ChemicalBook > CAS DataBase List > 2-Chloro-4-methylbenzaldehyde

2-Chloro-4-methylbenzaldehyde

Product Name
2-Chloro-4-methylbenzaldehyde
CAS No.
50817-80-6
Chemical Name
2-Chloro-4-methylbenzaldehyde
Synonyms
2-Chloro-p-tolualdehyde;2-CHLORO-4-METHYLBENZALDEHYDE;Benzaldehyde,2-chloro-4-methyl-;2-Chloro-4-methylbenzaldehyde 97%;3-Chloro-4-formyltoluene, 2-Chloro-p-tolualdehyde;2-CHLORO-4-METHYLBENZALDEHYDE2-CHLORO-4-METHYLBENZALDEHYDE
CBNumber
CB61476389
Molecular Formula
C8H7ClO
Formula Weight
154.59
MOL File
50817-80-6.mol
More
Less

2-Chloro-4-methylbenzaldehyde Property

Melting point:
27-30°C
Boiling point:
100-103 °C(Press: 4 Torr)
Density 
1.195±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
Appearance
Light yellow to yellow <27°C Solid,>30°C Liquid
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41-51
Safety Statements 
26-39-45
WGK Germany 
3
HS Code 
2913000090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
776963
Product name
2-Chloro-4-methylbenzaldehyde
Purity
97%
Packaging
1g
Price
$57.3
Updated
2023/06/20
TRC
Product number
C602098
Product name
2-Chloro-4-methylbenzaldehyde
Packaging
100mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
2715-5-X1
Product name
2-Chloro-4-methylbenzaldehyde
Packaging
1g
Price
$40
Updated
2021/12/16
AK Scientific
Product number
W6599
Product name
2-Chloro-4-methylbenzaldehyde
Packaging
1g
Price
$70
Updated
2021/12/16
Matrix Scientific
Product number
076547
Product name
2-Chloro-4-methylbenzaldehyde
Purity
95+%
Packaging
5g
Price
$78
Updated
2021/12/16
More
Less

2-Chloro-4-methylbenzaldehyde Chemical Properties,Usage,Production

Synthesis

6627-51-6

68-12-2

50817-80-6

GENERAL STEPS: 165 mL (413 mmol) of a hexane solution of 2.5 M n-butyllithium (nBuLi) was slowly added dropwise to 82.2 g (400 mmol) of 4-bromo-3-chlorotoluene dissolved in 400 mL of tetrahydrofuran (THF) over a period of 1 h. The reaction system was required to be cooled to -88 °C. At this temperature, the reaction mixture was stirred continuously for 30 min. Subsequently, 44.0 g (602 mmol) of N,N-dimethylformamide (DMF) was added dropwise over 10 minutes by vigorous stirring. The reaction mixture was stirred overnight at room temperature. After that, 100 mL of water and 400 mL of 3 N hydrochloric acid (HCl) were added to the reaction mixture at 0 °C. The organic layer was separated and the aqueous layer was extracted with dichloromethane (2 x 125 mL). The organic extracts were combined, dried with potassium carbonate (K2CO3), and filtered through a short silica gel 60 (40-63 μm) layer. The silica gel layer was washed with 50 mL of dichloromethane. The organic eluates were combined and evaporated to dryness to give a light orange liquid. The liquid was distilled under vacuum and the fractions with boiling points of 99-102 °C/11 mmHg were collected to give 58.0 g (94% yield) of 2-chloro-4-methylbenzaldehyde as a colorless liquid, which crystallized after standing overnight.

References

[1] Patent: WO2014/96282, 2014, A1. Location in patent: Page/Page column 35
[2] Patent: WO2018/91684, 2018, A1. Location in patent: Page/Page column 73; 74

2-Chloro-4-methylbenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Chloro-4-methylbenzaldehyde Suppliers

China 97 India 3 Slovakia 1 Switzerland 1 United Kingdom 4 United States 10 Global 116
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Accela ChemBio Inc.
Tel
+1(858) 699-3322
Fax
+1(858) 876-1948
Email
marketing@accelachem.com
Country
United States
ProdList
6024
Advantage
65
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
More
Less

View Lastest Price from 2-Chloro-4-methylbenzaldehyde manufacturers

Career Henan Chemical Co
Product
2-Chloro-4-methylbenzaldehyde 50817-80-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10

50817-80-6, 2-Chloro-4-methylbenzaldehydeRelated Search:

CHLOROMETHYLPHENYLSILANE p-Tolualdehyde Chloromethyltrimethylsilane 3-(Trifluoromethyl)benzaldehyde 2-Chloro-5-chloromethylpyridine 2-(Trifluoromethyl)benzaldehyde tert-Butyldimethylsilyl chloride 2-CHLORO-4-METHOXYPHENOL 2-CHLORO-4-METHOXYBENZONITRILE Difluorochloromethane Chloromethyl methyl ether 2,5-DICHLOROTEREPHTHALIC ACID 2,6-DICHLORO-4-(TRIFLUOROMETHYL)BENZAMIDE Dacthal Chlorthal Dimethyl chloroterephthalate TETRACHLORO-4-TRIFLUOROMETHYLBENZOYLFLUORIDE 2-BROMO-2',6'-DICHLORO-4'-(TRIFLUOROMETHYL)-ACETOPHENONE

  • 2-CHLORO-4-METHYLBENZALDEHYDE
  • 3-Chloro-4-formyltoluene, 2-Chloro-p-tolualdehyde
  • 2-Chloro-p-tolualdehyde
  • Benzaldehyde,2-chloro-4-methyl-
  • 2-CHLORO-4-METHYLBENZALDEHYDE2-CHLORO-4-METHYLBENZALDEHYDE
  • 2-Chloro-4-methylbenzaldehyde 97%
  • 50817-80-6
  • Aldehydes
  • Phenyls & Phenyl-Het