ADRENORPHIN

Product Name: ADRENORPHIN
CAS No.: 88866-92-6
Chemical Name: ADRENORPHIN
Synonyms: Metorphacid;ADRENORPHIN;METORPHAMIDE;METORPHINAMIDE;ADRENORPHIN (FREE ACID);METORPHAMIDE (FREE ACID);Adrenorphin, ≥95% (HPLC);Tyr-Gly-Gly-Phe-Arg-Arg-Val;8-L-Valineadrenorphin (human);TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL
CBNumber: CB6129590
Molecular Formula: C44H68N14O10S
Formula Weight: 985.16
MOL File: 88866-92-6.mol

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ADRENORPHIN Property

Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: ≥27.75 mg/mL in H2O with ultrasonic; ≥5.64 mg/mL in EtOH with ultrasonic; ≥98.5 mg/mL in DMSO
form: solid
pka: 3.34±0.10(Predicted)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T8156
Product name: Adrenorphin
Purity: ≥95% (HPLC)
Packaging: 1mg
Price: $163
Updated: 2022/05/15

Alfa Aesar

Product number: J66389
Product name: Adrenorphin, free acid
Packaging: 5mg
Price: $169
Updated: 2021/12/16

Usbiological

Product number: A0909-41
Product name: Adrenorphin
Packaging: 1mg
Price: $531
Updated: 2021/12/16

Usbiological

Product number: A0909-41A
Product name: Adrenorphin, free acid
Packaging: 1mg
Price: $531
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb364179
Product name: Adrenorphin (Free acid)
Purity: > 95%
Packaging: 5mg
Price: $552.5
Updated: 2021/12/16

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ADRENORPHIN Chemical Properties,Usage,Production

Uses

Metorphacid Trifluoroacetate Salt is amino acid sequence; protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components.

Biological Activity

adrenorphin, also sometimes referred to as metorphamide, is an endogenous, c-terminally amidated, opioid octapeptide that is produced from proteolytic cleavage of proenkephalin a and is widely distributed throughout the mammalian brain(1). it was named based on the fact that it was originally detected in human phaeochromocytoma tumour derived from the adrenal medulla, and was subsequently found in normal human and bovine adrenal medulla as well. adrenorphin exhibits potent opioid activity, acting as a balanced μ- and κ-opioid receptor agonist while having no effects on δ-opioid receptors(2). it possesses analgesic and respiratory deppresive properties(3).figure 1 proteolytic cleavage of proenkephalin a

References

1. Matsuo H, Miyata A, Mizuno K (1983). "Novel C-terminally amidated opioid peptide in human phaeochromocytoma tumour". Nature 305 (5936): 721–3.2. Weber E, Esch FS, Böhlen P et al. (December 1983). "Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain". Proceedings of the National Academy of Sciences of the United States of America 80 (23): 7362–6.3. Xu SF, Lu WX, Zhou KR et al. (April 1985). "The analgesic and respiratory depressant actions of metorphamide in mice and rabbits". Neuropeptides 6 (2): 121–31.

ADRENORPHIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ADRENORPHIN Suppliers

China 58 Switzerland 1 United States 12 Global 71

Alabiochem Tech.Co., Ltd.

Tel: 0512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 995
Advantage: 59

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

ApexBio Technology LLC

Tel: +1-832-696-8203
Fax: +1-832-641-3177
Email: info@apexbt.com
Country: United States
ProdList: 477
Advantage: 60

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Watson Biotechnology Co.,Ltd

Tel: 027-027-59207879 18140587686
Fax: QQ：1972026995
Email: kf@3600chem.com
Country: China
ProdList: 4699
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9947
Advantage: 58

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 18502815961
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14623
Advantage: 60

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View Lastest Price from ADRENORPHIN manufacturers

Career Henan Chemical Co

Product: ADRENORPHIN 88866-92-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

Career Henan Chemical Co

Product: ADRENORPHIN 88866-92-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

88866-92-6, ADRENORPHINRelated Search:

(MET(O)5)-ENKEPHALIN [LEU5]-ENKEPHALIN MET-ENKEPHALIN-ARG-PHE H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-OH MERGL LEU-ENKEPHALIN-ARG MET-ENKEPHALIN-ARG-ARG H-TYR-LYS-GLY-ARG-CYCLO(-GLU-TYR-ILE-LYS)-LEU-ILE-THR-ARG-PRO-ARG-TYR-NH2 ADRENORPHIN DES-TYR1-METHIONINE ENKEPHALINAMIDE ACETATE SALT H-ARG-VAL-OH ACETATE SALT METHIONINE ENKEPHALINAMIDE ACETATE SALT ADRENORPHIN Met-enkephalinamide Glycyl-glycyl-L-valine

METORPHAMIDE (FREE ACID)

METORPHINAMIDE

METORPHAMIDE

H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-OH

ADRENORPHIN (FREE ACID)

ADRENORPHIN

TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL

Adrenorphin, ≥95% (HPLC)

8-L-Valineadrenorphin (human)

Metorphacid

Tyr-Gly-Gly-Phe-Arg-Arg-Val

Metorphamide (free acid) H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-OH

L-Valine, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-

88866-92-6

C44H68N14O10S

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

Peptides

Other Peptides

Neuroscience