ChemicalBook > CAS DataBase List > 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

Product Name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
CAS No.
86393-33-1
Chemical Name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Synonyms
Q-ACID;Fluoroquinolonic acid;FLUOROQUINOLONE;7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID;AKOS 1131;Q.Acid levo;1-Ciprofloxacin;Ciprofloxacin -1;Fluorchinolonsure;TIMTEC-BB SBB003016
CBNumber
CB6111667
Molecular Formula
C13H9ClFNO3
Formula Weight
281.67
MOL File
86393-33-1.mol
More
Less

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Property

Melting point:
242-245 °C(lit.)
Boiling point:
467.3±45.0 °C(Predicted)
Density 
1.652±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
6.36±0.41(Predicted)
color 
Off-White to Light Yellow
InChIKey
ISPVACVJFUIDPD-UHFFFAOYSA-N
CAS DataBase Reference
86393-33-1(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-52/53
Safety Statements 
26-36-61-22
WGK Germany 
2
RTECS 
VB1993795
HazardClass 
IRRITANT
HS Code 
29334900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1174
Product name
Fluoroquinolonic acid
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500mg
Price
$126
Updated
2024/03/01
Sigma-Aldrich
Product number
1278302
Product name
Fluoroquinolonic acid
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
150mg
Price
$1380
Updated
2024/03/01
TCI Chemical
Product number
C2293
Product name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$39
Updated
2024/03/01
TCI Chemical
Product number
C2293
Product name
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
C2190050
Product name
Ciprofloxacin impurity A
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
c2190050
Price
$153
Updated
2024/03/01
More
Less

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Powder

Uses

An intermediate in the synthesis of Ciprofloxacin, a fluorinated quinolone antibacterial

Uses

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.

General Description

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, also known as fluoroquinolonic acid, can be prepared from ethyl 2,4-dichloro-5-fluorobenzoylacetate. It is formed as an intermediate during the synthesis of ciprofloxacin hydrochloride, a fluorinated quinolone antibacterial drug.

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Cyhalothrin
More
Less

7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid Suppliers

Americas 1 Belgium 2 Canada 4 China 217 Europe 2 France 1 Germany 5 India 55 Japan 3 Russia 1 Slovakia 1 South Korea 1 Switzerland 3 Ukraine 1 United Kingdom 15 United States 51 Global 363
-Binhai Golden Hilen Medicine Chemistry Co., Ltd.
Tel
0515-84383887 13777682051
Email
jhl@jhlchem.com
Country
China
ProdList
1
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Shanghai Nuohey Chemical Co., Ltd.
Tel
021-52212593 13761626812
Fax
+86 (21) 51062076
Email
sales@nuohey.com
Country
China
ProdList
10690
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2893
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Runpharm Technology Limited
Tel
18171398856 2968382473
Fax
0086-21-50758330
Email
service@runpharm.com
Country
China
ProdList
718
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
TargetMol Chemicals Inc.
Tel
021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7934
Advantage
58
Shanghai Huikai Chemical Technology Co., Ltd.
Tel
021-61995394 18916691159
Email
chemicalsea@163.com
Country
China
ProdList
1975
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7892
Advantage
56
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13358
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9664
Advantage
58
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.
Tel
027-59420981,18702770802
Fax
027-83322098
Country
China
ProdList
1975
Advantage
50
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2984
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7715
Advantage
55
SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
QQ:2746983436
Email
sales@sano-chem.com
Country
China
ProdList
3929
Advantage
55
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7996
Advantage
55
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
Nanjing XiLang Chemical Products Co., Ltd.
Tel
025-5276156 18936048580
Email
chemxilang@163.com
Country
China
ProdList
4011
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9604
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
More
Less

View Lastest Price from 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid manufacturers

Guangzhou PI PI BIOTECH INC
Product
Ciprofloxacin Impurity A (EP) 86393-33-1
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
90%+
Supply Ability
10g
Release date
2020-06-04
Henan Fengda Chemical Co., Ltd
Product
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4 86393-33-1
Price
US $8.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-29
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid 86393-33-1
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2020-09-28

86393-33-1, 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidRelated Search:

Chloromethyl isopropyl carbonate Ethyl 2-(Chlorosulfonyl)acetate Clioquinol Ciprofloxacin Allyl chloride Cyromazine Propiconazole Ciprofloxacin hydrochloride Tetrapropylammonium hydroxide 5,6,7,8-TETRAHYDROISOQUINOLINE Dihydromyrcenol 3-Chloropropyltrichlorosilane 7-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 3-METHOXYPROPIONIC ACID Stearic acid Ciprofloxacin lactate Glycine Citric acid

  • TIMTEC-BB SBB003016
  • 1-CYCLOPROPYL-7-CHLORO-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLONE-3-CARBOXYLIC ACID
  • 1-CYCLOPROPYL-6-FLUORO-7-CHLORO-1,4-DIHYDRO-4-OXO-3-QUINOLINIC CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-1,4-DIHYDRO-6-FLUOROQUINOL-4-ONE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOHYDROQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXYHYDROQUINOLINE-3-CARBOXYLIC ACID
  • 7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID
  • 7-CHLORO-6-FLUORO-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • AKOS 1131
  • 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-oxoquinoline-3-Carboxylate
  • 1-Ciprofloxacin
  • 7-CHLORO1-CYCLOPROPYL-6-FLUORO-1,4-DIHYD
  • FLUOROQUINOLONE
  • 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro 4-Oxoquinoline Carboxylic Acid
  • Chloro-1-cycloproyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinoline-3-carboxylicAcid
  • Fluoroquinolonic acid
  • FLUOROQUINOLONEACID
  • Fluorchinolonsure
  • 7-Chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-3-quinolinecarboxylic aci
  • 3-QUINOLINECARBOXYLICACID,7-CHLORO-1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO
  • 7-CHLORO-6-FLUORO-4-OXO-N-CYCLOPROPYL-1,4-DIHYDROQUINOLINE CARBOXYLIC ACID
  • Ciprofloxacin -1
  • 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-3-quinolinecarboxylicaci
  • 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylicacid
  • Ciprofloxacin impurity A (EP)
  • 7-Chloro-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-3-Quinoline Carboxylic Acid (Q Acid)
  • Ciprofloxacin Impurity 1(Ciprofloxacin EP Impurity A)
  • Enrofloxacin Impurity 1(Enrofloxacin EP Impurity A)
  • 7-chloro-1-cyclopropyl-6-fluoro-4-oxo
  • Ciprofloxacin Hydrochloride Impurity Ⅰ:Ciprofloxacin EP Impurity A
  • Ciprofloxacin ImpuritⅠ:(Ciprofloxacin Impurity A)7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
  • Q.Acid levo
  • Q-ACID
  • Q-ACID, 7-CHLORO-1-CYCLOPROPYL-6-FLUORO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
  • Fluoroquinolonic acid, Q-Acid
  • 3-Quinolinecarboxylic acid, 1,4-dihydro-7-chloro-1-cyclopropyl-6-fluoro-4-oxo-
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid,98%
  • 7-Chloro-6-fluoro-1-cyclopropyl-1
  • 7-Chloro-6-fluoro-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acid（Q-acid ）
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid,Fluoroquinolonic acid, Q-Acid
  • Fluoroquinolonic Acid (50 mg)
  • Fluoroquinolonic Acid (150 mg)
  • 1-Cyclopropyl-1,4-dihydro-4-oxo-6-fluoro-7-chloro-3-quinolinecarboxylic Acid
  • 7-Chloro-1-cyclopropyl-6-fluoro-3-carboxy-1,4-dihydro-4-oxoquinoline
  • Ciprofloxacin EP IMpurity A
  • Ciprofloxacin impurity A (PhEur)
  • Ciprofloxacin Related Compound A (USP)
  • 3-Carboxy-7-chloro-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxoquinoline, (3-Carboxy-7-chloro-6-fluoro-4-oxoquinolin-1(4H)-yl)cyclopropane
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-0x0quinoline-3-carboxylic acid
  • 7-Chloro-1-CP-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid
  • Ciprofloxacin impurity A CRS
  • 7-Chloro-1-cyclopropyl-6-fluoro-4-o
  • 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic Acid &gt
  • Fluoroquinolonic acid A