METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE

Product Name: METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE
CAS No.: 129799-08-2
Chemical Name: METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE
Synonyms: METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE;METHYL 4N-BOC-PIPERAZINE-2-CARBOXYLATE;Methyl (±)-4-Boc-piperazine-2-carboxylate;1-Boc-piperazine-3-carboxylic acid Methyl ester;N-4-BOC-2-PIPERAZINECARBOXYLIC ACID METHYL ESTER;4N-BOC-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER;1-N-Boc-piperazine-3-carboxylic acid methyl ester;4-Boc-2-Piperazinecarboxylic acid methyl ester;1-TERT-BUTYL-3-METHYL-PIPERAZINE-1,3-DICARBOXYLATE;4-N-BOC-PIPERAZINE-2-CRBOXYLIC ACID METHYL ESTER-HCl
CBNumber: CB6154983
Molecular Formula: C11H20N2O4
Formula Weight: 244.29
MOL File: 129799-08-2.mol

More

Less

METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE Property

Boiling point:: 321.3±37.0 °C(Predicted)
Density: 1.118±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Soluble in dimethyl sulfoxide.
pka: 6.45±0.40(Predicted)
Appearance: White to light yellow Solid-Liquid Mixture
InChI: InChI=1S/C11H20N2O4/c1-11(2,3)17-10(15)13-6-5-12-8(7-13)9(14)16-4/h8,12H,5-7H2,1-4H3
InChIKey: QUKAHFCVKNRRBU-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCNC(C(OC)=O)C1
CAS DataBase Reference: 129799-08-2(CAS DataBase Reference)

More

Less

Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2933599590

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B693345
Product name: 1-tert-Butyl3-MethylPiperazine-1,3-dicarboxylate
Packaging: 1g
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140578
Product name: 1-tert-Butyl 3-methyl piperazine-1,3-dicarboxylate
Packaging: 2g
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: OR308069
Product name: 1-tert-Butyl3-methylpiperazine-1,3-dicarboxylate
Purity: 97%
Packaging: 1g
Price: $53
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-321
Product name: 1-tert-Butyl 3-methyl piperazine-1,3-dicarboxylate
Purity: 97%
Packaging: 1g
Price: $58
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140578
Product name: 1-tert-Butyl 3-methyl piperazine-1,3-dicarboxylate
Packaging: 5G
Price: $80
Updated: 2021/12/16

More

Less

METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE Chemical Properties,Usage,Production

Uses

It is used as pharmaceutical intermediate.

Synthesis

126937-42-6

129799-08-2

Step 3: 10% Pd-C (0.2 equiv) was added to a stirred methanol solution of 0.1 M methyl 1-Cbz-4-Boc-2-piperazinecarboxylate (A2) and the mixture was stirred for 3 hours at room temperature under hydrogen atmosphere. After completion of the reaction, the mixture was filtered, the filter cake was washed with methanol and the filtrate was evaporated under reduced pressure to give methyl 1-BOC-3-piperazinecarboxylate (A3) in 95% yield. The product was characterized as follows: 1H NMR (400 MHz, CDCl3, 300 K) δ 4.02 (1H, m), 3.74 (3H, s), 3.70 (1H, m), 3.43 (1H, m), 3.20 (1H, m), 3.04 (2H, m), 2.75 (1H, m), 2.14 (1H, m), 1.47 (9H, s). s).MS (ES+) C11H20N2O4 theoretical value 244, measured value: 267 (M + Na)+.

References

[1] Patent: WO2010/23480, 2010, A1. Location in patent: Page/Page column 44
[2] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 23, p. 4241 - 4244
[3] Patent: WO2005/79799, 2005, A1. Location in patent: Page/Page column 18
[4] Patent: US5736539, 1998, A
[5] Patent: US6251902, 2001, B1

METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE Suppliers

China 129 Europe 2 France 2 Germany 3 India 3 United Kingdom 11 United States 38 Global 188

Lanzhou HuaHao Pharmaceutical Co., Ltd.

Tel: 18189674620
Email: 761137152@qq.com
Country: China
ProdList: 489
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Yangzhou Siyu Chemical Co.,Ltd.

Tel: 0514-87325867
Fax: 0086-514-87325867
Email: sales@siyuchem.com
Country: China
ProdList: 370
Advantage: 55

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
ProdList: 1670
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Sichuan Guanghan Bio-Tech Co., Ltd

Tel: +86-28-86127071
Fax: +86-28-86127072
Email: info@sino-produce.com
Country: China
ProdList: 406
Advantage: 66

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Tel: 21-57721279
Fax: QQ：14057904
Email: sales@shydchem.com.cn
Country: China
ProdList: 998
Advantage: 56

More

Less

View Lastest Price from METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE 129799-08-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-15

129799-08-2, METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATERelated Search:

METHYL N-4-BOC-N-1-CBZ-2-PIPERAZINECARBOXYLATE (S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE 4-Boc-1-Fmoc-2-piperazinecarboxylic acid (R)-4-N-Boc-piperazine-2-carboxylic acid methyl ester (S)-N-1-Boc-N-4-Cbz-2-piperazine carboxylic acid (S)-1-N-BOC-4-N-FMOC-PIPERAZINE-2-CARBOXYLIC ACID 1-Boc-4-Fmoc-2-piperazinecarboxylic acid (R)-N-1-BOC-N-4-CBZ-2-PIPERAZINE CARBOXYLIC ACID N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID N-1-BOC-N-4-CBZ-2-PIPERAZINE CARBOXYLIC ACID 1,4-BIS(N-BOC)PIPERAZINE-2-CARBOXYLIC ACID (S)-1-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-4-(TERT-BUTOXYCARBONYL)PIPERAZINE-2-CARBOXYLIC ACID (R)-1-N-BOC-4-N-FMOC-2-PIPERAZINE CARBOXYLIC ACID METHYL 1-BOC-PIPERAZINE-2-CARBOXYLATE (R)-N-Boc-piperazine-2-carboxylic acid methyl ester (S)-1-N-Boc-piperazine-2-carboxylic acid methyl ester 4-Boc-piperazine-2-carboxylic acid

4-N-BOC-PIPERAZINE-2-CRBOXYLIC ACID METHYL ESTER-HCl

N-4-BOC-piperazine-2-carboxylic acid Methyl ester-HCl

1-Boc-piperazine-3-carboxylic acid Methyl ester

1,3-Piperazinedicarboxylicacid, 1-(1,1-diMethylethyl) 3-Methyl ester

1-O-tert-butyl 3-O-methyl piperazine-1,3-dicarboxylate

METHYL 4-BOC-PIPERAZINE-2-CARBOXYLATE

METHYL 4N-BOC-PIPERAZINE-2-CARBOXYLATE

1-TERT-BUTYL-3-METHYL-PIPERAZINE-1,3-DICARBOXYLATE

4N-BOC-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER

N-4-BOC-2-PIPERAZINECARBOXYLIC ACID METHYL ESTER

PIPERAZINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 3-METHYL ESTER

N-T-BUTOXYCARBONYL-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER

1-N-Boc-piperazine-3-carboxylic acid methyl ester

(R)-N4-BOC-PIPERAZINE-2-CARBOXYLIC ACID METHYL ESTER

4-Boc-2-Piperazinecarboxylic acid methyl ester

Methyl (±)-4-Boc-piperazine-2-carboxylate

N-4-Boc-2-Piperazinecarboxylic acid methyl ester, CAS 129799-08-2

129799-08-2

C11H20N2O4

pharmacetical

Piperaizine