3-(Difluoromethoxy)benzaldehyde
- Product Name
- 3-(Difluoromethoxy)benzaldehyde
- CAS No.
- 85684-61-3
- Chemical Name
- 3-(Difluoromethoxy)benzaldehyde
- Synonyms
- 3-(DIFLUOROMETHOXY)BENZALDEHYDE;Benzaldehyde,3-(difluoroMethoxy)-;3-(Difluoromethoxy)benzaldehyde98%;1-(Difluoromethoxy)-3-formylbenzene;3-(Difluoromethoxy)benzaldehyde 98%
- CBNumber
- CB6164946
- Molecular Formula
- C8H6F2O2
- Formula Weight
- 172.13
- MOL File
- 85684-61-3.mol
3-(Difluoromethoxy)benzaldehyde Property
- Boiling point:
- 80-90°C/0.3mm
- Density
- 1.300
- refractive index
- n20/D 1.496(lit.)
- Flash point:
- 107 °C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- form
- liquid
- color
- Colourless to light yellow
- Sensitive
- Air Sensitive
- CAS DataBase Reference
- 85684-61-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D452248
- Product name
- 3-(Difluoromethoxy)benzaldehyde
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- PC9371
- Product name
- 3-(Difluoromethoxy)benzaldehyde
- Purity
- 99%
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
- Product number
- 005998
- Product name
- 3-(Difluoromethoxy)benzaldehyde
- Packaging
- 1g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 007851
- Product name
- 3-(Difluoromethoxy)benzaldehyde
- Packaging
- 1g
- Price
- $25
- Updated
- 2021/12/16
- Product number
- FD64017
- Product name
- 3-(Difluoromethoxy)benzaldehyde
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
3-(Difluoromethoxy)benzaldehyde Chemical Properties,Usage,Production
Synthesis
1895-39-2
100-83-4
85684-61-3
A solution was prepared in DMF (75 mL) with sodium chlorodifluoroacetate (12.48 g, 82 mmol) and m-hydroxybenzaldehyde (5.00 g, 40.9 mmol). The solution was added dropwise to a solution of DMF (25 mL) containing potassium carbonate (8.49 g, 61.4 mmol) over a period of 3 hours, and the reaction temperature was maintained at 95 °C. After the dropwise addition, the reaction continued to be stirred at 95 °C for 2 hours. After completion of the reaction, the reaction mixture was cooled to room temperature. The reaction mixture was diluted with deionized water (100 mL) and subsequently extracted with ethyl acetate (4 x 50 mL). The organic phases were combined, washed with 10% (w/v) aqueous lithium chloride (3 x 25 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product. Purification by fast column chromatography (eluent: 15% ethyl acetate/hexane) afforded 3-(difluoromethoxy)benzaldehyde (2.50 g, 14.52 mmol, 36% yield) as a yellow oil. The nuclear magnetic resonance (NMR) spectrum of the product was consistent with the expected structure.
References
[1] Patent: WO2014/127042, 2014, A1. Location in patent: Paragraph 0471
3-(Difluoromethoxy)benzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(Difluoromethoxy)benzaldehyde manufacturers
- Product
- 3-(Difluoromethoxy)benzaldehyde 85684-61-3
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-01-09