Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)

Product Name: Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
CAS No.: 176199-48-7
Chemical Name: Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
Synonyms: LY 354740;Eglumetad;Eglumegad;(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S...;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid,2-amino-,(1S,2S,5R,6S)-;Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-aMino-, [1S-(1a,2b,5a,6a)]-;Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)
CBNumber: CB61042715
Molecular Formula: C8H11NO4
Formula Weight: 185.18
MOL File: 176199-48-7.mol

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Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Property

Melting point:: 270-271 °C
Boiling point:: 376.4±32.0 °C(Predicted)
Density: 1.569
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: H2O : 6.33 mg/mL (34.18 mM; Need ultrasonic and warming)
form: Powder
pka: 2.06±0.40(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.04685
Product name: LY 354740 - CAS 176199-48-7 - Calbiochem
Packaging: 10MG
Price: $156
Updated: 2022/05/15

Cayman Chemical

Product number: 24215
Product name: LY354740
Purity: ≥95%
Packaging: 1mg
Price: $33
Updated: 2024/03/01

Cayman Chemical

Product number: 24215
Product name: LY354740
Purity: ≥95%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 24215
Product name: LY354740
Purity: ≥95%
Packaging: 10mg
Price: $160
Updated: 2024/03/01

Tocris

Product number: 3246
Product name: LY354740
Purity: ≥98%(HPLC)
Packaging: 10
Price: $208
Updated: 2021/12/16

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Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Chemical Properties,Usage,Production

Uses

Treatment ofgeneral anxiety disorders and smoking cessation (metabotropic glutamate agonist).

Uses

LY 354740 is a highly selective and potent agonist of group II mGluR.

Definition

ChEBI: Eglumetad is a L-alpha-amino acid.

Biological Activity

Highly selective and potent agonist of group II mGlu receptors (EC 50 values are 5.1 and 24.3 nM at mGlu 2 and mGlu 3 receptors respectively and > 100000 nM at mGlu 4 , mGlu 7 , mGlu 1a and mGlu 5a receptors). Displays antianxiety and antiaddictive activity in vivo . Orally and systemically active.

storage

+4°C

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) Suppliers

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176199-48-7, Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)Related Search:

DL-ALPHA-AMINOPIMELIC ACID Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI) L-Cyclopropylglycine L-2-Aminoadipic acid (S)-1-CYCLOPROPYLETHYLAMINE Cycloleucine (2S,1'S,2'S)-2-(CARBOXYCYCLOPROPYL)GLYCINE DL-2-METHYLGLUTAMIC ACID 1-Amino-1-cyclohexanecarboxylic acid AMINO-CYCLOPROPYL-ACETIC ACID DL-ALPHA-AMINOSUBERIC ACID D-ALPHA-AMINOSUBERIC ACID H-ALPHA-ME-LEU-OH CHEMBRDG-BB 6156098 cis-1,3-cyclohexanedicarboxylic acid 1-AMINO-3-METHYLCYCLOHEXANECARBOXYLIC ACID TALAGLUMETAD 2-AMINO-2-CYCLOPROPYLPROPIONIC ACID

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S,5R,6S)- (9CI)

Eglumegad

Eglumetad

LY 354740

(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Bicyclo[3.1.0]hexane-2,6-dicarboxylicacid, 2-aMino-, [1S-(1a,2b,5a,6a)]-

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid,2-amino-,(1S,2S,5R,6S)-

Bicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 2-amino-, (1S,2S...

176199-48-7

CYCLOPENTANE

Glutamate