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4-Chloro-o-phenylenediamine

Product Name
4-Chloro-o-phenylenediamine
CAS No.
95-83-0
Chemical Name
4-Chloro-o-phenylenediamine
Synonyms
4-CHLORO-1,2-DIAMINOBENZENE;4-Chloro-ortho-phenylenediamine;ci76015;4-Cl-o-Pd;c.i.76015;NCI-C03292;C.I. 76015;ursololive6g;JACS-95-83-0;oro-o-phenyL
CBNumber
CB6155430
Molecular Formula
C6H7ClN2
Formula Weight
142.59
MOL File
95-83-0.mol
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4-Chloro-o-phenylenediamine Property

Melting point:
70-73 °C(lit.)
Boiling point:
232.49°C (rough estimate)
Density 
1.2124 (rough estimate)
refractive index 
1.4877 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
3.52±0.10(Predicted)
form 
Solid
color 
White to off-white
Water Solubility 
16 g/L (20 ºC)
BRN 
508472
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
BXIXXXYDDJVHDL-UHFFFAOYSA-N
CAS DataBase Reference
95-83-0(CAS DataBase Reference)
NIST Chemistry Reference
1,2-Benzenediamine, 4-chloro-(95-83-0)
IARC
2B (Vol. 27, Sup 7) 1987
EPA Substance Registry System
4-Chloro-1,2-phenylenediamine (95-83-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-40
Safety Statements 
26-36/37
RIDADR 
2811
WGK Germany 
3
RTECS 
SS8850000
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29215900
Hazardous Substances Data
95-83-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
108871
Product name
4-Chloro-o-phenylenediamine
Purity
97%
Packaging
5g
Price
$34.4
Updated
2024/03/01
Sigma-Aldrich
Product number
108871
Product name
4-Chloro-o-phenylenediamine
Purity
97%
Packaging
25g
Price
$79.9
Updated
2024/03/01
TCI Chemical
Product number
C0255
Product name
4-Chloro-1,2-phenylenediamine
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
C0255
Product name
4-Chloro-1,2-phenylenediamine
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$52
Updated
2024/03/01
Alfa Aesar
Product number
A10823
Product name
4-Chloro-o-phenylenediamine, 97%
Packaging
25g
Price
$55.6
Updated
2024/03/01
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4-Chloro-o-phenylenediamine Chemical Properties,Usage,Production

Description

4-Chloro-o-phenylene-diamine is a browncrystalline powder or leaflets from water; Freezing/Meltingpoint =67-70℃; also reported at 76℃

Chemical Properties

4-Chloro-o-phenylenediamine is a brown crystalline powder or leaflets from water; freezing/melting point 67-73°C; also reported in lit. @ 76°C. Slightly soluble in water. soluble in benzene, very soluble in ethanol, ether.

Uses

4-Chloro-o-phenylenediamine can be used as an oxidation base for dye preparation, as a chemical intermediate to produce 5-chlorobenzotriazole, as a curing agent for epoxy resins, as a reagent in gas chromatography, and to synthesize experimental pharmaceuticals. It has been used as a chemical intermediate in dye production and was patented as a hair-dye component, but there is no evidence that it is currently used in the United States for these purposes (IARC 1982, HSDB 2009).

Production Methods

Commercial production of 4-chloro-o-PDA in the United States was first reported in 1941. About 0.45–4.5 thousand kg was produced by a U.S. company in 1977. It was also produced by one company in the Federal Republic of Germany. This compound has been patented as a hair dye component, fur dyes, inks, and hair coloring formulations, and is believed to be used to produce 5-chlorobenzotriazole, an isomer of which is a photographic chemical.
The primary routes of potential human exposure to 4- chloro-o-PDA are inhalation and dermal contact during its production. Consumer exposure may occur from use of hair dyes or products made from 5-chlorobenzotriazole.

Definition

ChEBI: 4-Chloro-ortho-phenylenediamine is a member of monochlorobenzenes. Undergoes cyclizations and cyclocondensations to form benzimidazoles.

General Description

4-chloro-o-phenylenediamine appears as brown crystalline solid or powder. (NTP, 1992)

Air & Water Reactions

4-Chloro-1,2-diaminobenzene may be sensitive to prolonged exposure to air and light. Insoluble in water.

Reactivity Profile

4-Chloro-1,2-diaminobenzene is incompatible with strong oxidizers. 4-Chloro-1,2-diaminobenzene reacts with alpha-ketoacids to form quinoxalones.

Fire Hazard

Flash point data for 4-Chloro-1,2-diaminobenzene are not available. 4-Chloro-1,2-diaminobenzene is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cland NOx. See also AROMATIC AMINES.

Potential Exposure

This organochlorine material has been patented as a hair dye component. It is believed to be used in production of photographic chemicals. In varying degrees, organochlorines are absorbed from the gut and also by the lung and across the skin.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least20 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit

Carcinogenicity

4-Chloro-o-phenylenediamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity fromstudies in experimental animals.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045. Store in tightlyclosed containers in a cool, well-ventilated place or arefrigerator.

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Purification Methods

Recrystallise the diamine from pet. ether. [Beilstein 13 IV 68.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Light sensitive. It reacts with alpha-ketoacids to form quinoxalones or benzopyrazines.

Waste Disposal

Disposal of unused product must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of appropriate protective equipment. For proper handling and disposal, always comply with federal, state, and local regulations.

4-Chloro-o-phenylenediamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-o-phenylenediamine Suppliers

GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
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TCI Chemicals (India) Pvt. Ltd.
Tel
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Fax
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Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
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Alfa Aesar
Tel
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Email
tech@alfa.com
Country
India
ProdList
6905
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Clearsynth Labs
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Email
fo@clearsynth.com
Country
India
ProdList
3887
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Reax Chemicals
Tel
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Country
India
ProdList
4217
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Shree Ganesh Dye Chem
Tel
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Fax
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Country
India
ProdList
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58
K.A. Malle Pharmaceuticals Limited
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Fax
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India
ProdList
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VASIN BIO LIFE SCIENCES PVT LTD
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info@vasinbio.com
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2092
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Technichem Organics Pvt. Ltd
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Loba Chemie Pvt., Ltd.
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Chemox Chemopharma Industries
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AARTI INDUSTRIES LIMITED
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Email
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India
ProdList
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Sakam Finechem Pvt., Ltd.
Tel
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info@sakamfinechem.com
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India
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LOBA CHEMIE PVT.LTD.
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info@lobachemie.com
Country
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3075
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A.J Chemicals
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sales@ajchem.in
Country
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6100
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OCEAN TRADING CORPORATION
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Email
otcchem@otcchem.com
Country
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ProdList
6202
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View Lastest Price from 4-Chloro-o-phenylenediamine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Chloro-o-phenylenediamine 95-83-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Chloro-o-phenylenediamine 95-83-0
Price
US $30.00-10.00/kg
Min. Order
10kg
Purity
99%
Supply Ability
100000kg
Release date
2024-08-23
Henan Fengda Chemical Co., Ltd
Product
4-Chloro-o-phenylenediamine 95-83-0
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-27

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