2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE

ChemicalBook > CAS DataBase List > 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE

Product Name: 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
CAS No.: 36341-25-0
Chemical Name: 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
Synonyms: Y109;Y-109;YL-109;Y-109;Y109;Phenol, 4-(2-benzothiazolyl)-2-methoxy-;4-(benzo[d]thiazol-2-yl)-2-Methoxyphenol;4-(1,3-Benzothiazol-2-yl)-2-methoxyphenol;2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE;4-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,5-dien-1-one;inhibit,aryl,YL 109,hydrocarbon,AhR,antitumor,Aryl Hydrocarbon Receptor,YL109,carboxyl,breast,Hsp70-interacting,CHIP,protein,AhR,cancer,YL-109,terminus,invasiveness,Inhibitor
CBNumber: CB61477104
Molecular Formula: C14H11NO2S
Formula Weight: 257.31
MOL File: 36341-25-0.mol

Less

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Property

storage temp.: 2-8°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 1 mg/ml
form: A crystalline solid
color: Light yellow to yellow

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 30290
Product name: YL-109
Packaging: 5mg
Price: $110
Updated: 2024/03/01

Cayman Chemical

Product number: 30290
Product name: YL-109
Packaging: 50mg
Price: $380
Updated: 2024/03/01

Cayman Chemical

Product number: 30290
Product name: YL-109
Packaging: 10mg
Price: $195
Updated: 2024/03/01

Cayman Chemical

Product number: 30290
Product name: YL-109
Packaging: 25mg
Price: $352
Updated: 2024/03/01

AK Scientific

Product number: 3261AH
Product name: 4-(Benzo[D]thiazol-2-yl)-2-methoxyphenol
Packaging: 1g
Price: $520
Updated: 2021/12/16

Less

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Chemical Properties,Usage,Production

Biological Activity

YL-109 is a novel antitumor agent that inhibits the growth and invasion of breast cancer cells in vitro and in vivo.

in vitro

YL-109 (0.001-10 μM; 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells.
YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells.

Cell Proliferation Assay

< td class="col2"> MCF-7 and MDA-MB-231 cells

Cell Line:
Concentration:	0.001, 0.01, 0.1, 1, 10 μM
Incubation Time:	96 hours
Result:	Strongly inhibited cell proliferation of MCF-7 and MDA-MB-231 cells in a dose-dependent manner (IC ₅₀ =85.8 nM and 4.02 μM, respectively).

in vivo

YL-109 (15 mg/kg; sc for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo.

< /p>

Animal Model:	BALB/cAjcl-nu/nu female mice (4-5 weeks) inoculated with MCF-7 or MDA-MB-231 cells
Dosage:	15 mg/kg
Administration: < /td>	Sc every 2 days for 63 days
Result:	Suppressed tumor growth in mice injected with MCF-7 and MDA-MB-231 cells.

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Suppliers

China 47 India 1 United States 11 Global 59

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Guangzhou Zhiya Chemdrugs Co.,Ltd

Tel: 18122150900
Fax: QQ:2869377561
Email: sculk28@163.com
Country: China
ProdList: 646
Advantage: 55

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 4966
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7296
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1925
Advantage: 55

Zhengzhou Huiju Chemical Co., Ltd.

Tel: 0371-55900031 18137872243
Fax: QQ：2853979815
Email: 2853979815@qq.com
Country: China
ProdList: 10001
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28806
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9353
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 14377
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3253
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52693
Advantage: 58

Shanghai Maruhua Science and Technology Co. Ltd.

Tel: 021-57171708; 18721745940
Fax: QQ1139783351
Email: sales2@api-chem.com
Country: China
ProdList: 1884
Advantage: 58

Aishilun biotechnology (Shanghai) co., LTD

Tel: 021-50676523 18019098996
Email: info@acelybio.com
Country: China
ProdList: 3960
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30239
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

Changzhou Chenhong Biotechnology Co., Ltd.

Tel: 0519-85788828 13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 3600
Advantage: 58

Shanghai Zeye Biotechnology Co., Ltd.

Tel: 021-61998551 13122364865
Email: sale1@shzysw.net
Country: China
ProdList: 9772
Advantage: 58

Beijing Haite lesk Technology Co., Ltd

Tel: 15210893940; 15116916250
Fax: QQ: 237008221
Email: chemistryliu@163.com
Country: China
ProdList: 7327
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: wulan@absin.cn
Country: China
ProdList: 24731
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

cjbscvictory

Tel: 13348960310 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10011
Advantage: 58

Abmole Bioscience Inc.

Tel: 021-50967598 02150967598
Email: sales@abmole.cn
Country: China
ProdList: 4494
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 7999
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7890
Advantage: 58

ChemeGen 中国

Tel: 18818260767
Fax: QQ 3610331285
Email: 2625930290@qq.com
Country: China
ProdList: 6973
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 62075
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

Heze Aiding Pharmaceutical Co., Ltd

Tel: 17661365138
Email: 2845578351@qq.com
Country: China
ProdList: 7107
Advantage: 58

Jining Yize Pharmaceutical Technology Co., Ltd

Tel: 15192473210 15192473210
Email: 302633902@qq.com
Country: China
ProdList: 4480
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12005
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48461
Advantage: 58

BEIJINGYIWANJINGRUI

Tel: 15866847540
Email: dengyt2000@163.com
Country: China
ProdList: 4100
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9266
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 17691182729 13992773979
Email: 1049@dideu.com
Country: China
ProdList: 8012
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 32957
Advantage: 60

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Shanghai Qiming Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6502
Advantage: 58

36341-25-0, 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLERelated Search:

YKL-5-124 yk11 YK-4-279 YKL 06-061 YL 0919

2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE

YL-109

4-(benzo[d]thiazol-2-yl)-2-Methoxyphenol

Y109

Y-109

Y-109;Y109

4-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,5-dien-1-one

4-(1,3-Benzothiazol-2-yl)-2-methoxyphenol

Phenol, 4-(2-benzothiazolyl)-2-methoxy-

inhibit,aryl,YL 109,hydrocarbon,AhR,antitumor,Aryl Hydrocarbon Receptor,YL109,carboxyl,breast,Hsp70-interacting,CHIP,protein,AhR,cancer,YL-109,terminus,invasiveness,Inhibitor

36341-25-0

Inhibitors