ChemicalBook > CAS DataBase List > Tributyrin

Tributyrin

Product Name
Tributyrin
CAS No.
60-01-5
Chemical Name
Tributyrin
Synonyms
GLYCEROL TRIBUTYRATE;GLYCERYL TRIBUTYRATE;C4:0;FEMA 2223;Glycerol tributanoate;BUTYRIN;C15H26O6;TRI-N-BUTYRIN;Butanoic acid, 1,2,3-propanetriyl ester;Kodaflex
CBNumber
CB5853942
Molecular Formula
C15H26O6
Formula Weight
302.36
MOL File
60-01-5.mol
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Tributyrin Property

Melting point:
-75 °C
Boiling point:
305 °C
Density 
1.0335
refractive index 
n20/D 1.435(lit.)
FEMA 
2223 | (TRI-)BUTYRIN
Flash point:
345 °F
storage temp. 
Store at RT.
solubility 
H2O: insoluble
form 
Liquid
color 
Clear colorless to yellow
Odor
at 100.00 %. cheese waxy creamy fatty
Odor Type
cheesy
biological source
synthetic
Water Solubility 
Not miscible in water.
Merck 
14,9620
JECFA Number
922
BRN 
1714746
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
UYXTWWCETRIEDR-UHFFFAOYSA-N
LogP
2.95
CAS DataBase Reference
60-01-5(CAS DataBase Reference)
EPA Substance Registry System
Tributyrin (60-01-5)
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Safety

Safety Statements 
24/25
WGK Germany 
1
RTECS 
ET7350000
TSCA 
Yes
HS Code 
29171900
Hazardous Substances Data
60-01-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W222322
Product name
Tributyrin
Purity
97%, FG
Packaging
1 unit
Price
$54.91
Updated
2025/07/31
Sigma-Aldrich
Product number
W222322
Product name
Tributyrin
Purity
97%, FG
Packaging
1 kg
Price
$130
Updated
2025/07/31
Sigma-Aldrich
Product number
W222322
Product name
Tributyrin
Purity
97%, FG
Packaging
5 kg
Price
$445
Updated
2025/07/31
Sigma-Aldrich
Product number
W222322
Product name
Tributyrin
Purity
97%, FG
Packaging
10 kg
Price
$588
Updated
2025/07/31
Sigma-Aldrich
Product number
91010
Product name
Glyceryl tributyrate
Purity
puriss., ≥98.5% (GC)
Packaging
25ml
Price
$89.3
Updated
2025/07/31
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Tributyrin Chemical Properties,Usage,Production

Description

Tributyrin (C15H26O6), also known as butyrin or glyceryl tributyrate, is the triester of glycerin and butyric acid. It is prepared by esterifcation of glycerin with excess butyric acid. Glycerol tributyrate has a characteristic odor and a bitter taste.

Chemical Properties

Tributyrin is a colorless, oily liquid with a bitter taste. It is soluble in alcohol and ether and fairly insoluble in water.

Uses

Tributyrin is a flavoring agent that is the triester of glycerin and butyric acid. it is prepared by esterification of glycerin with excess butyric acid. it is used in the following foods: baked goods; alcoholic beverages; nonalcoholic beverages; fats and oils; frozen dairy des- serts and mixes; gelatins, puddings and fillings; and soft candy. it is also termed butyrin and glyceryl tributyrate.

Preparation

Prepared by esterifcation of glycerol with excess butyric acid.

Production Methods

Tributyrin is manufactured via esterification of glycerol with butyric acid.

Definition

ChEBI: A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by butyric acid.

Taste threshold values

Taste characteristics at 30 ppm: bitter, waxy, fatty, cheese and butter nuances.

General Description

Tributyrin is a short-chain triacylglycerol that mainly occurs in butter. It shows potent anti-cancer property.

Safety Profile

Poison by intravenous route. Low toxicity by ingestion. Questionable carcinogen with experimental tumorigenic data. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.

Carcinogenicity

Administration of sodium butyrate in drinking water potentiates 1,2-dimethylhydrazine- induced colon cancer in rats . In mice, dietary administration of 5% tributyrin for 48 weeks did not lead to an increase in colonic tumor incidence or focal areas of dysplasia as compared to controls . Therefore, it has been suggested that the agent responsible for enhanced tumorigenesis in the rat study was sodium, rather than butyrate.

Tributyrin Preparation Products And Raw materials

Raw materials

Preparation Products

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Tributyrin Suppliers

Australia 2 Belgium 3 Canada 1 China 382 France 1 Germany 5 India 25 Japan 5 Switzerland 3 United Kingdom 12 United States 40 Global 479
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View Lastest Price from Tributyrin manufacturers

Wuhan JiyunZen Tech Co., Ltd.
Product
Tributyrin 60-01-5
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99% hplc
Supply Ability
500TONS
Release date
2025-05-07
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tributyrin 60-01-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
5000kg/month
Release date
2021-10-28
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Glyceryl tributyrate 60-01-5
Price
US $70.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-05-31

60-01-5, TributyrinRelated Search:

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