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pecazine

Product Name
pecazine
CAS No.
60-89-9
Chemical Name
pecazine
Synonyms
Paxital;Pecatal;Lacumin;Mepazin;MEPAZINE;Pacazine;pecazine;Ai3-50131;Nothiazine;Einecs 200-490-8
CBNumber
CB5876419
Molecular Formula
C19H22N2S
Formula Weight
310.46
MOL File
60-89-9.mol
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pecazine Property

Melting point:
80°C
Boiling point:
bp4 230-235°
Density 
1.1252 (rough estimate)
refractive index 
1.6270 (estimate)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO : 130 mg/mL (418.73 mM; Need ultrasonic)
form 
Oil
color 
Light yellow to light brown
Water Solubility 
5.588mg/L(24 ºC)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P218285
Product name
Pecazine
Packaging
100mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
287263
Product name
Pecazine
Packaging
10g
Price
$319
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012197
Product name
PECAZINE
Purity
95.00%
Packaging
5MG
Price
$503.06
Updated
2021/12/16
Matrix Scientific
Product number
176622
Product name
10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine
Packaging
100mg
Price
$990
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
71902
Product name
Pecazine
Packaging
1g
Price
$2200
Updated
2021/12/16
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pecazine Chemical Properties,Usage,Production

Originator

Pacatal,Warner Lambert,US,1957

Uses

Pecazine Hydrochloride acts as an anti-HIV agent in the form of C-C chemokine inhibitors.

Definition

ChEBI: Pecazine is a member of phenothiazines.

Manufacturing Process

A 500 cc flask equipped with a mechanical stirrer, reflux condenser and a soda-lime tube was filled with 230 cc of absolute xylene, 27.5 g of 1-methyl3-bromomethylpiperidine, 53.3 g of phenothiazine and 14.2 g of finely powdered sodium amide, and the solution was heated under reflux for 6 hours. After cooling water was added and the batch was extracted with ether. As the hydrochloric acid salt of the obtained phenothiazine derivative is difficultly soluble in water, the further processing was carried out by way of the acetate. The etheric solution was extracted several times in a separating funnel with dilute acetic acid. The combined aqueous extracts were basified, extracted with ether, dried with potassium carbonate and, after removal of the ether, distilled in vacuo.
Yield = 64%; boiling point 230°C to 235°C at 4 mm; melting point of hydrochloride is 180°C to 181°C.

Therapeutic Function

Tranquilizer

pecazine Preparation Products And Raw materials

Raw materials

Preparation Products

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pecazine Suppliers

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60-89-9, pecazineRelated Search:


  • MEPAZINE
  • 10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine
  • Nothiazine
  • Paxital
  • pecazine
  • Pacazine
  • Pecatal
  • (N-Methyl-3-piperidyl)methylphenothiazine
  • 10-(1-Methyl-3-piperidyl)methyl phenothiazine
  • 10-(1-Methylpiperidyl-3-methyl)phenothiazine
  • 10H-Phenothiazine, 10-((1-methyl-3-piperidinyl)methyl)-
  • 2975-36-2 (Mono-hydrochloride)
  • Ai3-50131
  • Einecs 200-490-8
  • Lacumin
  • Mepazin
  • 10-[(1-Methylpiperidin-3-yl)methyl]phenothiazine
  • diffuse,B cell,inhibit,large,mucosa associated lymphoid tissue lymphoma translocation gene 1,MALT1,lymphoma,Mepazine,ABC-DLBCL,Apoptosis,Inhibitor
  • Mepazine, 10 mM in DMSO
  • 60-89-9