6-Methylindole Property

Melting point:

29-32°C

Boiling point:

112 °C/5 mmHg (lit.)

Density 

1.059 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.607(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

pka

17.36±0.30(Predicted)

form 

Liquid After Melting

Specific Gravity

1.059

color 

Clear yellow to light brown

Water Solubility 

Insoluble in water.

Sensitive 

Light Sensitive

BRN 

109708

InChIKey

ONYNOPPOVKYGRS-UHFFFAOYSA-N

LogP

2.600 (est)

CAS DataBase Reference

3420-02-8(CAS DataBase Reference)

NIST Chemistry Reference

1H-Indole, 6-methyl-(3420-02-8)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 3334

WGK Germany 

3

Hazard Note 

Light Sensitive/Irritant/Keep Cold

HazardClass 

IRRITANT, LIGHT SENSITIVE

HS Code 

29339900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

6-Methylindole Chemical Properties,Usage,Production

Chemical Properties

clear yellow to light brown liquid after melting

Uses

6-Methylindole was used in the synthesis of benz[c,d]indol-3(1H)-one derivatives.
Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
Reactant for preparation of indole linked triazole derivatives as antifungal agents
Reactant for preparation of N-β-D-xylosyl-indole derivatives as SGLT2 inhibitors for management of hyperglycemia in diabetes
Reactant for preparation of aminoguanidine derivatives of arylsulfonylacylindoles as antifungal agents
Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors
Reactant for preparation of arylsulfonylacetylindoles as anti-HIV-1 agents