2-Fluorophenylacetone
- Product Name
- 2-Fluorophenylacetone
- CAS No.
- 2836-82-0
- Chemical Name
- 2-Fluorophenylacetone
- Synonyms
- 2-FLUOROPHENYLACETONE;o-Fluorophenylacetone;2-Fluorophenylacetone99%;2-Fluorophenylacetone 99%;1-(2-Fluorophenyl)acetone;2-Fluorophenylacetone >(o-Fluorophenyl)-2-propanone;1-(2-Fluorophenyl)-2-propanone;3-(2-Fluorophenyl)-2-propanone;1-(o-Fluorophenyl)-2-propanone
- CBNumber
- CB6151942
- Molecular Formula
- C9H9FO
- Formula Weight
- 152.17
- MOL File
- 2836-82-0.mol
2-Fluorophenylacetone Property
- Boiling point:
- 47 °C/0.05 mmHg (lit.)
- Density
- 1.077 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.4989(lit.)
- Flash point:
- 185 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Methyl Acetate: 50 mg/ml
- form
- Liquid
- color
- Pale yellow
- InChI
- InChI=1S/C9H9FO/c1-7(11)6-8-4-2-3-5-9(8)10/h2-5H,6H2,1H3
- InChIKey
- BANVZEUCJHUPOI-UHFFFAOYSA-N
- SMILES
- C(C1=CC=CC=C1F)C(=O)C
- CAS DataBase Reference
- 2836-82-0(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- F0970
- Product name
- 2-Fluorophenylacetone
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $66
- Updated
- 2025/07/31
- Product number
- F0970
- Product name
- 2-Fluorophenylacetone
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $223
- Updated
- 2025/07/31
- Product number
- F595190
- Product name
- 2-Fluorophenylacetone
- Packaging
- 100g
- Price
- $1230
- Updated
- 2021/12/16
- Product number
- J97896
- Product name
- 1-(2-Fluorophenyl)propan-2-one
- Packaging
- 100g
- Price
- $350
- Updated
- 2021/12/16
- Product number
- HCH0009258
- Product name
- (2-FLUOROPHENYL)ACETONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $603.7
- Updated
- 2021/12/16
2-Fluorophenylacetone Chemical Properties,Usage,Production
Chemical Properties
clear light yellow liquid
Uses
(2-Fluorophenyl)acetone was used in the synthesis of 6-methyluracils.
Uses
2-Fluorophenylacetone is used in the synthesis of antimalarial drugs.
General Description
(2-Fluorophenyl)acetone on reaction with chlorosulfonyl isocyanate yields 5-(2-fluorophenyl)-6-methyl-1,3-oxazine-2,4-(3H)-dione.
Synthesis
829-40-3
2836-82-0
General procedure for the synthesis of 2-o-fluoropropiophenone from (2-fluorophenyl)-2-nitropropene: a suspension of 1-fluoro-2-(2-nitroprop-1-en-1-yl)benzene (2054547) (160 g, 0.88 mol), powdered iron (320 g, 5.71 mol) and ferric(III) chloride (3.2 g, 19.6 mmol) in 640 ml of water, was heated to 80°C with stirring and 37% hydrochloric acid (320 ml) was added slowly over a period of 20 min. Subsequently, the reaction mixture was heated to reflux state kept for 1 hour and then cooled to room temperature. Ethyl acetate (1 L) was added and the mixture was filtered through a diatomaceous earth pad to separate the organic and aqueous layers. The organic layer was dried and concentrated and the crude product obtained was purified by distillation under reduced pressure to give 1-(2-fluorophenyl)propan-2-one (2054549) (90 g, 67% yield) with Rf = 0.40 (ethyl acetate:heptane = 1:4) and a boiling point of 70 °C (1 mmHg).
References
[1] Patent: WO2017/29104, 2017, A1. Location in patent: Page/Page column 12
[2] Chimica Therapeutica, 1968, vol. 3, p. 313 - 320
2-Fluorophenylacetone Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluorophenylacetone Suppliers
- Tel
- --
- Fax
- --
- chemcontrol@nextra.sk
- Country
- Slovakia
- ProdList
- 6700
- Advantage
- 60
View Lastest Price from 2-Fluorophenylacetone manufacturers
- Product
- 2-Fluorophenylacetone 2836-82-0
- Price
- US $10.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2025-05-04
- Product
- 2-Fluorophenylacetone 2836-82-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10T
- Release date
- 2024-01-19
- Product
- 2-Fluorophenylacetone 2836-82-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-13