Bis(2-oxo-3-oxazolidinyl)phosphinic chloride

Product Name: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
CAS No.: 68641-49-6
Chemical Name: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
Synonyms: BOP-CL;BOP-CI;BOP-C;BOPDC;idinyL;BIS(2-OXO-3-OX;Phosphoric acid bi;Bis(2-oxo-3-oxazoL;Bis(2-oxo-3-oxazolid;bis(2-oxo-3-oxazolidinyl)-phosphinicchlorid
CBNumber: CB6177768
Molecular Formula: C6H8ClN2O5P
Formula Weight: 254.56
MOL File: 68641-49-6.mol

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Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Property

Melting point:: 191 °C (dec.)(lit.)
Boiling point:: 332.8±25.0 °C(Predicted)
Density: 1.71±0.1 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
solubility: slightly sol CH2Cl2, MeCN, THF, DMF; dec H2O
pka: -2.47±0.20(Predicted)
form: Crystalline Powder
color: White to off-white
Water Solubility: Hydrolyzes with water.
Sensitive: Moisture Sensitive
BRN: 3654596
InChI: InChI=1S/C6H8ClN2O5P/c7-15(12,8-1-3-13-5(8)10)9-2-4-14-6(9)11/h1-4H2
InChIKey: KLDLRDSRCMJKGM-UHFFFAOYSA-N
SMILES: P(N1CCOC1=O)(N1CCOC1=O)(Cl)=O
CAS DataBase Reference: 68641-49-6(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45-27
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
RTECS: SZ5871000
F: 10-21
HazardClass: 8
PackingGroup: II
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 15140
Product name: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
Purity: ≥97.0% (AT)
Packaging: 5g
Price: $93.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 15140
Product name: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
Purity: ≥97.0% (AT)
Packaging: 25g
Price: $366
Updated: 2025/07/31

TCI Chemical

Product number: B1213
Product name: Bis(2-oxo-3-oxazolidinyl)phosphinic Chloride
Purity: >97.0%(T)
Packaging: 5g
Price: $39
Updated: 2025/07/31

TCI Chemical

Product number: B1213
Product name: Bis(2-oxo-3-oxazolidinyl)phosphinic Chloride
Purity: >97.0%(T)
Packaging: 25g
Price: $131
Updated: 2025/07/31

TRC

Product number: O990150
Product name: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride
Packaging: 500mg
Price: $75
Updated: 2021/12/16

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Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Chemical Properties,Usage,Production

Description

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride is a reagent for activating carboxyl groups, converting acids to esters (including thioesters and phosphoesters), amides (including peptides and β-lactams), and anhydrides; reagent for kinetic resolution of racemic carboxylic acids and alcohols.

Chemical Properties

White solid

Uses

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride was used in the preparation of hexadepsipeptide.

storage

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride should store in a cool dry place under nitrogen to preclude contact with moisture and oxygen. Use only in a chemical fume hood. Wear suitable protective clothing and eye/face protection. Causes burns and is harmful if swallowed, inhaled, or absorbed through skin.

Purification Methods

the outcome of reactions can be greatly affected by the purity of the reagent; commercial samples may require to be washed with cold water and recrystallized from MeCN prior to use.

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis(2-oxo-3-oxazolidinyl)phosphinic chloride Suppliers

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View Lastest Price from Bis(2-oxo-3-oxazolidinyl)phosphinic chloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride 68641-49-6
Price: US $0.00/G
Min. Order: 100G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-08

Henan Aochuang Chemical Co.,Ltd.

Product: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride 68641-49-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-26

Shaanxi Dideu New Materials Co. Ltd

Product: Bis(2-oxo-3-oxazolidinyl)phosphinic chloride 68641-49-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-22

68641-49-6, Bis(2-oxo-3-oxazolidinyl)phosphinic chlorideRelated Search:

Choline chloride Phosphorus oxybromide Calcium chloride Sodium chloride Ammonium chloride Acetyl chloride Polyvinyl chloride Benzyl chloride Bicyclo[1.1.1]pentane-1,3-dicarboxylic acid, MonoMethyl ester Phosphorus oxitrichloride Potassium chloride DIMETHYL-P-NITROPHENYLPHOSPHATE PARAOXON Ammonium carbonate additive AMMONIUM CARBAMATE Methylene Chloride BIS(DIMETHYLAMINO)PHOSPHORYL CHLORIDE 2-Oxazolidone

bis(2-oxo-3-oxazolidinyl)-phosphinicchlorid

PHOSPHORIC ACID BIS(2-OXOOXAZOLIDIDE) CHLORIDE

N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE

N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHONIC CHLORIDE

N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORODIAMIDIC CHLORIDE

Bis(2-oxo-3-oxazolid

Phosphoric acid bi

Phosphoric acid bis(2-oxooxazolidide) chloride(BOP-Cl)

BIS(2-OXO-3-OX

Bis(2-oxo-1,3-oxazolidin-3-yl)phosphinic chloride

N,N-Bis(2-oxo-3-oxazolidinyl)phosphinic chloride≥ 98% (Assay)

Bis(2-oxooxazolidin-3-yl)phosphinic chloride

Double(2-oxo -3-oxazolaM)phosphinic chloride

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride >=97.0% (AT)

BOP-Cl Bis(2-oxo-3-oxazolidinyl)phosphonic chloride

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 97% 5GR

Phosphinic chloride,P,P-bis(2-oxo-3-oxazolidinyl)-

BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE

BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHONIC CHLORIDE

BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORODIAMIDIC CHLORIDE

BOP-CI

BOP-CL

BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE (BOP-CL)

N,N-BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHORAMIDIC CHLORIDE

BOP-CL BIS(2-OXO-3-OXAZOLIDINYL)PHOSPHINIC CHLORIDE

Bis-(2-oxo-3-oxazolidinyl)-phosphinyl chloride

3,3'-(Chlorophosphinylidene)bis(oxazolidine-2-one)

3,3'-(Chlorophosphonoyl)bis(oxazolidine-2-one)

3,3'-(Oxochlorophosphoranylidene)bis(oxazolidine-2-one)

3,3'-Chlorophosphinylidenebis(oxazolidine-2-one)

Bis(2-oxo-3-oxazolidinyl)chlorophosphine oxide

Bis(2-oxo-3-oxazolidinyl)phosphinic acidchloride

BOP-Cl, Phosphoric acid bis(2-oxooxazolidide) chloride

3-[Chloro-(2-oxo-1,3-oxazolidin-3-yl)phosphoryl]-1,3-oxazolidin-2-one

BOP-C

BOPDC

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride ,97%

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride, 97%, for synthesis

Bis(2-oxo-3-oxazolidinyl)phosphinic Chloride &gt

Bis(2-oxo-3-oxazoL

idinyL

Bis(2-oxo-3-oxazolidinyl)phosphinic chloride USP/EP/BP

3-[chloro-(2-oxooxazolidin-3-yl)phosphoryl]oxazolidin-2-one

68641-49-6

C8H8ClN2O5P

C6H8ClN2O5P

Building Blocks

Heterocyclic Building Blocks

Oxazolines/Oxazolidines

Coupling Reactions (Peptide Synthesis)

Peptide Synthesis

Condensation & Active Esterification

Coupling Reagent

Peptide coupling agents

Biochemistry

Condensation & Active Esterification

Coupling Reactions (Peptide Synthesis)

Peptide Synthesis