2-Bromo-3-methoxy-6-nitropyridine
- Product Name
- 2-Bromo-3-methoxy-6-nitropyridine
- CAS No.
- 76066-07-4
- Chemical Name
- 2-Bromo-3-methoxy-6-nitropyridine
- Synonyms
- 2-Bromo-3-methoxy-6-nitropyridine;6-Bromo-5-methoxy-2-nitropyridine;Pyridine, 2-bromo-3-methoxy-6-nitro-;2-Bromo-3-methoxy-6-nitropyridine ISO 9001：2015 REACH
- CBNumber
- CB61175628
- Molecular Formula
- C6H5BrN2O3
- Formula Weight
- 233.02
- MOL File
- 76066-07-4.mol
2-Bromo-3-methoxy-6-nitropyridine Property
- Melting point:
- 140-1420C
- Boiling point:
- 364.4±37.0 °C(Predicted)
- Density
- 1.730±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -10.90±0.10(Predicted)
- color
- White to Off-White
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B684790
- Product name
- 2-Bromo-3-methoxy-6-nitropyridine
- Packaging
- 100mg
- Price
- $225
- Updated
- 2021/12/16
- Product number
- B2860-46
- Product name
- 2-Bromo-3-methoxy-6-nitropyridine
- Packaging
- 50mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- 129768
- Product name
- 2-Bromo-3-methoxy-6-nitro-pyridine
- Purity
- 95%+
- Packaging
- 1g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- FB19123
- Product name
- 2-Bromo-3-methoxy-6-nitropyridine
- Packaging
- 2g
- Price
- $450
- Updated
- 2021/12/16
- Product number
- FB19123
- Product name
- 2-Bromo-3-methoxy-6-nitropyridine
- Packaging
- 5G
- Price
- $650
- Updated
- 2021/12/16
2-Bromo-3-methoxy-6-nitropyridine Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Synthesis
24100-18-3
76066-07-4
General procedure for the synthesis of 2-bromo-3-methoxy-6-nitropyridine from 2-bromo-3-methoxypyridine: 2-bromo-3-methoxypyridine (4.45 g, 23.7 mmol) was slowly added to a mixture of fuming nitric acid and concentrated sulfuric acid (1:1, v/v, total of 18 mL) that had been pre-cooled to 0 °C. The reaction mixture was kept stirred at 55 °C for 1.5 hours. Upon completion of the reaction, the mixture was carefully poured into ice water (150 mL) and a precipitate was immediately generated. The resulting precipitate was the target product 2-bromo-3-methoxy-6-nitropyridine, which could be used in the subsequent reaction without further purification. Yield: 3.54 g (64%) as a light yellow solid.1H NMR (DMSO-d6, 400 MHz) δ 8.41 (d, 1H), 7.80 (d, 1H), 4.06 (s, 3H).
References
[1] Journal of Medicinal Chemistry, 2009, vol. 52, # 3, p. 637 - 645
[2] Tetrahedron, 1986, vol. 42, # 5, p. 1475 - 1485
[3] Pharmazie, 2000, vol. 55, # 12, p. 907 - 912
[4] Journal of Medicinal Chemistry, 1981, vol. 24, # 1, p. 39 - 42
[5] Patent: WO2007/51981, 2007, A1. Location in patent: Page/Page column 56
2-Bromo-3-methoxy-6-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-3-methoxy-6-nitropyridine Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
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- 6100
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View Lastest Price from 2-Bromo-3-methoxy-6-nitropyridine manufacturers
- Product
- 2-Bromo-3-methoxy-6-nitropyridine 76066-07-4
- Price
- US $1.00-1.00/Kg/Drum
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 50tons
- Release date
- 2020-05-12
- Product
- 2-Bromo-3-methoxy-6-nitropyridine 76066-07-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-08
- Product
- 2-Bromo-3-methoxy-6-nitropyridine 76066-07-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-31