ChemicalBook > CAS DataBase List > 4,4'-propylenebis(piperazine-2,6-dione)

4,4'-propylenebis(piperazine-2,6-dione)

Product Name
4,4'-propylenebis(piperazine-2,6-dione)
CAS No.
21416-67-1
Chemical Name
4,4'-propylenebis(piperazine-2,6-dione)
Synonyms
Troxozone;RAZOXANUM;Propyliminum;rac-Dexrazoxane;4,4'-(Propane-1,2-diyl);bis(piperazine-2,6-dione);-propylenebis(piperazine-2,6-dione);4,4'-propylenebis(piperazine-2,6-dione);4,4'-Propane-1,2-diyldipiperazine-2,6-dione;4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
CBNumber
CB5918838
Molecular Formula
C11H16N4O4
Formula Weight
268.27
MOL File
21416-67-1.mol
More
Less

4,4'-propylenebis(piperazine-2,6-dione) Property

Melting point:
237-239°
Boiling point:
411.43°C (rough estimate)
Density 
1.2576 (rough estimate)
refractive index 
1.6081 (estimate)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO: soluble40mg/mL
form 
solid
pka
11.00±0.20(Predicted)
color 
White to off-white
Water Solubility 
3g/L(25 ºC)
More
Less

Safety

WGK Germany 
3
RTECS 
TL6389900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R8657
Product name
Razoxane
Purity
>98% (HPLC)
Packaging
5mg
Price
$112
Updated
2024/03/01
TRC
Product number
R128060
Product name
Razoxane
Packaging
1g
Price
$715
Updated
2021/12/16
Matrix Scientific
Product number
076182
Product name
4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
Purity
95+%
Packaging
250mg
Price
$907
Updated
2021/12/16
AK Scientific
Product number
E393
Product name
Razoxane
Packaging
1g
Price
$1063
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008266
Product name
RAZOXANE
Purity
95.00%
Packaging
1G
Price
$1575
Updated
2021/12/16
More
Less

4,4'-propylenebis(piperazine-2,6-dione) Chemical Properties,Usage,Production

Uses

Razoxane is an inhibitor of Topo II.

Definition

ChEBI: Razoxane is a N-alkylpiperazine.

Safety Profile

Suspected human carcinogen producing leukemia and skin tumors. Moderately toxic by intraperitoneal route. Human effects: normocytic anemia and thrombocytopenia. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

4,4'-propylenebis(piperazine-2,6-dione) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4,4'-propylenebis(piperazine-2,6-dione) Suppliers

China 31 Germany 1 India 1 United States 7 Global 40
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58

21416-67-1, 4,4'-propylenebis(piperazine-2,6-dione) Related Search:

polyethyleneimine Dexrazoxane Ethyl dimorpholine

  • 4,4'-propylenebis(piperazine-2,6-dione)
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • RAZOXANUM
  • 4,4'-(1-Methylethylene)bis(2,6-piperazinedione)
  • 4,4'-Propane-1,2-diyldipiperazine-2,6-dione
  • Propyliminum
  • 4-[3-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
  • 4,4'-(Propane-1,2-diyl)
  • bis(piperazine-2,6-dione)
  • Troxozone
  • -propylenebis(piperazine-2,6-dione)
  • 4,4'-propylenebis(piperazine-2,6-dione) USP/EP/BP
  • 4,5,9,10-Pyrenetetrone,2,7-bis(1,6-dimethylethyl)-
  • rac-Dexrazoxane
  • ICRF 159,ICRF159,ICRF-159,Topoisomerase II Inhibitor,Razoxane,RCC,Inhibitor,Topoisomerase,renal cell carcinoma,inhibit
  • 4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione)
  • 21416-67-1
  • Angiogenesis and metastasis.