ChemicalBook > CAS DataBase List > 2,4,5-Trifluorobenzyl bromide

2,4,5-Trifluorobenzyl bromide

Product Name
2,4,5-Trifluorobenzyl bromide
CAS No.
157911-56-3
Chemical Name
2,4,5-Trifluorobenzyl bromide
Synonyms
1-(BROMOMETHYL)-2,4,5-TRIFLUOROBENZENE;2,4,5-Trifluorobenzy;1-(Bromomethyl)-2,4,5-trifluorobenzene, alpha-Bromo-2,4,5-trifluorotoluene;5-Trifluorobenzyl broMide;2,4,5-TRIFLUOROBENZYL BROMIDE;à-bromo-2,4,5-trifluorotoluene;2,4,5-Trifluorobenzylbromide97%;2.4.5-= Fluorobromine vegetables;2,4,5-Trifluorobenzylbromide,99%;2,4,5-Trifluorobenzyl bromide 97%
CBNumber
CB6175027
Molecular Formula
C7H4BrF3
Formula Weight
225.01
MOL File
157911-56-3.mol
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2,4,5-Trifluorobenzyl bromide Property

Boiling point:
188.8±35.0 °C(Predicted)
Density 
1.71
refractive index 
1.5015
storage temp. 
Inert atmosphere,Room Temperature
form 
clear liquid
color 
Colorless to Light yellow
Specific Gravity
1.71
Sensitive 
Lachrymatory
BRN 
8312091
InChI
InChI=1S/C7H4BrF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2
InChIKey
GAUXEYCSWSMMFZ-UHFFFAOYSA-N
SMILES
C1(CBr)=CC(F)=C(F)C=C1F
CAS DataBase Reference
157911-56-3(CAS DataBase Reference)
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Safety

Hazard Codes 
C,T
Risk Statements 
34-36-25
Safety Statements 
26-36/37/39-45-23-20
RIDADR 
1760
Hazard Note 
Corrosive/Lachrymatory
TSCA 
T
HazardClass 
8
PackingGroup 
II
HS Code 
29039990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
T2386
Product name
2,4,5-Trifluorobenzyl Bromide
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
T2386
Product name
2,4,5-Trifluorobenzyl Bromide
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$168
Updated
2024/03/01
Alfa Aesar
Product number
B20066
Product name
2,4,5-Trifluorobenzyl bromide, 98%
Packaging
5g
Price
$291
Updated
2021/12/16
Alfa Aesar
Product number
B20066
Product name
2,4,5-Trifluorobenzyl bromide, 98%
Packaging
1g
Price
$80.9
Updated
2021/12/16
TRC
Product number
T896400
Product name
2,4,5-Trifluorobenzyl Bromide
Packaging
250mg
Price
$45
Updated
2021/12/16
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2,4,5-Trifluorobenzyl bromide Chemical Properties,Usage,Production

Chemical Properties

White low melting solid

Uses

2,4,5-trifluorobenzyl bromide is an important intermediate in the synthesis of Ensitrelvir (S-217622). Ensitrelvir is the latest oral drug developed by Japan's Shionogi Pharmaceutical Company to treat COVID-19. It is the first orally active, non-covalent, non-peptide SARS-CoV-23CL protease inhibitor.

Application

2,4,5-TRIFLUOROBENZYL BROMIDE is a useful research chemical.

Synthesis

Preparing 2,4,5-Trifluorobenzyl bromide, involves (a) carrying out esterification reaction on 2,4,5-trifluorobenzyl chloride and carboxylate to prepare 2,4,5-trifluorobenzyl ester, (b) hydrolyzing 2,4,5-trifluorobenzyl ester to prepare 2,4,5-trifluorobenzyl alcohol, and (c) brominating 2,4,5-trifluorobenzyl alcohol to prepare target product.

2,4,5-Trifluorobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4,5-Trifluorobenzyl bromide Suppliers

Shandong Yukun Chemical Industry Co. LTD
Tel
18660690289
Email
sales@yukunchem.com
Country
China
ProdList
45
Advantage
58
Qingzhou dafeng import and export Co. LTD
Tel
16773308882
Email
927608786@qq.com
Country
China
ProdList
3051
Advantage
58
Wuxi enqiao Pharmaceutical Technology Co., Ltd
Tel
0510-83591909 18018392058
Fax
0510-83591909
Email
info@enbridgepharm.com
Country
China
ProdList
180
Advantage
58
Beijing Huikang Boyuan Chemical Tech Co., Ltd
Tel
010-68862197 15810698817
Fax
83682022
Email
huikangqc@126.com
Country
China
ProdList
13
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
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View Lastest Price from 2,4,5-Trifluorobenzyl bromide manufacturers

Henan Fengda Chemical Co., Ltd
Product
2,4,5-Trifluorobenzyl bromide 157911-56-3
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Hebei Guanlang Biotechnology Co,.LTD
Product
2,4,5-Trifluorobenzyl bromide 157911-56-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
10 ton
Release date
2023-04-20
Hebei Guanlang Biotechnology Co., Ltd.
Product
2,4,5-Trifluorobenzyl bromide 157911-56-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-02-14

157911-56-3, 2,4,5-Trifluorobenzyl bromideRelated Search:


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