ChemicalBook > CAS DataBase List > 4,4'-propylenebis(piperazine-2,6-dione)

4,4'-propylenebis(piperazine-2,6-dione)

Product Name
4,4'-propylenebis(piperazine-2,6-dione)
CAS No.
21416-67-1
Chemical Name
4,4'-propylenebis(piperazine-2,6-dione)
Synonyms
Troxozone;RAZOXANUM;Propyliminum;rac-Dexrazoxane;4,4'-(Propane-1,2-diyl);bis(piperazine-2,6-dione);-propylenebis(piperazine-2,6-dione);4,4'-propylenebis(piperazine-2,6-dione);4,4'-Propane-1,2-diyldipiperazine-2,6-dione;4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
CBNumber
CB5918838
Molecular Formula
C11H16N4O4
Formula Weight
268.27
MOL File
21416-67-1.mol
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4,4'-propylenebis(piperazine-2,6-dione) Property

Melting point:
237-239°
Boiling point:
411.43°C (rough estimate)
Density 
1.2576 (rough estimate)
refractive index 
1.6081 (estimate)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: soluble40mg/mL
form 
solid
pka
11.00±0.20(Predicted)
color 
White to off-white
Water Solubility 
3g/L(25 ºC)
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Safety

WGK Germany 
3
RTECS 
TL6389900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R8657
Product name
Razoxane
Purity
>98% (HPLC)
Packaging
5mg
Price
$112
Updated
2024/03/01
TRC
Product number
R128060
Product name
Razoxane
Packaging
1g
Price
$715
Updated
2021/12/16
Matrix Scientific
Product number
076182
Product name
4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
Purity
95+%
Packaging
250mg
Price
$907
Updated
2021/12/16
AK Scientific
Product number
E393
Product name
Razoxane
Packaging
1g
Price
$1063
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008266
Product name
RAZOXANE
Purity
95.00%
Packaging
1G
Price
$1575
Updated
2021/12/16
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4,4'-propylenebis(piperazine-2,6-dione) Chemical Properties,Usage,Production

Uses

Razoxane is an inhibitor of Topo II.

Definition

ChEBI: Razoxane is a N-alkylpiperazine.

Safety Profile

Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

4,4'-propylenebis(piperazine-2,6-dione) Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-propylenebis(piperazine-2,6-dione) Suppliers

China 31 Germany 1 India 1 United States 7 Global 40
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

21416-67-1, 4,4'-propylenebis(piperazine-2,6-dione) Related Search:

polyethyleneimine Dexrazoxane Ethyl dimorpholine

  • 4,4'-propylenebis(piperazine-2,6-dione)
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • RAZOXANUM
  • 4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
  • 4,4'-Propane-1,2-diyldipiperazine-2,6-dione
  • Propyliminum
  • 4-[3-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
  • 4,4'-(Propane-1,2-diyl)
  • bis(piperazine-2,6-dione)
  • Troxozone
  • -propylenebis(piperazine-2,6-dione)
  • 4,4'-propylenebis(piperazine-2,6-dione) USP/EP/BP
  • 4,5,9,10-Pyrenetetrone,2,7-bis(1,6-dimethylethyl)-
  • rac-Dexrazoxane
  • ICRF 159,ICRF159,ICRF-159,Topoisomerase II Inhibitor,Razoxane,RCC,Inhibitor,Topoisomerase,renal cell carcinoma,inhibit
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • 21416-67-1
  • Angiogenesis and metastasis.