ChemicalBook > CAS DataBase List > N-Phenylhydroxylamine
N-Phenylhydroxylamine
- Product Name
- N-Phenylhydroxylamine
- CAS No.
- 100-65-2
- Chemical Name
- N-Phenylhydroxylamine
- Synonyms
- NCI C-60093;N-HYDROXYANILINE;N-HYDROXYLANILINE;Hydroxyaminobenzene;Phenylhydroxylamine;N-Phenylhydroxyamine;N-Hydroxybenzenamine;N-Phenylhydroxylamin;N-Phenylhydroxylamine;BenzenaMine, N-hydroxy-
- CBNumber
- CB5851746
- Molecular Formula
- C6H7NO
- Formula Weight
- 109.13
- MOL File
- 100-65-2.mol
More
Less
N-Phenylhydroxylamine Property
- Melting point:
- 80-84℃
- Boiling point:
- 204.59°C (rough estimate)
- Density
- 1.1143 (rough estimate)
- refractive index
- 1.5444 (estimate)
- storage temp.
- -20°C
- pka
- 9.00±0.70(Predicted)
- form
- solid
- color
- Light brown
- Water Solubility
- 20g/L(5 ºC)
- Stability:
- Unstable - deteriorates with storage. Incompatible with strong oxidizing agents.
- EPA Substance Registry System
- Phenylhydroxylamine (100-65-2)
More
Less
Safety
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 45
- RIDADR
- UN 2811
- WGK Germany
- 3
- RTECS
- NC4900000
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2928009090
- Hazardous Substances Data
- 100-65-2(Hazardous Substances Data)
More
Less
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 671576
- Product name
- N-Phenylhydroxylamine
- Purity
- ≥97.0% (GC)
- Packaging
- 1g
- Price
- $107
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 671576
- Product name
- N-Phenylhydroxylamine
- Purity
- ≥97.0% (GC)
- Packaging
- 5g
- Price
- $307
- Updated
- 2024/03/01
Usbiological
- Product number
- 459603
- Product name
- N-Phenylhydroxylamine
- Packaging
- 1g
- Price
- $403
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 48242
- Product name
- N-Phenylhydroxylamine
- Packaging
- 1g
- Price
- $610
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0077183
- Product name
- N-PHENYLHYDROXYLAMINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $687.75
- Updated
- 2021/12/16
More
Less
N-Phenylhydroxylamine Chemical Properties,Usage,Production
Chemical Properties
tan powder or crystals
Uses
N-Phenylhydroxylamine can be used as a starting material for the synthesis of:
- 2-alkylindoles by treating with aliphatic terminal alkynes using gold catalyst via sequential 3,3-rearrangements and cyclodehydrations.
- Isoxazolidines by reacting with aldehydes and α, β-unsaturated aldehydes via a three-component one-pot catalytic reaction.
- Tetrahydro-1,2-oxazines by treating with an aldehyde and cyclopropane via homo 3+2 dipolar cycloaddition reaction.
Uses
Manufacture of cupferron.
Definition
ChEBI: N-phenylhydroxylamine is an N-substituted amine that is a derivative of aniline in which one of the amino hydrogen atoms is replaced with a hydroxy substituent.
Preparation
To a dispersion of 180 gm (2.75 gm-atom) of zinc dust in 500 ml of 50% aqueous ethanol, with vigorous stirring, is added 130 ml (156 gm, 1.27 mole) of nitrobenzene. The reaction is initiated by the dropwise addition of an aqueous ammonium chloride solution and can thereafter be maintained at a controllable rate by the cautious addition of the remaining ammonium chloride solution. The reaction temperature rises during this reduction step. Once reflux has subsided, the basic zinc salts are filtered off using a sintered glass funnel. The light green filtrate is cooled in an ice-salt mixture to precipitate the product. The yield is 100 gm (72.2%), m.p. 81°C.
The reduction of 2-methyl-2-nitropropane is carried out in a similar manner at 10-20°C to afford a 68% yield of N-t-butylhydroxylamine (m.p. 60-62°C).
General Description
Tan to brown crystals.
Air & Water Reactions
Soluble in hot water.
Reactivity Profile
N-Phenylhydroxylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Fire Hazard
Flash point data for N-Phenylhydroxylamine are not available but N-Phenylhydroxylamine is probably nonflammable.
Safety Profile
Poison by ingestion and subcutaneous routes. Human systemic effects by skin contact: primary irritation. Preparative hazard. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
Impure base deteriorates rapidly. Crystallise it from H2O, *C6H6 or *C6H6/pet ether (40-60o). The picrate has m 186o (from EtOH), and the benzenesulfonate salt has m 70o (dec )(EtOH/*C6H6). [Beilstein 15 H 2, 15 I 3, 15, II 4, 15 III 5. 15 IV 4.]
N-Phenylhydroxylamine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
N-Phenylhydroxylamine Suppliers
- Tel
- 021-50182298 021-50180596
- Fax
- +86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2210
- Advantage
- 55
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44751
- Advantage
- 61
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9984
- Advantage
- 60
- Tel
- 021-54306202 13764082696;
- info@hanhongsci.com
- Country
- China
- ProdList
- 42982
- Advantage
- 64
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12990
- Advantage
- 57
- Tel
- 0371-56632527 13838252817
- Fax
- 0371-56635027
- sales@kingsfine.com
- Country
- China
- ProdList
- 100
- Advantage
- 62
- Tel
- 021-33690831-8001 13552411790
- Fax
- 021-33690831
- postmaster@tyjchem.cn
- Country
- China
- ProdList
- 1542
- Advantage
- 55
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10269
- Advantage
- 58
- Tel
- info@aonanchem.com
- Country
- China
- ProdList
- 65
- Advantage
- 55
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9901
- Advantage
- 58
- Tel
- 18521735133 18521732826;
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25015
- Advantage
- 65
- Tel
- 400-1647117 15221909166
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41438
- Advantage
- 60
- Tel
- 021-54359730 400-008-9730
- Fax
- 021-54353864
- info@chemxyz.com
- Country
- China
- ProdList
- 3993
- Advantage
- 60
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 17982
- Advantage
- 56
- Tel
- 15523000485
- xingcanyaoye@sina.com
- Country
- China
- ProdList
- 1686
- Advantage
- 58
- Tel
- 15221275939 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15878
- Advantage
- 55
- Tel
- +86-571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 10015
- Advantage
- 53
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12357
- Advantage
- 58
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51471
- Advantage
- 80
- Tel
- 025-87193546 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 9030
- Advantage
- 60
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9709
- Advantage
- 58
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9604
- Advantage
- 55
- Tel
- 4009903999 13395398332
- Fax
- 0539-6365991
- sales@xiyashiji.com
- Country
- China
- ProdList
- 20810
- Advantage
- 60
- Tel
- 400-1166-196 18502815961
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 14623
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131981
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12308
- Advantage
- 58
- Tel
- 13127280945
- 285424065@qq.com
- Country
- China
- ProdList
- 9980
- Advantage
- 55
- Tel
- 10106090
- jjlchem2@163.com
- Country
- China
- ProdList
- 9986
- Advantage
- 58
- Tel
- 021-021-52271985 17721149837
- Fax
- +86 (21) 52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 19806
- Advantage
- 60
- Tel
- 025-66028182 18112977050
- Fax
- (3)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 15820
- Advantage
- 58
- Tel
- 400-400-1332688 18019345275
- Fax
- 400-133-2688
- amy@rhawn.cn
- Country
- China
- ProdList
- 15503
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 24971
- Advantage
- 58
- Tel
- 400-6387771-6038 18902104717
- sales@heowns.com
- Country
- China
- ProdList
- 20512
- Advantage
- 60
- Tel
- 400-400-400-9004166 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52712
- Advantage
- 58
- Tel
- 15971444841
- Fax
- 18327183813
- amber@biochempartner.com
- Country
- China
- ProdList
- 3063
- Advantage
- 58
- Tel
- +86-400-002-6226 13028896684
- sales@rrkchem.com
- Country
- China
- ProdList
- 55827
- Advantage
- 58
- Tel
- 0755-22202135 13316968096
- 1979313431@qq.com
- Country
- China
- ProdList
- 7692
- Advantage
- 58
- Tel
- +8619930503252
- Fax
- 86-0311-66562153
- daisy@crovellbio.com
- Country
- China
- ProdList
- 5964
- Advantage
- 58
- Tel
- 0551-65418671
- Fax
- 0551-65418697
- sales@tnjchem.com
- Country
- China
- ProdList
- 34572
- Advantage
- 58
- Tel
- 0371-63284658; 18135795563
- Fax
- QQ:2885349392
- 2885349392@qq.com
- Country
- China
- ProdList
- 9997
- Advantage
- 58
- Tel
- +86-023-61398051 +8613650506873
- sales@chemdad.com
- Country
- China
- ProdList
- 39916
- Advantage
- 58
- Tel
- 021-58380326 13585932672
- 3251669772@qq.com
- Country
- China
- ProdList
- 1073
- Advantage
- 58
- Tel
- 15021598081,571034478; 15021598081
- product001@xiushipharm.com
- Country
- China
- ProdList
- 4203
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44490
- Advantage
- 58
- Tel
- 027-59322316 15172518801
- Fax
- 027-59322316
- 1208480077@qq.com
- Country
- China
- ProdList
- 9944
- Advantage
- 58
- Tel
- 027-59503710 15172325309
- Fax
- 027-59503710
- 1400858877@qq.com
- Country
- China
- ProdList
- 9965
- Advantage
- 58
- Tel
- 021-4007787-550 400-7787-550
- 2850202386@qq.com
- Country
- China
- ProdList
- 10618
- Advantage
- 58
- Tel
- 400-1332688 18019345275
- Fax
- 400-133-2688
- amy@rhawn.cn
- Country
- China
- ProdList
- 1439
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39661
- Advantage
- 58
- Tel
- 15229059051
- 1027@dideu.com
- Country
- China
- ProdList
- 9941
- Advantage
- 58
More
Less
View Lastest Price from N-Phenylhydroxylamine manufacturers
Henan Fengda Chemical Co., Ltd
- Product
- N-Phenylhydroxylamine 100-65-2
- Price
- US $8.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-29
Career Henan Chemical Co
- Product
- N-Phenylhydroxylamine 100-65-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,100kg
- Release date
- 2019-07-04
100-65-2, N-PhenylhydroxylamineRelated Search:
1,2-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one
4,5-dihydro-a-(hydroxyMethyl)-a,3-diMethyl-5-oxo-1-phenyl-1H-Pyrazole-4-Methanesulfonic acid
BISPYRAZOLONE
Acetyl ketene
5-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
Ethyl (3E)-3-(2-phenylhydrazin-1-ylidene)butanoate
1H-Pyrazole,3-ethoxy-5-methyl-1-phenyl-(9CI)
Ethyl 3-[N-(phenyl)amino]-3-oxopropionate
Phenidone
NSC4751
Edaravone
benzenediazonium chloride
4,5-Dihydro-α,3-diMethyl-5-oxo-1-phenyl-α-sulfo-1H-pyrazole-4-acetic Acid
Edaravone iMpurity P3
3H-Pyrazol-3-one, 2,4-dihydro-4,4-bis(5-hydroxy-3-Methyl- 1-phenyl-1H-pyrazol-4-yl)-5-Methyl-2-phenyl-
3,3'-diMethyl-1,1'-diphenyl-1H,1'H-4,4'-bipyrazole-5,5'-diol
Edaravone Impurity 10
5-Ethoxy-3-methyl-1-phenylpyrazole