Otenabant

Product Name: Otenabant
CAS No.: 686344-29-6
Chemical Name: Otenabant
Synonyms: CS-1072;otenabant;Otenabant, >=98%;CP945598 free base;Otenabant (CP-945,598);CP 945598;OTENABANT;CP945598;CP 945598; CP-945598; CP945598;Otenabant (CP-945598 free base);1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxamide;4-Piperidinecarboxamide, 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-
CBNumber: CB61518526
Molecular Formula: C25H25Cl2N7O
Formula Weight: 510.42
MOL File: 686344-29-6.mol

More

Less

Otenabant Property

Boiling point:: 757.9±70.0 °C(Predicted)
Density: 1.46
storage temp.: Store at -20°C
solubility: DMSO : 100 mg/mL (195.92 mM; Need ultrasonic)
form: Powder
pka: 16.30±0.20(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-1279
Product name: Otenabant
Purity: 99.33%
Packaging: 5mg
Price: $84
Updated: 2021/12/16

ChemScene

Product number: CS-1279
Product name: Otenabant
Purity: 99.33%
Packaging: 10mg
Price: $119
Updated: 2021/12/16

ApexBio Technology

Product number: A3691
Product name: Otenabant
Packaging: 10mg
Price: $156
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0006009
Product name: CP-945598
Purity: 95.00%
Packaging: 10MG
Price: $305.55
Updated: 2021/12/16

ChemScene

Product number: CS-1279
Product name: Otenabant
Purity: 99.33%
Packaging: 50mg
Price: $396
Updated: 2021/12/16

More

Less

Otenabant Chemical Properties,Usage,Production

Biological Activity

Otenabant is a potent and selective cannabinoid receptor CB1 antagonist with a Ki of 0.7 nM, more than 1000-fold selective for CB2.

in vitro

Otenabant HCl has low affinity with K _i of 7.6 μM for human CB2 receptors. It inhibits CB1 receptor with moderate unbound microsomal clearance, low hERG affinity, and adequate CNS penetration. < /p>

in vivo

Otenabant acutely stimulates energy expenditure in rats and decreases the respiratory quotient indicating a metabolic switch to increased fat oxidation. It (10 mg/kg, po) promotes a 9%, vehicle adjusted weight loss in a 10 day weight loss study in diet-induced obese mice. Otenabant HCl reverses four cannabinoid agonistmediated behaviors (locomotor activity, hypothermia, analgesia, and catalepsy) following administration of the synthetic CB1 receptor agonist CP-55940. And Otenabant HCl exhibits dose-dependent anorectic activity in a model of acute food intake in rodents and increased energy expenditure and fat oxidation.

target

Ki: 0.7 nM (CB1)

Otenabant Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Otenabant Suppliers

China 62 India 1 United States 7 Global 70

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

NCE Biomedical Co.,Ltd.

Tel: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax: +86-27-87599188
Country: China
ProdList: 1494
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Shanghai SunSyn Pharmaceutical Co., Ltd.

Tel: -2408801818 18621020637
Email: sales@sunsynpharma.com
Country: China
ProdList: 293
Advantage: 55

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

D&C Chemicals

Tel: +86-21-58447131
Fax: +86-21-61642470
Email: 1724405207@qq.com
Country: China
ProdList: 472
Advantage: 55

Twochem Co.Ltd

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 290
Advantage: 55

More

Less

View Lastest Price from Otenabant manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Otenabant 686344-29-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Otenabant 686344-29-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

686344-29-6, OtenabantRelated Search:

Chlorantraniliprole N,N-Dimethylformamide Benzamide Formamide Formamide,Deionized Hexahydroisonicotinamide Otenabant

otenabant

1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxamide

Otenabant (CP-945,598)

Otenabant, >=98%

CP945598 free base

Otenabant (CP-945598 free base)

CS-1072

CP 945598; CP-945598; CP945598

CP 945598;OTENABANT;CP945598

4-Piperidinecarboxamide, 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)-

686344-29-6

C25H25Cl2N7O