ChemicalBook > CAS DataBase List > 4-Amino-2,6-dichloropyridine

4-Amino-2,6-dichloropyridine

Product Name: 4-Amino-2,6-dichloropyridine
CAS No.: 2587-02-2
Chemical Name: 4-Amino-2,6-dichloropyridine
Synonyms: 2,6-DICHLOROPYRIDIN-4-AMINE;2,6-DICHLORO-PYRIDIN-4-YLAMINE;2,6-dichloro-4-pyridinamine;2,6-DICHLORO-4-AMINOPYRIDINE;0/2/87;NSC 136573;AURORA KA-3022;4-Amino-2,6-dichL;6-Dichloro-4-pyridinamine;4-Ami-2,6-dichloropyridine
CBNumber: CB6151104
Molecular Formula: C5H4Cl2N2
Formula Weight: 163
MOL File: 2587-02-2.mol

Less

4-Amino-2,6-dichloropyridine Property

Melting point:: 169-173 °C (lit.)
Boiling point:: 336.7±37.0 °C(Predicted)
Density: 1.497±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Powder
pka: 0.49±0.50(Predicted)
color: White to buff
BRN: 114351
InChI: InChI=1S/C5H4Cl2N2/c6-4-1-3(8)2-5(7)9-4/h1-2H,(H2,8,9)
InChIKey: WAEZOSSWRXDWAX-UHFFFAOYSA-N
SMILES: C1(Cl)=NC(Cl)=CC(N)=C1
CAS DataBase Reference: 2587-02-2(CAS DataBase Reference)
NIST Chemistry Reference: Pyridine, 4-amino-2,6-dichloro-(2587-02-2)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333990

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 565342
Product name: 4-Amino-2,6-dichloropyridine
Purity: 97%
Packaging: 5g
Price: $65.4
Updated: 2025/07/31

TCI Chemical

Product number: A2369
Product name: 4-Amino-2,6-dichloropyridine
Purity: >97.0%(GC)(N)
Packaging: 1g
Price: $40
Updated: 2025/07/31

TCI Chemical

Product number: A2369
Product name: 4-Amino-2,6-dichloropyridine
Purity: >97.0%(GC)(N)
Packaging: 5g
Price: $122
Updated: 2025/07/31

TRC

Product number: A604710
Product name: 4-Amino-2,6-dichloropyridine
Packaging: 5g
Price: $60
Updated: 2021/12/16

TRC

Product number: A604710
Product name: 4-Amino-2,6-dichloropyridine
Packaging: 10g
Price: $95
Updated: 2021/12/16

Less

4-Amino-2,6-dichloropyridine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

4-Amino-2,6-dichloropyridine is a compound useful in organic synthesis used in the synthesis of Rho kinase inhibitors.

Synthesis

25194-01-8

2587-02-2

The general procedure for the synthesis of 4-amino-2,6-dichloropyridine from 2,6-dichloro-4-nitropyridine was as follows: to a solution of 2,6-dichloro-4-nitropyridine (14.82 g, 76.79 mmol) in ethanol (350 mL) was added sequentially iron powder (19.91 g, 356.58 mmol), water (65.8 mL, 3.6 mol), and concentrated hydrochloric acid (14.1 mL, 464.1 mmol). The reaction was carried out at 95 °C with stirring for 16 hours. After completion of the reaction, the reaction solution was cooled to room temperature and the pH was adjusted to neutral. After filtration, the filtrate was concentrated and extracted with ethyl acetate. The organic phases were combined, dried with anhydrous magnesium sulfate, and the solvent was removed by rotary evaporation to afford 11.9 g of the title product 4-amino-2,6-dichloropyridine in 95.1% yield.

References

[1] Patent: US2012/289497, 2012, A1. Location in patent: Page/Page column 51-52
[2] Patent: EP2524917, 2012, A1. Location in patent: Page/Page column 58-59
[3] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 3, p. 1511 - 1530
[4] Nucleosides, Nucleotides and Nucleic Acids, 2003, vol. 22, # 12, p. 2133 - 2144
[5] ChemCatChem, 2016, vol. 8, # 8, p. 1485 - 1489

4-Amino-2,6-dichloropyridine Preparation Products And Raw materials

Raw materials

2,6-Dichloropyridine Ethanol Acetone Hydrogen peroxide Sodium sulfate Potassium carbonate Trifluoroacetic acid Chloroform Phosphorus trichloride Diethyl ether Kieserite Ethyl acetate Hydrochloric acid Nitric acid Acetic acid Iron Sulfuric acid Sodium carbonate

Preparation Products

Less

4-Amino-2,6-dichloropyridine Suppliers

Americas 1 Austria 1 Belgium 1 Canada 2 China 281 Europe 3 Germany 3 India 21 Japan 1 Poland 1 Switzerland 2 The Netherlands 1 United Kingdom 15 United States 32 Global 365

LEWOO PHARMATECH (SHANGHAI) CO.,LTD

Tel: 15800805830
Fax: 021 67898603
Email: miao@lewoopharma.com.cn
Country: China
ProdList: 932
Advantage: 58

Wuxi Kehua Biological Technology Co., Ltd.

Tel: 0510-86838766 13636419861
Email: 2258830676@qq.com
Country: China
ProdList: 5044
Advantage: 58

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

Shanghai Taijilin Industrial Co., Ltd.

Tel: 021-50630626 18964684208
Fax: 021-50563898
Email: kate@tajilin.com
Country: China
ProdList: 1291
Advantage: 58

Record Tech (Shanghai) Co., LTD

Tel: 13761627472
Fax: 86-21-64965863
Email: 183009664@qq.com
Country: China
ProdList: 649
Advantage: 62

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 993
Advantage: 62

Fengcheng Meditech (Tianjin)Co., Ltd

Tel: 022-59002498-8008; 15122574756
Email: info@fcmeditech.com
Country: China
ProdList: 68
Advantage: 58

Deyang haijungang Technology Co., Ltd

Tel: 15883665058
Email: dyhjgkj@126.com
Country: China
ProdList: 554
Advantage: 58

SiChuang NanBu Honesty Technology Co., Ltd.

Tel: 0838-5675166 15883665058
Fax: 0838-5675535
Email: nbcxkj@126.com
Country: China
ProdList: 919
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9309
Advantage: 66

ZEROSCHEM.CO.,LTD.

Tel: 10-61256048 13810278579
Fax: +86 10 61256049
Email: sales@zeroschem.com
Country: China
ProdList: 1371
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

shanghai Rainbow MediTech.Co.Ltd.

Tel: 021-64968085,64968086-5815,5812; 13472757003
Fax: +86 21 64968087
Email: xiaoxia.zeng@rainbowpharma.cn
Country: China
ProdList: 961
Advantage: 65

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Wuhan Arike Technology Co., Ltd.

Tel: 027- 51832457 94518350
Fax: E-Mail Inquiry
Country: China
ProdList: 746
Advantage: 62

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Atop-Pharma (Shanghai) Technology Co., Ltd.

Tel: +86 (21) 5196-9732
Fax: +86 (21) 5196-9733
Country: China
ProdList: 996
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 3997
Advantage: 55

Tianjin Jinyuda Chemical Co., Ltd.

Tel: 022-58013646 13011382049
Fax: 022-23854368
Email: sales@jinyudachem.com
Country: China
ProdList: 1930
Advantage: 55

Shanghai Youd Chemical Technology Co., Ltd.

Tel: 021-37910092; 15821801668
Fax: 021-37910267
Email: cong44@126.com
Country: China
ProdList: 294
Advantage: 58

Chiba Pharmaceutical Science and technology Co, Ltd.

Tel: 0531-81313138 13066006660
Fax: QQ: 3366077777
Email: chibapharm@foxmail.com
Country: China
ProdList: 3991
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Ascepion Pharmaceuticals, Inc.

Tel: +86-512-86881668
Fax: +86-512-62956001
Country: China
ProdList: 100
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Shanghai Hao Yun Chemical Science Co.,Ltd.

Tel: 021-68367562 15002147577;
Fax: 021-68369562
Email: sales@haoyunchem.com
Country: China
ProdList: 457
Advantage: 55

Chimica Laboratories Co., Ltd

Tel: 0086-573-82585213
Fax: 0086-573-82585233
Email: bai@chimicalabs.com
Country: China
ProdList: 861
Advantage: 64

Shanghai Hong-chuang Pharma Tech Co., Ltd.

Tel: 18151128828
Fax: -
Email: hc-sales@foxmail.com
Country: China
ProdList: 2647
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Less

View Lastest Price from 4-Amino-2,6-dichloropyridine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 4-Amino-2,6-dichloropyridine 2587-02-2
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-19

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Amino-2,6-dichloropyridine 2587-02-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-01

R&D Scientific Inc.

Product: 2,6-Dichloropyridin-4-amine 2587-02-2
Price: US $2100.00/Kg
Min. Order: 1Kg
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-04-11

2587-02-2, 4-Amino-2,6-dichloropyridineRelated Search:

ALTRENOGEST Bis(2-ethylhexyl)amine 2,6-Diaminopyridine Clopyralid Aniline 2,6-Lutidine Betaine 2-Aminopyridine 2-Chloro-5-chloromethylpyridine Glycine 2,5-Dichloropyridine 3-Aminopyridine 4-Dimethylaminopyridine 4-Aminopyridine 2,3-Dichloropyridine 2,6-Dichloropyridine 2,6-DICHLORO-4-ISOCYANATOPYRIDINE 3-AMINO-2,6-DICHLOROPYRIDINE

2,6-Dichloropyridine-4-amine

4-Amino-2,6-dichloropyridine, 98+%

4-Amino-2,6-dichloropyridine ,97%

(4-AMino-2,6-dichloropyridine)4-AMino-2,6-dichloropyridine

NSC 136573

4- aMino-2,6- twochlorine pyridine

4-AMino-2,6-dichloropyridine 97%

4-AMino-2,6-dichloropyridine, 97.5%

2,6-DICHLORO-4-AMINOPYRIDINE

2,6-DICHLOROPYRIDIN-4-AMINE

2,6-DICHLORO-PYRIDIN-4-YLAMINE

4-Pyridinamine, 2,6-dichloro-

4-AMINO-2,6-DICHLOROPYRIDINE

AURORA KA-3022

2,6-dichloro-4-pyridinamine

4-Ami-2,6-dichloropyridine

4-Amino-2,6-dichloropyridine &gt

4-Amino-2,6-dichL

4-Amino-2,6-dichloropyridine ISO 9001：2015 REACH

4-amino-2,6-dichloropyridine-2587-02-2

6-Dichloro-4-pyridinamine

0/2/87

2,6-Dichloropyridine-4-amine 98%

2587-02-2

2587-2-2

2/2/2587

2687-02-2

2587-02-0

2587/2/2

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyridines

Building Blocks

C5 to C6

Chemical Synthesis

Nucleotides and Nucleosides

Bases & Related Reagents

Nucleotides

Amines

Aromatics

Heterocycles

Pyridine

Heterocycle-Pyridine series

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridines