Description Preparation
ChemicalBook > CAS DataBase List > 5-Chloro-2-nitroaniline

5-Chloro-2-nitroaniline

Description Preparation
Product Name
5-Chloro-2-nitroaniline
CAS No.
1635-61-6
Chemical Name
5-Chloro-2-nitroaniline
Synonyms
5-CHLORO-2-NITROBENZENAMINE;oro-2-nitroaniL;TIMTEC-BB SBB003828;5-Chlor-2-nitroanilin;5-CHLORO-2-NITROANILINE;2-NITRO-5-CHLOROANILINE;5-Chloro-2-nitroamiline;Atorvastatin Impurity 146;Aniline, 5-chloro-2-nitro-;5-Chloro-2-nitrophenylamine
CBNumber
CB0141336
Molecular Formula
C6H5ClN2O2
Formula Weight
172.57
MOL File
1635-61-6.mol
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5-Chloro-2-nitroaniline Property

Melting point:
125-129 °C (dec.)(lit.)
Boiling point:
200°C (rough estimate)
Density 
1.5610 (rough estimate)
refractive index 
1.5870 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Chloroform, Methanol
form 
Liquid
pka
-1.46±0.25(Predicted)
color 
Clear colorless to light yellow
BRN 
2210201
InChIKey
ZCWXYZBQDNFULS-UHFFFAOYSA-N
CAS DataBase Reference
1635-61-6(CAS DataBase Reference)
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Safety

Hazard Codes 
T+,N,T
Risk Statements 
26/27/28-33-51/53
Safety Statements 
28-36/37-45-61-28A
RIDADR 
UN 2237 6.1/PG 3
WGK Germany 
3
9-23
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214210
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
269050
Product name
5-Chloro-2-nitroaniline
Purity
97%
Packaging
25g
Price
$93.7
Updated
2024/03/01
Sigma-Aldrich
Product number
269050
Product name
5-Chloro-2-nitroaniline
Purity
97%
Packaging
5g
Price
$55.6
Updated
2023/06/20
TCI Chemical
Product number
C1139
Product name
5-Chloro-2-nitroaniline
Purity
>99.0%(GC)
Packaging
25g
Price
$49
Updated
2024/03/01
TCI Chemical
Product number
C1139
Product name
5-Chloro-2-nitroaniline
Purity
>99.0%(GC)
Packaging
250g
Price
$236
Updated
2024/03/01
Alfa Aesar
Product number
A11241
Product name
5-Chloro-2-nitroaniline, 97%
Packaging
25g
Price
$84.65
Updated
2024/03/01
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5-Chloro-2-nitroaniline Chemical Properties,Usage,Production

Description

2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect.

Preparation

Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%.

Chemical Properties

yellow to orange powder

Uses

5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity.

Uses

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.

Application

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

General Description

The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

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5-Chloro-2-nitroaniline Suppliers

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
854
Advantage
58
Hengshui juming chemical technology co., ltd
Tel
13785838008
Email
admin@junrunchem.com
Country
China
ProdList
7
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2964
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 5-Chloro-2-nitroaniline manufacturers

Nanjing Fred Technology Co., Ltd
Product
5-Chloro-2-nitroaniline 1635-61-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-28
WUHAN FORTUNA CHEMICAL CO., LTD
Product
5-Chloro-2-nitroaniline 1635-61-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-24
Hebei Chuanghai Biotechnology Co,.LTD
Product
5-Chloro-2-nitroaniline 1635-61-6
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2024-08-23

1635-61-6, 5-Chloro-2-nitroanilineRelated Search:


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