ChemicalBook > CAS DataBase List > pecazine

pecazine

Product Name
pecazine
CAS No.
60-89-9
Chemical Name
pecazine
Synonyms
Paxital;Pecatal;Lacumin;Mepazin;MEPAZINE;Pacazine;pecazine;Ai3-50131;Nothiazine;Einecs 200-490-8
CBNumber
CB5876419
Molecular Formula
C19H22N2S
Formula Weight
310.46
MOL File
60-89-9.mol
More
Less

pecazine Property

Melting point:
80°C
Boiling point:
bp4 230-235°
Density 
1.1252 (rough estimate)
refractive index 
1.6270 (estimate)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO : 130 mg/mL (418.73 mM; Need ultrasonic)
form 
Oil
color 
Light yellow to light brown
Water Solubility 
5.588mg/L(24 ºC)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
P218285
Product name
Pecazine
Packaging
100mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
287263
Product name
Pecazine
Packaging
10g
Price
$319
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012197
Product name
PECAZINE
Purity
95.00%
Packaging
5MG
Price
$503.06
Updated
2021/12/16
Matrix Scientific
Product number
176622
Product name
10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine
Packaging
100mg
Price
$990
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
71902
Product name
Pecazine
Packaging
1g
Price
$2200
Updated
2021/12/16
More
Less

pecazine Chemical Properties,Usage,Production

Originator

Pacatal,Warner Lambert,US,1957

Uses

Pecazine Hydrochloride acts as an anti-HIV agent in the form of C-C chemokine inhibitors.

Definition

ChEBI: Pecazine is a member of phenothiazines.

Manufacturing Process

A 500 cc flask equipped with a mechanical stirrer, reflux condenser and a soda-lime tube was filled with 230 cc of absolute xylene, 27.5 g of 1-methyl3-bromomethylpiperidine, 53.3 g of phenothiazine and 14.2 g of finely powdered sodium amide, and the solution was heated under reflux for 6 hours. After cooling water was added and the batch was extracted with ether. As the hydrochloric acid salt of the obtained phenothiazine derivative is difficultly soluble in water, the further processing was carried out by way of the acetate. The etheric solution was extracted several times in a separating funnel with dilute acetic acid. The combined aqueous extracts were basified, extracted with ether, dried with potassium carbonate and, after removal of the ether, distilled in vacuo.
Yield = 64%; boiling point 230°C to 235°C at 4 mm; melting point of hydrochloride is 180°C to 181°C.

Therapeutic Function

Tranquilizer

pecazine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

pecazine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2994
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7045
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57401
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32079
Advantage
58
VladaChem GmbH
Tel
+49-7246-3082843
Email
info@vladachem.de
Country
Germany
ProdList
1859
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58

60-89-9, pecazineRelated Search:


  • MEPAZINE
  • 10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine
  • Nothiazine
  • Paxital
  • pecazine
  • Pacazine
  • Pecatal
  • (N-Methyl-3-piperidyl)methylphenothiazine
  • 10-(1-Methyl-3-piperidyl)methyl phenothiazine
  • 10-(1-Methylpiperidyl-3-methyl)phenothiazine
  • 10H-Phenothiazine, 10-((1-methyl-3-piperidinyl)methyl)-
  • 2975-36-2 (Mono-hydrochloride)
  • Ai3-50131
  • Einecs 200-490-8
  • Lacumin
  • Mepazin
  • 10-[(1-Methylpiperidin-3-yl)methyl]phenothiazine
  • diffuse,B cell,inhibit,large,mucosa associated lymphoid tissue lymphoma translocation gene 1,MALT1,lymphoma,Mepazine,ABC-DLBCL,Apoptosis,Inhibitor
  • 60-89-9