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2-methoxypropionic acid

Product Name
2-methoxypropionic acid
CAS No.
4324-37-2
Chemical Name
2-methoxypropionic acid
Synonyms
2021.11.2;UNII:288B9CW12D;Einecs 224-356-3;2-Methoxypropionsure;2-methoxypropanoic acid;2-methoxypropionic acid;Propanoic acid, 2-methoxy-;alpha-Methoxypropionic acid;2-methoxypropanoic acid(SALTDATA: FREE)
CBNumber
CB5915226
Molecular Formula
C4H8O3
Formula Weight
104.1
MOL File
4324-37-2.mol
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2-methoxypropionic acid Property

Melting point:
128.5 °C
Boiling point:
199℃
Density 
1.085
Flash point:
87℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
pka
3.59±0.10(Predicted)
color 
Colorless
InChI
InChI=1S/C4H8O3/c1-3(7-2)4(5)6/h3H,1-2H3,(H,5,6)
InChIKey
ICPWFHKNYYRBSZ-UHFFFAOYSA-N
SMILES
C(O)(=O)C(OC)C
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M267198
Product name
2-Methoxypropanoicacid
Packaging
500mg
Price
$75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0000300
Product name
2-METHOXYPROPANOIC ACID
Purity
95.00%
Packaging
1G
Price
$513
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0000300
Product name
2-METHOXYPROPANOIC ACID
Purity
95.00%
Packaging
2.5G
Price
$625
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0000300
Product name
2-METHOXYPROPANOIC ACID
Purity
95.00%
Packaging
5G
Price
$758
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
33655
Product name
2-Methoxypropanoicacid
Purity
96%
Packaging
5G
Price
$990
Updated
2021/12/16
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2-methoxypropionic acid Chemical Properties,Usage,Production

Synthesis

124-41-4

598-72-1

4324-37-2

A methanolic solution of 25% sodium methanolate (16 mL) was slowly added dropwise to a stirring solution of 2-bromopropionic acid (19.6 mmol) in methanol (5 mL) under nitrogen protection. The reaction mixture was heated and reacted at 50 °C overnight while continuously protected by the passage of nitrogen. Upon completion of the reaction, the reaction solution was concentrated under reduced pressure by rotary evaporator. The residue was adjusted to pH 1 with aqueous 1N hydrochloric acid, followed by three extractions with ethyl acetate (70 mL, 25 mL, 10 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated again under reduced pressure to afford 2-methoxypropionic acid as a colorless oil in the yield of 2.04 g (99% yield), which was pure enough to be used directly in the subsequent reaction without further purification. The product was characterized by 1H NMR (CD3OD): δ 3.67 (q, 1H), 3.33 (s, 3H), 1.33 ppm (d, 3H).

References

[1] Patent: WO2006/96338, 2006, A1. Location in patent: Page/Page column 41
[2] Patent: WO2006/133006, 2006, A2. Location in patent: Page/Page column 46-47
[3] Australian Journal of Chemistry, 1980, vol. 33, # 4, p. 809 - 821
[4] Organic Letters, 2018, vol. 20, # 16, p. 4867 - 4870
[5] Patent: KR2015/128789, 2015, A. Location in patent: Paragraph 0896; 0898; 0899

2-methoxypropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-methoxypropionic acid Suppliers

ShangHai ZiCheng Med-Pharm Technology Company Ltd.
Tel
021-56710790 18721468858
Fax
021-64228193
Email
wangyh@fudan.edu.cn
Country
China
ProdList
26
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Santai Labs, Inc.
Tel
519-85601385
Fax
+86 519 8560 1389
Email
marketing@santailabs.com
Country
China
ProdList
891
Advantage
62
Atop-Pharma (Shanghai) Technology Co., Ltd.
Tel
+86 (21) 5196-9732
Fax
+86 (21) 5196-9733
Country
China
ProdList
996
Advantage
57
Changzhou Wanyao Biotechnology Co., Ltd.
Tel
0519-89185693 15312551983
Fax
0519-89185693
Email
2410037592@qq.com
Country
China
ProdList
261
Advantage
55
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View Lastest Price from 2-methoxypropionic acid manufacturers

Career Henan Chemical Co
Product
2-methoxypropionic acid 4324-37-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-25