5-Chloro-2-nitroaniline

Description Preparation

Product Name: 5-Chloro-2-nitroaniline
CAS No.: 1635-61-6
Chemical Name: 5-Chloro-2-nitroaniline
Synonyms: 5-CHLORO-2-NITROBENZENAMINE;oro-2-nitroaniL;TIMTEC-BB SBB003828;5-Chlor-2-nitroanilin;5-CHLORO-2-NITROANILINE;2-NITRO-5-CHLOROANILINE;5-Chloro-2-nitroamiline;Atorvastatin Impurity 146;Aniline, 5-chloro-2-nitro-;5-Chloro-2-nitrophenylamine
CBNumber: CB0141336
Molecular Formula: C6H5ClN2O2
Formula Weight: 172.57
MOL File: 1635-61-6.mol

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5-Chloro-2-nitroaniline Property

Melting point:: 125-129 °C (dec.)(lit.)
Boiling point:: 200°C (rough estimate)
Density: 1.5610 (rough estimate)
refractive index: 1.5870 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Chloroform, Methanol
form: Liquid
pka: -1.46±0.25(Predicted)
color: Clear colorless to light yellow
BRN: 2210201
InChIKey: ZCWXYZBQDNFULS-UHFFFAOYSA-N
CAS DataBase Reference: 1635-61-6(CAS DataBase Reference)

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Safety

Hazard Codes: T+,N,T
Risk Statements: 26/27/28-33-51/53
Safety Statements: 28-36/37-45-61-28A
RIDADR: UN 2237 6.1/PG 3
WGK Germany: 3
F: 9-23
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29214210

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 269050
Product name: 5-Chloro-2-nitroaniline
Purity: 97%
Packaging: 25g
Price: $93.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: 269050
Product name: 5-Chloro-2-nitroaniline
Purity: 97%
Packaging: 5g
Price: $55.6
Updated: 2023/06/20

TCI Chemical

Product number: C1139
Product name: 5-Chloro-2-nitroaniline
Purity: >99.0%(GC)
Packaging: 25g
Price: $49
Updated: 2024/03/01

TCI Chemical

Product number: C1139
Product name: 5-Chloro-2-nitroaniline
Purity: >99.0%(GC)
Packaging: 250g
Price: $236
Updated: 2024/03/01

Alfa Aesar

Product number: A11241
Product name: 5-Chloro-2-nitroaniline, 97%
Packaging: 25g
Price: $84.65
Updated: 2024/03/01

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5-Chloro-2-nitroaniline Chemical Properties,Usage,Production

Description

2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect.

Preparation

Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%.

Chemical Properties

yellow to orange powder

Uses

5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity.

Uses

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.

Application

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

General Description

The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

5-Chloro-2-nitroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

4-FLUORO-2-NITROBENZONITRILE 6-CHLORO-2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALINE 4-Chloro-o-phenylenediamine 2,3,6-TRICHLOROQUINOXALINE 6-CHLOROQUINOXALINE Fenbendazole

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5-Chloro-2-nitroaniline Suppliers

Americas 1 Belgium 2 Canada 2 China 257 Europe 2 Germany 4 India 15 Japan 3 Slovakia 1 Switzerland 1 Ukraine 2 United Kingdom 9 United States 32 Global 331

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.

Tel: 133-96369453 18678026865
Fax: 0536-2101172
Email: sdfantai@163.com
Country: China
ProdList: 852
Advantage: 58

Hengshui juming chemical technology co., ltd

Tel: 13785838008
Email: admin@junrunchem.com
Country: China
ProdList: 7
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2341
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2883
Advantage: 65

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
Advantage: 66

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View Lastest Price from 5-Chloro-2-nitroaniline manufacturers

Henan Fengda Chemical Co., Ltd

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-24

Nanjing Fred Technology Co., Ltd

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-28

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-24

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1635-61-6

AMINE

Building Blocks

Amines

C2 to C6

Organic Building Blocks

Nitrogen Compounds

Pyrimidines

API intermediates