2-Amino-1-pyrroline Hydrochloride

Uses

Product Name: 2-Amino-1-pyrroline Hydrochloride
CAS No.: 7544-75-4
Chemical Name: 2-Amino-1-pyrroline Hydrochloride
Synonyms: Tipiracil-004-HCl;2-Aminopyrrolidine;Tipiracil Impurity 13;2-AMinopyrrolidine HCl;2-Amino-1-pyrroline HCl;Tipiracil Impurity 1 HCl;Tipiracil Impurity 6 HCl;2-iminopyrrolidine-hydrochloride;2-lminopyrrolidine hydrochloride;2-AMINO-1-PYRROLINE HYDROCHLORIDE
CBNumber: CB5848414
Molecular Formula: C4H9ClN2
Formula Weight: 120.58066
MOL File: 7544-75-4.mol

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2-Amino-1-pyrroline Hydrochloride Property

Melting point:: 171.0 to 175.0 °C
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystal
color: White to Almost white
InChI: InChI=1S/C4H8N2.ClH/c5-4-2-1-3-6-4;/h1-3H2,(H2,5,6);1H
InChIKey: JEBHLIYFPKISBI-UHFFFAOYSA-N
SMILES: C1(N)=NCCC1.Cl

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Safety

RIDADR: UN 1993 3/PG III
HazardClass: 3
PackingGroup: III
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2963
Product name: 2-Amino-1-pyrroline Hydrochloride
Purity: >98.0%(HPLC)(N)
Packaging: 1g
Price: $116
Updated: 2025/07/31

TRC

Product number: B525065
Product name: pyrrolidin-2-iminehydrochloride
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B525065
Product name: pyrrolidin-2-iminehydrochloride
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD142390
Product name: 3,4-Dihydro-2H-pyrrol-5-amine hydrochloride
Packaging: 5G
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-B0123
Product name: Pyrrolidin-2-iminehydrochloride
Purity: 99.77%
Packaging: 5g
Price: $87
Updated: 2021/12/16

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2-Amino-1-pyrroline Hydrochloride Chemical Properties,Usage,Production

Uses

2-Aminopyrrolidine hydrochloride is a heterocyclic organic compound that can be used as a pharmaceutical intermediate.

Synthesis

In a 250 mL bottomed flask, ammonia was bubbled into ethanol (80 mL) that was cooled to -78° C. for 45 min. The saturated solution that was obtained was transferred to a Parr autoclave, which contained 4-chlorobutanenitrile (60 g, 580 mmol). The mixture was stirred and heated to 120° C for 16 hr. The reaction mixture was cooled and transferred to a round-bottomed flask. The solvent was removed under reduced pressure to afford a yellow solid, which was washed with diethyl ether and dried under a high vacuum to afford an off-white solid 2-Amino-1-pyrroline Hydrochloride, 19.5 g, 232 mmol, 40percent yield. 1H NMR (DMSO-d6) δ 9.22 (br s, 1H), 8.93 (br s, 1H), 7.60 (br s, 1H), 3.52 (d, J=7.2 Hz, 2H), 2.76 (d. J=8.0 Hz, 2H), 2.08-1.96 (m, 2H).

References

[1] Patent: US2014/148461, 2014, A1. Location in patent: Paragraph 0354-0355

2-Amino-1-pyrroline Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-1-pyrroline Hydrochloride Suppliers

Americas 1 China 176 Europe 1 Germany 1 India 9 Japan 1 Switzerland 4 United Kingdom 1 United States 18 Global 212

Jinan XuanDe Chemical Co., Ltd.

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Hangzhou Sage Chemical Co., Ltd.

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View Lastest Price from 2-Amino-1-pyrroline Hydrochloride manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: 2-Amino-1-pyrroline Hydrochloride 7544-75-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1
Release date: 2025-08-28

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Aminopyrrolidine HCl; 2-AMINO-1-PYRROLINE HYDROCHLORIDE 7544-75-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Shanghai CRM New Material Technology Co., LTD

Product: 2-Amino-1-Pyrroline Hydrochloride 7544-75-4
Price: US $10.00-15.00/g
Min. Order: 10g
Purity: 99%
Supply Ability: 2546245
Release date: 2022-11-10

7544-75-4, 2-Amino-1-pyrroline HydrochlorideRelated Search:

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7544-75-4

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