5-Iodo-2,4-dimethoxypyrimidine

Product Name: 5-Iodo-2,4-dimethoxypyrimidine
CAS No.: 52522-99-3
Chemical Name: 5-Iodo-2,4-dimethoxypyrimidine
Synonyms: 3-METHYLPHTHALIC ACID;2,3-Toluenedicarboxylic acid;5-IODO-2,4-DIMETHOXYPYRIMIDINE;2,4-Dimethoxy-5-iodopyrimidine;Pyrimidine, 5-iodo-2,4-dimethoxy-;5-Iodo-2,4-dimethoxypyrimidine>5-Iodo-2,4-dimethoxypyrimidine ,98%;3-Methylbenzene-1,2-dicarboxylic acid;5-Iodo-2,4-dimethoxypyrimidine USP/EP/BP
CBNumber: CB6166283
Molecular Formula: C6H7IN2O2
Formula Weight: 266.04
MOL File: 52522-99-3.mol

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5-Iodo-2,4-dimethoxypyrimidine Property

Melting point:: 71-75 °C (lit.)
Boiling point:: 328.7±52.0 °C(Predicted)
Density: 1.822±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility: Chloroform; Dichloromethane
pka: 1.33±0.29(Predicted)
form: Solid
color: Off-White
Sensitive: Light Sensitive
λmax: 277 nm
InChI: 1S/C6H7IN2O2/c1-10-5-4(7)3-8-6(9-5)11-2/h3H,1-2H3
InChIKey: KNTMOGOYRYYUIE-UHFFFAOYSA-N
SMILES: COc1ncc(I)c(OC)n1
CAS DataBase Reference: 52522-99-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,T
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
HazardClass: IRRITANT, TOXIC
HS Code: 29335990
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0531
Product name: 5-Iodo-2,4-dimethoxypyrimidine
Purity: >98.0%(GC)
Packaging: 1g
Price: $95
Updated: 2025/07/31

TCI Chemical

Product number: I0531
Product name: 5-Iodo-2,4-dimethoxypyrimidine
Purity: >98.0%(GC)
Packaging: 5g
Price: $307
Updated: 2025/07/31

TRC

Product number: I706345
Product name: 5-iodo-2,4-dimethoxypyrimidine
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 021424
Product name: 5-Iodo-2,4-dimethoxypyrimidine
Purity: 98%
Packaging: 1g
Price: $26
Updated: 2021/12/16

Matrix Scientific

Product number: 021424
Product name: 5-Iodo-2,4-dimethoxypyrimidine
Purity: 98%
Packaging: 5g
Price: $83
Updated: 2021/12/16

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5-Iodo-2,4-dimethoxypyrimidine Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

3-Methylphthalic Acid is a by-product during the synthesis of 3-Methylhexahydrophthalic Anhydride (M312385), a useful reagent for the synthesis of?geometrical isomers of 1,2,3-trimethylcyclohexane. It can also be used to prepare?hydroxycarbamoyl carboxylic acids for the flotation of diaspore and aluminosilicate minerals.

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 4753, 1960 DOI: 10.1021/ja01502a085

Synthesis Reference(s)

Synthetic Communications, 18, p. 855, 1988 DOI: 10.1080/00397918808057855

Synthesis

Under nitrogen protection, 2,4-dimethoxypyrimidine (1.4 g, 10 mmol) was dissolved in tetrahydrofuran (14 mL), cooled to about 0 ??C, 1 M magnesium dichloride (2,2,6,6-tetramethylpiperidinium) lithium salt (11 mL, 11 mmol) was added dropwise with stirring, and after completion of the dropwise addition, stirring was continued for 2 hours, and then iodine (2.79 g, 11 mmol), and after maintaining the reaction at low temperature for 2 hours, it was naturally warmed back to room temperature and stirring was continued for 6 hours. The reaction solution was quenched by pouring into aqueous ammonium chloride solution, extracted three times with ethyl acetate, combined, washed, dried and concentrated. After column chromatography of the crude product obtained, 2,4-dimethoxy-5-iodopyrimidine (2.34 g, 88% yield) was obtained.

5-Iodo-2,4-dimethoxypyrimidine Preparation Products And Raw materials

Raw materials

N-Iodosuccinimide Sodium Trifluoroacetic acid 2,4-Dichloropyrimidine Sodium Methoxide Trifluoroacetic anhydride Methanol

Preparation Products

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5-Iodo-2,4-dimethoxypyrimidine Suppliers

Americas 1 China 119 Europe 1 Germany 2 India 5 Japan 1 Switzerland 1 United Kingdom 2 United States 16 Global 148

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View Lastest Price from 5-Iodo-2,4-dimethoxypyrimidine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Iodo-2,4-dimethoxypyrimidine 52522-99-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Iodo-2,4-dimethoxypyrimidine 52522-99-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 5-Iodo-2,4-dimethoxypyrimidine 52522-99-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-08

52522-99-3, 5-Iodo-2,4-dimethoxypyrimidineRelated Search:

Diphenyldimethoxysilane Metformin Dimethyl carbonate 1,1-Dimethoxyethane Dimethyldimethoxysilane 2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine Pyrimidine PYRIMITHAMINE 4,6-Dimethoxypyrimidine 5-Iodo-2-pyrimidone 2,4-Dimethoxypyrimidine 5-IODOPYRIMIDINE METHYL PYRIMIDIN-2-YL ETHER 5-Iodo-2,4-dimethoxypyrimidine

5-IODO-2,4-DIMETHOXYPYRIMIDINE

3-METHYLPHTHALIC ACID

2,4-Dimethoxy-5-iodopyrimidine

5-Iodo-2,4-dimethoxypyrimidine ,98%

2,3-Toluenedicarboxylic acid

3-Methylbenzene-1,2-dicarboxylic acid

5-Iodo-2,4-dimethoxypyrimidine&gt

Pyrimidine, 5-iodo-2,4-dimethoxy-

5-Iodo-2,4-dimethoxypyrimidine USP/EP/BP

52522-99-3

Pyrimidines

Nucleosides, Nucleotides, Oligonucleotides

Nucleoside Analogs

Heterocyclic Building Blocks

Halogenated Heterocycles

BioChemical

Biochemicals and Reagents

Building Blocks

Heterocycle-Pyrimidine series

Pyrimidine

Biochemistry

Nucleobases and their analogs

Nucleosides, Nucleotides & Related Reagents

Nucleoside Analogs

Biochemicals and Reagents

Building Blocks

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

Nucleosides

Nucleotides

Oligonucleotides

C6 to C8

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyrimidines

PyrimidinesHeterocyclic Building Blocks

Nucleoside AnalogsHeterocyclic Building Blocks

Biochemicals and Reagents

Nucleosides, Nucleotides, Oligonucleotides