4-Chlorobenzhydrol
- Product Name
- 4-Chlorobenzhydrol
- CAS No.
- 119-56-2
- Chemical Name
- 4-Chlorobenzhydrol
- Synonyms
- Chlorobenzhydrol;Cetirizine 4-Chlorobenzhydrol Impurity;AURORA KA-7061;4-CHLOROBENZHYDROL;Meclizine USP RC A;P-CHLORO BENZHYDROL;4-Chlorobenzohydrol;p-Chlorobenzohydrol;Benzhydrol, p-chloro-;Benzhydrol, 4-chloro-
- CBNumber
- CB6151432
- Molecular Formula
- C13H11ClO
- Formula Weight
- 218.68
- MOL File
- 119-56-2.mol
4-Chlorobenzhydrol Property
- Melting point:
- 58-60 °C (lit.)
- Boiling point:
- 150-151°C 2,6mm
- Density
- 1.1178 (rough estimate)
- refractive index
- 1.5260 (estimate)
- Flash point:
- 150-151°C/2.6mm
- storage temp.
- 2-8°C
- solubility
- insoluble
- pka
- 13.34±0.20(Predicted)
- color
- White to Off-White
- Water Solubility
- insoluble
- BRN
- 2050235
- CAS DataBase Reference
- 119-56-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenemethanol, 4-chloro-«alpha»-phenyl-(119-56-2)
- EPA Substance Registry System
- Benzenemethanol, 4-chloro-.alpha.-phenyl- (119-56-2)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 24/25-36-26
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 29062990
N-Bromosuccinimide Price
- Product number
- PHR3034
- Product name
- Meclizine Related Compound A
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 30MG
- Price
- $460
- Updated
- 2024/03/01
- Product number
- 1377010
- Product name
- Meclizine Related Compound A
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 15mg
- Price
- $1490
- Updated
- 2024/03/01
- Product number
- 124982
- Product name
- 4-Chlorobenzhydrol
- Purity
- 98%
- Packaging
- 1g
- Price
- $12.48
- Updated
- 2024/03/01
- Product number
- C0989
- Product name
- 4-Chlorobenzhydrol
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $36
- Updated
- 2024/03/01
- Product number
- C0989
- Product name
- 4-Chlorobenzhydrol
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $349
- Updated
- 2024/03/01
4-Chlorobenzhydrol Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
4-Chlorobenzhydrol was used as internal standard to measure the N-demethyl antipyrine metabolite in urine by gas chromatography-mass spectrometry. It was also used in the identification of the antihistamine cetirizine as a relevant cross-reactant for the carbamazepine-specific enzyme-linked immunosorbent assay .
Preparation
Preparation of 4-Chlorobenzhydrol(4-CB):
about 5.0g(0.023 mol) of 4-chloro benzophenone was dissolved in 15 mL of isopropyl alcohol (IPA) and heated to 50°C followed by the addition of 0.265g(0.007 mol) of sodium borohydride as a lot with the temperature maintained at 65°C for 2 h. The reaction mixture was distilled to expel isopropyl alcohol up to 90 %. The resulting solution was cooled and treated with dil HCl (5 mL of conc. HCl in 20 mL of water). Finally the reaction mass was extracted with 15 mL of toluene. The toluene extract was washed withwater to pH-7. The compound obtained in this step was taken to next step without isolation but aliquot sample was concentrated, isolated and checked for melting point (m.p. = 58-60°C).
Definition
ChEBI: P-Chlorobenzhydrol is a diarylmethane.
4-Chlorobenzhydrol Preparation Products And Raw materials
Raw materials
Preparation Products
4-Chlorobenzhydrol Suppliers
- Tel
- --
- Fax
- --
- sales21@chemicalland21.com
- Country
- South Korea
- ProdList
- 6303
- Advantage
- 74
View Lastest Price from 4-Chlorobenzhydrol manufacturers
- Product
- 4-Chlorobenzhydrol 119-56-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
- Product
- 4-Chlorobenzhydrol 119-56-2
- Price
- US $30.00-10.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-11-17
- Product
- 4-Chlorobenzhydrol 119-56-2
- Price
- US $99.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1 ton
- Release date
- 2021-12-21