Pimonidazole
- Product Name
- Pimonidazole
- CAS No.
- 70132-50-2
- Chemical Name
- Pimonidazole
- Synonyms
- NSC 380540;Pimonidazole;Pimonidazole USP/EP/BP;inhibit,Pimonidazole,Inhibitor;1-(2-nitroimidazol-1-yl)-3-piperidin-1-ylpropan-2-ol;alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;α-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol;1-Piperidineethanol, α-[(2-nitro-1H-imidazol-1-yl)methyl]-;1-(2-Nitro-1H-imidazol-1-yl)-3-(piperidin-1-yl)-2-propanol;alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
- CBNumber
- CB61179505
- Molecular Formula
- C11H18N4O3
- Formula Weight
- 254.29
- MOL File
- 70132-50-2.mol
Pimonidazole Property
- Melting point:
- 110-113°C
- Boiling point:
- 490.5±55.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >20mg/mL
- pka
- 14.06±0.20(Predicted)
- form
- powder
- color
- yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- N1165
- Product name
- Pimonidazole
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $168
- Updated
- 2024/03/01
- Product number
- N1165
- Product name
- Pimonidazole
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $405
- Updated
- 2024/03/01
- Product number
- 89130
- Product name
- Pimonidazole
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 89130
- Product name
- Pimonidazole
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $61
- Updated
- 2024/03/01
- Product number
- 89130
- Product name
- Pimonidazole
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $243
- Updated
- 2024/03/01
Pimonidazole Chemical Properties,Usage,Production
Description
Hypoxic cells are low oxygen cells that when present in tumors are radioresistant and chemoresistant. Pimonidazole is a small molecule radiosensitizer that has proven to be an effective and nontoxic hypoxia marker for human squamous cell carcinomas of the cervix, head, and neck. This immunochemical hypoxia marker has been widely used in experimental and clinical studies due to its chemical stability, water solubility, and wide tissue distribution. It is generally administered in aqueous solution by injection.
Uses
Pimonidazole is an effective and nontoxic hypoxia detection reagent. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids. It labels hypoxic tumor cells in vivo. Also labels hypoxic mesenchymal stem cells in mouse bone marrow.
Biochem/physiol Actions
Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids.
storage
Store at -20°C
Pimonidazole Preparation Products And Raw materials
Raw materials
Preparation Products
Pimonidazole Suppliers
View Lastest Price from Pimonidazole manufacturers
- Product
- Pimonidazole 70132-50-2
- Price
- US $350.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 9000kg/per week
- Release date
- 2021-09-10
- Product
- Pimonidazole 70132-50-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 0.999
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-13