phosphoenolpyruvic acid monopotassium salt,99%

PotassiuM phosphoenolpyruvate, PEP-K, 2-Phosphonooxy-acrylic acid · potassiuM salt

2-Propenoic acid,2-(phosphonooxy)-, potassium salt (1:1)

Phospho(enol)pyruvic acid monopotassium

1-carboxyethenyl hydrogen phosphate

4265-07-0

4565-07-0

KOPOOHOCCH2COOH

CH2CCOOHOPOHO2K

KOPOOHOCCH2CO2H

C3H4KO6P

C3H4O6PK

Carbohydrate Library

BioChemical

Biochemicals and Reagents

Building Blocks

Pyruvate kinase

Phosphorus Compounds

Organic Phosphates/Phosphites

Substrates by Enzyme

Metabolic Libraries

Metabolomics

Organic Building Blocks

Enzyme Substrates

Enzymes, Inhibitors, and Substrates

Building Blocks

Chemical Synthesis

Organic Building Blocks

Organic Phosphates/Phosphites

Phosphorus Compounds

metabolite