(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid

Product Name: (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid
CAS No.: 68538-85-2
Chemical Name: (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid
Synonyms: (6S)-5-Formyltetrahydrofolic acid;(S)-Leucovorin;(6S)-Leucovorin;Folinic Acid EP Impurity H;Impurity H of Calcium Levofolinate;Folinic Acid Impurity H (Levofolinic Acid);N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid;L-Glutamic acid, N-[4-[[[(6S)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-;(-)-N-[4-[[[(6S)-2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxopteridin-6β-yl]methyl]amino]benzoyl]-L-glutamic acid;(S)-2-(4-((((S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
CBNumber: CB61253829
Molecular Formula: C20H23N7O7
Formula Weight: 473.44
MOL File: 68538-85-2.mol

More

Less

(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid Property

Density: 1.68±0.1 g/cm3(Predicted)
pka: 3.51±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid Chemical Properties,Usage,Production

Uses

Levoleucovorin (Levofolinic acid) is the pharmacologically active levoisomer of racemic leucovorin. Levoleucovorin can be used as a rescue agent after high-dose Methotrexate.html" class="link-product" target="_blank">Methotrexate (HY-14519) therapy, and in combination with fluorouracil for the research of advanced metastatic colorectal cancer[1].

Definition

ChEBI: The pharmacologically active (6S)-stereoisomer of 5-formyltetrahydrofolic acid.

References

[1] Chuang VT, et al. Levoleucovorin as replacement for leucovorin in cancer treatment. Ann Pharmacother. 2012 Oct;46(10):1349-57. DOI:10.1345/aph.1Q677

(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid Suppliers

China 25 India 1 United States 3 Global 29

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10109
Advantage: 58

Nanjing Daqin Pharmaceutical Technology Co., Ltd.

Tel: 025-025-58470199 18351831988
Fax: 025-58470199
Email: sales@daqinpharma.cn
Country: China
ProdList: 312
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
ProdList: 14246
Advantage: 58

Shenzhen ruikai de biotechnology co., ltd.

Tel: 0755-61348847 17820674378
Fax: 0755-21016893
Email: 2682116078@qq.com
Country: China
ProdList: 7843
Advantage: 58

Nanjing zehe Pharmaceutical Technology Co., Ltd

Tel: 17768115366
Email: henry124604479@163.com
Country: China
ProdList: 230
Advantage: 58

Changzhou Xianglong Pharmaceutical Technology Co., LTD

Tel: 18661161657
Email: yaoxiangqiu2021@163.com
Country: China
ProdList: 9968
Advantage: 58

Nanjing webright Pharmaceutical Technology Co., Ltd

Tel: 18066048793; 18014498793
Email: 1504914633@qq.com
Country: China
ProdList: 1318
Advantage: 58

Cato Research Chemicals Inc.

Tel: 020-81960175-877 18933936954
Email: tianwen.zhan@cato-chem.com
Country: China
ProdList: 7259
Advantage: 58

Shanghai Zerui Biotechnology Co., Ltd.

Tel: 021-54580889 18321124657
Fax: 021-54580889
Email: 731997554@qq.com
Country: China
ProdList: 10608
Advantage: 58

Guangzhou Zhenlin Pharmaceutical Technology Co., Ltd

Tel: 020-18102736 18102736234
Email: LK@zlstandards.com
Country: China
ProdList: 8206
Advantage: 58

Shaanxi Henghan New Materials Co., Ltd

Tel: 15719109892
Email: 907967238@qq.com
Country: China
ProdList: 2579
Advantage: 58

Hubei Moco Chemical Co., Ltd.

Tel: 18627753421; 18627756402
Fax: QQ：3001051413
Email: 3001051413@qq.com
Country: China
ProdList: 20319
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

TLC Pharmaceutical Standards Ltd.

Tel: 18012923235; 18012923235
Email: chinasales04@tlcstandards.com.cn
Country: China
ProdList: 7975
Advantage: 58

Hubei YoungXin Pharmaceutical Tech Co.,Ltd.

Tel: 0714-3999001 18696290611
Email: 3003339751@qq.com
Country: China
ProdList: 9487
Advantage: 58

Zibo Hangyu Biotechnology Development Co., Ltd

Tel: +86-0533-2185556 +8615965530500
Email: nickzhang@hangyubiotech.com
Country: China
ProdList: 8510
Advantage: 58

Chongqing jooe co., ltd

Tel: +undefined86-15223382610
Email: info@jooe.com
Country: China
ProdList: 6208
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Chemtour Biotech Co., Ltd

Tel: +8617327281506
Email: market@chemtour.com
Country: China
ProdList: 1521
Advantage: 58

NANJING HEALTHNICE PHARMACEUTICAL CO.,LTD

Tel: 025-83204593
Email: hnzyxz@healthnice.net
Country: CHINA
ProdList: 7
Advantage: 58

Shanghai Huilun (Jiangsu) Pharmaceutical Co., Ltd.

Tel: 0523-86201751
Email: peng_wenjun@hllife.com
Country: CHINA
ProdList: 7
Advantage: 58

Shanghai Huilun Jiangsu Pharmaceutical Co., Ltd.

Tel: --
Fax: --
Email: ma_xiaojun@hllife.com.cn
Country: China
ProdList: 3
Advantage: 58

68538-85-2, (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acidRelated Search:

4a-Hydroxy-5-methyltetrahydrofolic acid PTEROIC ACID 2-AMINO-4-HYDROXY-PTERIDINE-6-CARBALDEHYDE N-[4-[[(2-AMino-6,7,8,9-tetrahydro-8-Methyl-4,9-dioxo-4H-pyrazino[1,2-a]-1,3,5-triazin-7-yl)Methyl]aMino]benzoyl]-L-glutaMic Acid 2-Amino-7-(hydroxymethyl)-4(3H)-pteridinone 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE folcysteine Folic acid DIHYDROFOLIC ACID 5-Methyl Tetrahedropteroic Acid (Mixture of DiastereoMers) Folic Acid Impurity C 6-hydroxymethylpterin (S)-N-[4-[[(2-AMino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid 2,4,5-Triamino-6-hydroxypyrimidine sulfate 2-Amino-7-(chloromethyl)pteridin-4(1H)-one 10-Formylfolic Acid Calcium Levofolinate EP Impurity E Calcium levofolinate

(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid

(-)-N-[4-[[[(6S)-2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxopteridin-6β-yl]methyl]amino]benzoyl]-L-glutamic acid

(6S)-5-Formyltetrahydrofolic acid

(6S)-Leucovorin

(S)-Leucovorin

N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid

Folinic Acid EP Impurity H

Folinic Acid Impurity H (Levofolinic Acid)

Impurity H of Calcium Levofolinate

L-Glutamic acid, N-[4-[[[(6S)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-

(S)-2-(4-((((S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid

68538-85-2