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5-Iodo-2-pyrimidone

Product Name
5-Iodo-2-pyrimidone
CAS No.
79387-69-2
Chemical Name
5-Iodo-2-pyrimidone
Synonyms
5-Iodo-2-pyrimidone;5-Iodopyrimidin-2(1H);5-iodo-1H-pyrimidin-2-one;5-IodopyriMidin-2(1H)-one;2-Hydroxy-5-Iodopyrimidine;2(1H)-Pyrimidinone, 5-iodo-;5-Iodo-2(1H)-pyrimidinone, 97+%;5-Iodo-2-pyrimidone ISO 9001:2015 REACH
CBNumber
CB5947719
Molecular Formula
C4H3IN2O
Formula Weight
221.98
MOL File
79387-69-2.mol
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5-Iodo-2-pyrimidone Property

Density 
2.40±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
7.86±0.10(Predicted)
Appearance
Light brown to brown Solid
InChI
InChI=1S/C4H3IN2O/c5-3-1-6-4(8)7-2-3/h1-2H,(H,6,7,8)
InChIKey
PVHCYDBPRLPQMP-UHFFFAOYSA-N
SMILES
C1(=O)NC=C(I)C=N1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
J94974
Product name
2-Hydroxy-5-iodopyrimidine
Packaging
1g
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
118880
Product name
5-Iodopyrimidin-2(1H)-one
Purity
95+%
Packaging
1g
Price
$172
Updated
2021/12/16
AK Scientific
Product number
J94974
Product name
2-Hydroxy-5-iodopyrimidine
Packaging
5g
Price
$195
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0118915
Product name
2-HYDROXY-5-IODOPYRIMIDINE
Purity
95.00%
Packaging
5MG
Price
$501.78
Updated
2021/12/16
Matrix Scientific
Product number
118880
Product name
5-Iodopyrimidin-2(1H)-one
Purity
95+%
Packaging
5g
Price
$532
Updated
2021/12/16
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5-Iodo-2-pyrimidone Chemical Properties,Usage,Production

Synthesis

557-01-7

79387-69-2

The general procedure for the synthesis of 5-iodo-2-pyrimidinone from 2(1H)-pyrimidinone is as follows: in Example 3, 2-pyrimidinone (6 g, 62.44 mmol) and N-iodosuccinimide (14.7 g, 65.3 mmol) were dissolved in anhydrous DMF (30 ml), and stirred for 48 hr. at room temperature away from light and moisture. After completion of the reaction, the reaction mixture was slowly poured into ether (50 ml) under stirring and the supernatant was removed by decantation. The precipitate was collected by filtration and washed sequentially with acetone and methanol until the filtrate showed light yellow color. After drying under vacuum, the yellow granular product 5-iodo-2(1H)-pyrimidinone was obtained.TLC and spectral analysis showed high purity of the product, but elemental analysis indicated the presence of trace DMF contamination. The final yield was 11.35 g with 77.5% yield.

References

[1] Journal of Medicinal Chemistry, 1985, vol. 28, # 7, p. 904 - 910
[2] Patent: US4895937, 1990, A
[3] Patent: US4782142, 1988, A

5-Iodo-2-pyrimidone Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Iodo-2-pyrimidone Suppliers

Zhengzhou Alfachem Co.,Ltd.
Tel
0371-53778726 18003825608
Fax
QQ:2885354392
Email
liuxiaoyan@alfachem.cn
Country
China
ProdList
1986
Advantage
58
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
CEG Chemical Science&Technology Co., Ltd.
Tel
Mobile:13665161512
Fax
+86-510-68873513
Country
China
ProdList
1785
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58
Suzhou Laing Biological Technology Co., LTD
Tel
0512-62968256 18550502935
Fax
0512-62968256
Email
export@laingbiotec.com
Country
China
ProdList
976
Advantage
58
Nanjing YiFan Biological Technology Co., Ltd.
Tel
025-025-52700520 18914499889
Fax
025-52700520
Email
sales@yfbiotech.com
Country
China
ProdList
495
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
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View Lastest Price from 5-Iodo-2-pyrimidone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5-Iodopyrimidin-2-ol 79387-69-2
Price
US $1.10-9.90/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kg
Release date
2025-08-14
Dideu Industries Group Limited
Product
5-Iodo-2-pyrimidone 79387-69-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-06