ChemicalBook > CAS DataBase List > 5-Chloro-2-nitroaniline

5-Chloro-2-nitroaniline

Description Preparation

Product Name: 5-Chloro-2-nitroaniline
CAS No.: 1635-61-6
Chemical Name: 5-Chloro-2-nitroaniline
Synonyms: 5-CHLORO-2-NITROBENZENAMINE;oro-2-nitroaniL;TIMTEC-BB SBB003828;5-Chlor-2-nitroanilin;5-CHLORO-2-NITROANILINE;2-NITRO-5-CHLOROANILINE;5-Chloro-2-nitroamiline;Atorvastatin Impurity 146;Aniline, 5-chloro-2-nitro-;5-Chloro-2-nitrophenylamine
CBNumber: CB0141336
Molecular Formula: C6H5ClN2O2
Formula Weight: 172.57
MOL File: 1635-61-6.mol

Less

5-Chloro-2-nitroaniline Property

Melting point:: 125-129 °C (dec.)(lit.)
Boiling point:: 200°C (rough estimate)
Density: 1.5610 (rough estimate)
refractive index: 1.5870 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Chloroform, Methanol
form: Liquid
pka: -1.46±0.25(Predicted)
color: Clear colorless to light yellow
BRN: 2210201
InChI: InChI=1S/C6H5ClN2O2/c7-4-1-2-6(9(10)11)5(8)3-4/h1-3H,8H2
InChIKey: ZCWXYZBQDNFULS-UHFFFAOYSA-N
SMILES: C1(N)=CC(Cl)=CC=C1[N+]([O-])=O
CAS DataBase Reference: 1635-61-6(CAS DataBase Reference)

Less

Safety

Hazard Codes: T+,N,T
Risk Statements: 26/27/28-33-51/53
Safety Statements: 28-36/37-45-61-28A
RIDADR: UN 2237 6.1/PG 3
WGK Germany: 3
F: 9-23
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29214210

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 269050
Product name: 5-Chloro-2-nitroaniline
Purity: 97%
Packaging: 25g
Price: $96.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 269050
Product name: 5-Chloro-2-nitroaniline
Purity: 97%
Packaging: 5g
Price: $55.6
Updated: 2023/06/20

TCI Chemical

Product number: C1139
Product name: 5-Chloro-2-nitroaniline
Purity: >99.0%(GC)
Packaging: 25g
Price: $49
Updated: 2025/07/31

TCI Chemical

Product number: C1139
Product name: 5-Chloro-2-nitroaniline
Purity: >99.0%(GC)
Packaging: 250g
Price: $236
Updated: 2025/07/31

TRC

Product number: C373770
Product name: 5-Chloro-2-nitroaniline
Packaging: 2.5g
Price: $45
Updated: 2021/12/16

Less

5-Chloro-2-nitroaniline Chemical Properties,Usage,Production

Description

2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect.

Preparation

Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%.

Chemical Properties

yellow to orange powder

Uses

5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity.

Uses

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.

Application

5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

General Description

The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.

5-Chloro-2-nitroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

4-FLUORO-2-NITROBENZONITRILE 6-CHLORO-2,3-DIOXO-1,2,3,4-TETRAHYDROQUINOXALINE 4-Chloro-o-phenylenediamine 2,3,6-TRICHLOROQUINOXALINE 6-CHLOROQUINOXALINE Fenbendazole

Less

5-Chloro-2-nitroaniline Suppliers

Americas 1 Belgium 2 Canada 2 China 270 Europe 2 Germany 4 India 15 Japan 3 Slovakia 1 Switzerland 1 Ukraine 2 United Kingdom 9 United States 32 Global 344

Hengshui juming chemical technology co., ltd

Tel: 13785838008
Email: admin@junrunchem.com
Country: China
ProdList: 7
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2806
Advantage: 65

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Junkai (Tianjin) Chemical Co., Ltd

Tel: 13920864700
Fax: +86-22-23787875
Email: sales@junkaichem.com
Country: China
ProdList: 48
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
ProdList: 2816
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3295
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
Advantage: 55

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Wuxi Zhangkun Biochemical Technology Co., Ltd.

Tel: +86 0510-85629785
Fax: +86 0510-85625359
Country: China
ProdList: 2327
Advantage: 58

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Shanghai YueChen International Trading Co. Ltd

Tel: 021-67256163
Fax: 021-67256081
Email: shanghailechen@163.com
Country: China
ProdList: 170
Advantage: 55

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai PE biochem Co.,Ltd.

Tel: +86-21-51762186
Fax: +86-21-51592879
Email: lchinsh@hotmail.com
Country: China
ProdList: 94
Advantage: 60

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 0371-0371-13526885213 15637198702
Fax: 0371-63709726
Email: hsyykjchem@163.com
Country: China
ProdList: 3853
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Mashilabs (Shanghai) Co.,Ltd.

Tel: 19916721580
Fax: QQ：3154870176
Email: mafarm@126.com
Country: China
ProdList: 4542
Advantage: 58

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.

Tel: 021-69106960 13701823733
Fax: 021-69106780
Email: 13701823733@163.com
Country: China
ProdList: 4641
Advantage: 60

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Shanghai YouPeng Chemical Co. Ltd.

Tel: 021-69005955 13701776567
Fax: 021-69005775
Email: youpengchem@163.com
Country: China
ProdList: 4161
Advantage: 56

Less

View Lastest Price from 5-Chloro-2-nitroaniline manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-24

Hebei Fengjia New Material Co., Ltd

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $4.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-08-14

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-Chloro-2-nitroaniline 1635-61-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2025-03-11

1635-61-6, 5-Chloro-2-nitroanilineRelated Search:

2-Nitroaniline 4-Chlorobenzenamine hydrochloride 3,4-Dichloroaniline 3,5-Dichloroaniline 4-Chloroaniline 5-Chloro-2-methylaniline 2-Chloroaniline 4-Nitroaniline 4-CHLORO-2-NITROANILINE 3-Chloroaniline 2,5-Dichloroaniline N-Methyl-4-nitroaniline DICHLORPHENAMIDE BULK POWDER 5-CHLORO-2-NITRODIPHENYLAMINE N1-(5-CHLORO-4-FLUORO-2-NITROPHENYL)ACETAMIDE N1-(4,5-DICHLORO-2-NITROPHENYL)ACETAMIDE 5-CHLORO-4-METHYL-2-NITROANILINE 3-CHLORO-2-NITROANILINE

TIMTEC-BB SBB003828

2-AMINO-4-CHLORO-NITROBENZENE

5-CHLORO-2-NITROANILINE

5-CHLORO-2-NITROBENZENAMINE

5-chloro-2-nitro-benzenamin

Benzenamine, 5-chloro-2-nitro-

2-NITRO-5-CHLOROANILINE

2-Amino-4-chloro-1-nitrobenzene

5-Chloro-2-nitrophenylamine

5-Chloro-2-nitroaniline ,98%

5-Chloro-2-nitroaniline,97%

5-Chloro-2-nitroaniline, 97% 50GR

5-Chloro-2-nitroaniline, 97% 5GR

5-Chlor-2-nitroanilin

5-CHLORO-2-NITROANILINE 99+%

5-Chloro-2-nitroamiline

5-CHLORO-2-NITROANILINE FOR SYNTHESIS

5-Chloro-2-nitroaniline 97%

Aniline, 5-chloro-2-nitro-

oro-2-nitroaniL

5-Chloro-2-nitroaniline &gt

5-Chloro-2-nitroaniline ISO 9001：2015 REACH

Atorvastatin Impurity 146

Febantel Impurity: 5-Chloro-2-nitroaniline

1635-61-6

AMINE

Building Blocks

Amines

C2 to C6

Organic Building Blocks

Nitrogen Compounds

Pyrimidines

API intermediates