ChemicalBook > CAS DataBase List > Albuterol sulfate

Albuterol sulfate

Product Name
Albuterol sulfate
CAS No.
51022-70-9
Chemical Name
Albuterol sulfate
Synonyms
SALBUTAMOL SULFATE;SALBUTAMOL SULPHATE;ALBUTEROL SULPHATE;Mozal;Volma;Cetsim;Respax;Loftan;Asmalin;Asmadil
CBNumber
CB6129525
Molecular Formula
C13H23NO7S
Formula Weight
337.39
MOL File
51022-70-9.mol
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Albuterol sulfate Property

Melting point:
180 °C
Flash point:
250 °C
storage temp. 
2-8°C
solubility 
1 M NaOH: soluble50 mg/ml, clear to slightly hazy, yellow-green
form 
Solid
color 
White
Water Solubility 
Soluble in water and 1M sodium hydroxide (50 mg/ml).
Merck 
216
BCS Class
1
InChI
InChI=1S/C13H21NO3.H2O4S/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;1-5(2,3)4/h4-6,12,14-17H,7-8H2,1-3H3;(H2,1,2,3,4)
InChIKey
OVICLFZZVQVVFT-UHFFFAOYSA-N
SMILES
CC(C)(NCC(O)C1C=CC(O)=C(CO)C=1)C.S(O)(O)(=O)=O
CAS DataBase Reference
51022-70-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
43-22
Safety Statements 
36/37-36
RIDADR 
2811
WGK Germany 
3
RTECS 
ZE4400000
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1053
Product name
Albuterol sulfate
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$97.5
Updated
2024/03/01
Sigma-Aldrich
Product number
BP302
Product name
Salbutamol sulfate
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$255
Updated
2024/03/01
Sigma-Aldrich
Product number
1012633
Product name
Albuterol sulfate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Alfa Aesar
Product number
A18544
Product name
Salbutamol sulfate, 99%
Packaging
1g
Price
$46.65
Updated
2024/03/01
Alfa Aesar
Product number
A18544
Product name
Salbutamol sulfate, 99%
Packaging
5g
Price
$195
Updated
2024/03/01
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Albuterol sulfate Chemical Properties,Usage,Production

Description

Albuterol sulfate (Brand name: PROVENTIL® HFA) is the sulfate form of albuterol which is also known as salbutamol. It is a kind of short-acting, selective beta2-adrenergic receptor agonist being capable of opening up the medium and large airways in the lungs. It is mainly used for the treatment of bronchospasm (induced by bronchial asthma or exercise) as well as chronic obstructive pulmonary disease (COPD). Albuterol sulfate takes effects through directly biding to the beta (2)-adrenergic receptors in the lung and causing relaxation of bronchial smooth muscles. This relaxation is mediated by its effect of stimulating cAMP production through activating adenylate cyclase, further inhibiting the phosphorylation of myosin and lowering the intracellular calcium level. Albuterol sulfate can also be used to treat acute hyperkalemia of the blood.

Chemical Properties

Albuterol sulfate is a white or practically white powder, freely soluble in water and slightly soluble in ethanol.

Uses

Albuterol Sulfate belongs to a class of bronchodilator drugs called β2-adrenoceptor agonists. It is a prescription medicine used to treat symptoms of bronchospasm. Albuterol Sulfate may be used alone or with other medications.

Definition

ChEBI: Albuterol sulfate is an ethanolamine sulfate salt. It is functionally related to an albuterol.

brand name

Accuneb (Dey); Proair (IVAX); Proventil (Schering); Ventolin (GlaxoSmithKline); Volmax (Muro); Vospire (Odyssey).

General Description

Albuterol belongs to the class of medicines known as bronchodilators. It is also called a short-acting beta-agonist (SABA).

Biological Activity

Non-selective β -adrenergic agonist, more potent at β 2 than β 1 receptors.

Veterinary Drugs and Treatments

Albuterol is used principally in dogs and cats for its effects on bronchial smooth muscle to alleviate bronchospasm or cough. It is also used in horses as a bronchodilator.

storage

Store at RT

Mode of action

Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.

References

https://en.wikipedia.org/wiki/Salbutamol
https://www.drugbank.ca/drugs/DB01001
http://www.rxlist.com/albuterol-sulfate-drug/indications-dosage.htm

Albuterol sulfate Preparation Products And Raw materials

Raw materials

Palladium chloride

Preparation Products

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Albuterol sulfate Suppliers

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View Lastest Price from Albuterol sulfate manufacturers

Dorne Chemical Technology co. LTD
Product
Albuterol sulfate 51022-70-9
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
10 ton
Release date
2024-03-26
Baoji Guokang Bio-Technology Co., Ltd.
Product
Albuterol sulfate 51022-70-9
Price
US $2380.00/KG
Min. Order
1Kg/Bag
Purity
98%
Supply Ability
1000KG
Release date
2021-06-04
Hebei Yanxi Chemical Co., Ltd.
Product
Albuterol sulfate 51022-70-9
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-09-26

51022-70-9, Albuterol sulfateRelated Search:

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