PSEUDOJERVINE
- Product Name
- PSEUDOJERVINE
- CAS No.
- 36069-05-3
- Chemical Name
- PSEUDOJERVINE
- Synonyms
- PSEUDOJERVINE;Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-11(1H)-one, 3-(β-D-glucopyranosyloxy)-2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11a,11b-hexadecahydro-3',6',10,11b-tetramethyl-, (2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-
- CBNumber
- CB61424850
- Molecular Formula
- C33H49NO8
- Formula Weight
- 587.749
- MOL File
- 36069-05-3.mol
PSEUDOJERVINE Property
- Melting point:
- 300-301° (dec)
- alpha
- D25 -133° (c = 0.48 in 1:3 ethanol-chloroform)
- Boiling point:
- 643.44°C (rough estimate)
- Density
- 1.1485 (rough estimate)
- refractive index
- 1.5960 (estimate)
- pka
- 12.91±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- PXT0001972
- Product name
- PSEUDOJERVINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.44
- Updated
- 2021/12/16
PSEUDOJERVINE Chemical Properties,Usage,Production
Description
This alkaloid has been found in both Veratrum album and V. viride Ait. It crystallizes from EtOH in hexagonal tablets and has [α]20D - 139° (CHC13). The hydrochloride dihydrate has m.p. 254-6°C (dry, dec.); the sulphate is also crystalline but the aurichloride is amorphous. Poethke has shown that the alkaloid is a secondary base, gives a nitro so derivative, m.p. 261°C, and contains five replaceable hydrogen atoms. On boiling with dilute HCl it is hydrolyzed to (+)- glucose and isojervine, an isomer of jervine. This latter base crystallizes with solvent, e.g. the CHC13 adduct softens at 135-1500 C; the crystallizate with EtOH has m.p. 114-6°C (dec.) and that with Me2CO has m.p. 110-4°C; [α]20D - 32° (EtOH).
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Veratrum nigrum L.
Uses
Pseudojervine is a glycoalkaloid with a feeble inhibition activity against platelet aggregation[1].
Definition
ChEBI: Pseudojervine is a steroid saponin.
References
Wright, Luff., J. Chem. Soc., 35,405,421 (1879)
Salzberger., Arch. Pharm., 228,462 (1890)
Poethke., ibid, 275,357,571 (1937)
Poethke., ibid, 276, 170 (1938)
Jacobs, Craig.,J. Biol. Chem., 155,564 (1944)
PSEUDOJERVINE Preparation Products And Raw materials
Raw materials
Preparation Products
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