ChemicalBook > CAS DataBase List > (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol

Product Name
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
CAS No.
209414-27-7
Chemical Name
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
Synonyms
Efavirenz IP Imp E;Efavirenz USP RC A;Efavirenz Impurity 5;Efavirenz IP Impurity E;Efavirenz Related CoMpound A;Efavirenz USP Related Compound A;(S)-2-(2-Amino-5-chlorophenyl)-4-cy;Efavirenz Impurity 5(Efavirenz IP Impurity E);(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopr...;(S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol
CBNumber
CB5948781
Molecular Formula
C13H11ClF3NO
Formula Weight
289.68
MOL File
209414-27-7.mol
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(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Property

Melting point:
134-136°C
Boiling point:
425.1±45.0 °C(Predicted)
Density 
1.46
storage temp. 
2-8°C(protect from light)
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
9.13±0.24(Predicted)
color 
White to Off-White
InChIKey
KEMUGFRERPPUHB-LBPRGKRZSA-N
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Safety

HS Code 
2922199695
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2068
Product name
Efavirenz Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50mg
Price
$503.3
Updated
2025/07/31
Sigma-Aldrich
Product number
1234125
Product name
Efavirenz Related Compound A
Packaging
20mg
Price
$1060
Updated
2025/07/31
TRC
Product number
A603765
Product name
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
Packaging
250mg
Price
$185
Updated
2021/12/16
TRC
Product number
A603765
Product name
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
Packaging
2.5g
Price
$1065
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA76672
Product name
(S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol
Packaging
10mg
Price
$55
Updated
2021/12/16
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(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of Efavirenz (E425000) impurity.

(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol Suppliers

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View Lastest Price from (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol manufacturers

Henan Fengda Chemical Co., Ltd
Product
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 209414-27-7
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-27
Career Henan Chemical Co
Product
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 209414-27-7
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-18
Career Henan Chemical Co
Product
(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 209414-27-7
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-18

209414-27-7, (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-olRelated Search:

Glycine 6-Aminocaproic acid Cyclopropyl methyl ketone ALTRENOGEST Lithium diisopropylamide 3-Aminophenol 3-Chloropropyne Chlorodimethylphenylsilane 3-Methyl-2-butanone Propargyl bromide Tris(hydroxymethyl)aminomethane Efavirenz (S)-5-chloro-a-(Cyclopropylacetenyl)-2-[((4-methoxyphenyl)methyl)amino]-a- (trifluoromethyl) benzenemethanol (E-4) rac 8,14-Dihydroxy Efavirenz rac 8-Hydroxy Efavirenz Efavirenz Related Compound B (15 mg) ((S,E)-6-Chloro-4-(2-Cyclopropylvinyl)-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one) Efavirenz IP Impurity A rac 7-Hydroxy Efavirenz

  • BenzeneMethanol,2-aMino-5-chloro-a-(2-cyclopropylethynyl)-a-(trifluoroMethyl)-, (aS)-
  • (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol
  • Efavirenz Impurity 5(Efavirenz IP Impurity E)
  • (2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol
  • Efavirenz IP Imp E
  • (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol (E05)
  • (2R)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
  • (R)-2-(2-Amino-5-chloro-phenyl)-4-cyclopropyl-1,1,1-trifluoro-but-3-yn-2-ol
  • (S)-5-Chloro-Alpha-(Cyclopropylethynyl)-2-Amino-Alpha-(Trifluoromethyl)-Benzenemethanol
  • (S)-1-(2-AMINO-5-CHLOROPHENYL)-1-(TRIFLUOROMETHYL)-3-CYCLOPROPYL-2-PROPYN-1-OL
  • (S)-5-CHLORO-A-(CYCLOPROPYLETHYNYL)-2-AMINO-A-(TRIFLUOROMETHYL)BENZENE METHANOL
  • Efavirenz Related Compound A (20 mg) ((S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol)
  • (2S)-2-(2-aMino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
  • Efavirenz Related CoMpound A
  • (S)-1-(2-AMino-5-chlorophenyl)-1-(trifluoroMethyl)-3-cyclopropyl-2-propyn-1-ol (E6)
  • 1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
  • (S)-5-Chloro-Alpha-(Cyclopropylethynyl-2-Amino-Alpha-(Triflumethanolmethyl)-Benzenemethanol
  • Efavirenz USP Related Compound A
  • (S)-2-(2-Amino-5-chlorophenyl)-4-cy
  • Efavirenz IP Impurity E
  • Benzenemethanol, 2-amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)-, (αS)-
  • Efavirenz Impurity 5
  • (S)-1-(2-AMINO-5-CHLOROPHENYL)-1-(TRIFLUOROMETHYL)-3-CYCLOPROPYL-2-PROPYN-1-OL (E05) CAS 209414-27-7
  • Efavirenz USP RC A
  • Efavirenz Related Compound A/ Efavirenz IP Impurity E (Efavirenz Amino Alcohol/ Efavirenz amino carbinol)
  • (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopr...
  • Efavirenz Related Compound A ((S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn- (1234125)
  • (αS)-2-Amino-5-chloro-α-(2-cyclopropylethynyl)-α-(trifluoromethyl)benzenemethanol
  • (S)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
  • (S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol 98%
  • Efavirenz Impurity: (S)-2-(2-Amino-5-Chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
  • (alphaS)-2-Amino-5-chloro-alpha-(2-cyclopropylethynyl)-alpha-(trifluoromethyl)-benzenemethanol
  • 209414-27-7