Albuterol sulfate

ChemicalBook > CAS DataBase List > Albuterol sulfate

Product Name: Albuterol sulfate
CAS No.: 51022-70-9
Chemical Name: Albuterol sulfate
Synonyms: SALBUTAMOL SULFATE;SALBUTAMOL SULPHATE;ALBUTEROL SULPHATE;Mozal;Volma;Cetsim;Respax;Loftan;Asmalin;Asmadil
CBNumber: CB6129525
Molecular Formula: C13H23NO7S
Formula Weight: 337.39
MOL File: 51022-70-9.mol

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Albuterol sulfate Property

Melting point:: 180 °C
Flash point:: 250 °C
storage temp.: 2-8°C
solubility: 1 M NaOH: soluble50 mg/ml, clear to slightly hazy, yellow-green
color: White
Water Solubility: Soluble in water and 1M sodium hydroxide (50 mg/ml).
Merck: 216
BCS Class: 1
InChI: InChI=1S/C13H21NO3.H2O4S/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)
InChIKey: OVICLFZZVQVVFT-UHFFFAOYSA-N
SMILES: CC(C)(NCC(O)C1C=CC(O)=C(CO)C=1)C.S(O)(O)(=O)=O
CAS DataBase Reference: 51022-70-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 43-22
Safety Statements: 36/37-36
RIDADR: 2811
WGK Germany: 3
RTECS: ZE4400000
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR1053
Product name: Albuterol sulfate
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 1g
Price: $97.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP302
Product name: Salbutamol sulfate
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 100MG
Price: $255
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1012633
Product name: Albuterol sulfate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $436
Updated: 2024/03/01

Alfa Aesar

Product number: A18544
Product name: Salbutamol sulfate, 99%
Packaging: 1g
Price: $46.65
Updated: 2024/03/01

Alfa Aesar

Product number: A18544
Product name: Salbutamol sulfate, 99%
Packaging: 5g
Price: $195
Updated: 2024/03/01

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Albuterol sulfate Chemical Properties,Usage,Production

Description

Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood.

Chemical Properties

Albuterol sulfate is a white or practically white powder, freely soluble in water and slightly soluble in ethanol.

Uses

Albuterol Sulfate belongs to a class of bronchodilator drugs called β2-adrenoceptor agonists. It is a prescription medicine used to treat symptoms of bronchospasm. Albuterol Sulfate may be used alone or with other medications.

Definition

ChEBI: Albuterol sulfate is an ethanolamine sulfate salt. It is functionally related to an albuterol.

brand name

Accuneb (Dey); Proair (IVAX); Proventil (Schering); Ventolin (GlaxoSmithKline); Volmax (Muro); Vospire (Odyssey).

General Description

Albuterol belongs to the class of medicines known as bronchodilators. It is also called a short-acting beta-agonist (SABA).

Biological Activity

Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors.

Veterinary Drugs and Treatments

Albuterol is used principally in dogs and cats for its effects on bronchial smooth muscle to alleviate bronchospasm or cough. It is also used in horses as a bronchodilator.

storage

Store at RT

Mode of action

Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

References

https://en.wikipedia.org/wiki/Salbutamol
https://www.drugbank.ca/drugs/DB01001
http://www.rxlist.com/albuterol-sulfate-drug/indications-dosage.htm

Albuterol sulfate Preparation Products And Raw materials

Raw materials

Palladium chloride

Preparation Products

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View Lastest Price from Albuterol sulfate manufacturers

Dorne Chemical Technology co. LTD

Product: Albuterol sulfate 51022-70-9
Price: US $10.00/ASSAYS
Min. Order: 1ASSAYS
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-03-26

Shaanxi Dideu Medichem Co. Ltd

Product: Albuterol sulfate 51022-70-9
Price: US $0.01-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50 tons
Release date: 2020-04-24

Zibo Hangyu Biotechnology Development Co., Ltd

Product: 1-benzyl-4-hydroxy-2-methyl-1H-benzo[d]imidazole-6-carboxylic acid 1640981-19-6
Price: US $95.00-950.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2024-03-15

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