4-FLUORO-ISOINDOLINE HCL

Product Name: 4-FLUORO-ISOINDOLINE HCL
CAS No.: 924305-06-6
Chemical Name: 4-FLUORO-ISOINDOLINE HCL
Synonyms: 4-FLUORO-ISOINDOLINE HCL;4-Azetidinecarboxylicacid;Fluoroisoindoline-hydrochloride salt;4-Fluoroisoindoline hydrochloride 97%;4-Fluoro-2,3-dihydro-1H-isoindole HCl;3-Fluoro-1H-isoindoline hydrochloride;4-Fluoro-1H-isoindoline hydrochloride;4-Fluoro-2,3-dihydro-1H-isoindole hydrochloride;4-fluoro-2,3-dihydro-1H-Isoindole hydrochloride (1:1);1H-Isoindole, 4-fluoro-2,3-dihydro-, hydrochloride (1:1)
CBNumber: CB61519275
Molecular Formula: C8H9ClFN
Formula Weight: 173.62
MOL File: 924305-06-6.mol

More

Less

4-FLUORO-ISOINDOLINE HCL Property

Melting point:: 212-222℃
storage temp.: 2-8°C
form: solid
Appearance: Light brown to brown Solid
InChI: InChI=1S/C8H8FN.ClH/c9-8-3-1-2-6-4-10-5-7(6)8;/h1-3,10H,4-5H2;1H
InChIKey: MKNPYNGKUKUSFB-UHFFFAOYSA-N
SMILES: FC1C=CC=C2CNCC=12.Cl

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-26-36/37/39
RIDADR: UN 3335
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 734195
Product name: 4-Fluoroisoindoline hydrochloride
Purity: 97%
Packaging: 1g
Price: $105
Updated: 2023/06/20

TRC

Product number: F592190
Product name: 4-Fluoroisoindoline hydrochloride
Packaging: 500mg
Price: $95
Updated: 2021/12/16

TRC

Product number: F592190
Product name: 4-Fluoroisoindoline hydrochloride
Packaging: 1g
Price: $130
Updated: 2021/12/16

Matrix Scientific

Product number: 076386
Product name: 4-Fluoroisoindoline hydrochloride
Purity: 95+%
Packaging: 250mg
Price: $231
Updated: 2021/12/16

Matrix Scientific

Product number: 076386
Product name: 4-Fluoroisoindoline hydrochloride
Purity: 95+%
Packaging: 1g
Price: $500
Updated: 2021/12/16

More

Less

4-FLUORO-ISOINDOLINE HCL Chemical Properties,Usage,Production

Chemical Properties

An off-white powder

Uses

4-Fluoroisoindoline, HCl

Synthesis

685565-16-6

924305-06-6

General procedure for the synthesis of 4-fluoroisoindoline hydrochloride from the compound (CAS: 685565-16-6): to a solution of compound 3 (56 g, 0.246 mol) in methanol (300 mL) was slowly added concentrated hydrochloric acid (30 mL, 0.36 mol) and 5% Pd/C catalyst (20 g). The reaction mixture was placed under hydrogen atmosphere and stirred at room temperature for 48 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target product 4-fluoroisoindoline hydrochloride as a yellow solid (38 g, 89% yield). The product was characterized as follows: 1H NMR (300 MHz, D2O): δ 1M-1.22 (m, 1H), 7.00-7.03 (m, 1H), 6.88-6.94 (m, 1H), 4.50-4.52 (d, 4H). lc-MS: 138 (M + H)+.

References

[1] Patent: WO2009/46098, 2009, A1. Location in patent: Page/Page column 68-69

4-FLUORO-ISOINDOLINE HCL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-FLUORO-ISOINDOLINE HCL Suppliers

China 111 India 3 United States 7 Global 121

Shanghai GaoLang Chemical Technology Co., Ltd.

Tel: 021-57340939 18017297327
Fax: 021-37210791
Email: sales@gaolangchemical.com
Country: China
ProdList: 892
Advantage: 55

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Shanghai Boc Chemical Co.,Ltd

Tel: 021-34975603-808 18721111801
Fax: +86-21-34975602-805
Email: sales@bocpharma.com
Country: China
ProdList: 1009
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Shanghai Aobo pharmaceutical Technology Co., Ltd

Tel: 86-21-51320499
Fax: 86-21-51320368
Email: aobo@aobopharm.com
Country: China
ProdList: 297
Advantage: 57

More

Less

View Lastest Price from 4-FLUORO-ISOINDOLINE HCL manufacturers

Career Henan Chemical Co

Product: 4-FLUORO-ISOINDOLINE HCL 924305-06-6
Price: US $33.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2019-07-09

924305-06-6, 4-FLUORO-ISOINDOLINE HCLRelated Search:

4-(METHYLAMINO)-3-NITROPYRIDINE 4-FLUOROTHIOBENZAMIDE methyl 4-sulphamoylbenzoate 4-Fluoro-1H-indole-3-carboxylic acid methyl ester 4-FLUOROGRAMINE 2-(4-Cyclohexylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 4-FLUOROQUINOLINE 1H-INDOLE-3-CARBOXYLIC ACID,4-FLUORO- 4-Fluoroindole-2-carboxylic acid 4-(METHYLAMINO)CYCLOHEXANONE HYDROCHLORIDE 4-Chloro-1H-pyrrolo[3,2-c]pyridine 4-FLUOROPHTHALONITRILE Morpholine hydrochloride Indoline 5-Fluoroisoquinoline Isoindoline 2-(Chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride ISOINDOLIN-1-ONE

4-FLUORO-ISOINDOLINE HCL

1H-Isoindole, 4-fluoro-2,3-dihydro-, hydrochloride (1:1)

4-Fluoro-1H-isoindoline hydrochloride

3-Fluoro-1H-isoindoline hydrochloride

4-Fluoro-2,3-dihydro-1H-isoindole hydrochloride

Fluoroisoindoline-hydrochloride salt

4-Fluoroisoindoline hydrochloride 97%

4-Azetidinecarboxylicacid

4-fluoro-2,3-dihydro-1H-Isoindole hydrochloride (1:1)

4-Fluoro-2,3-dihydro-1H-isoindole HCl

924305-06-6

Building Blocks/Intermediates