Fenclorim
- Product Name
- Fenclorim
- CAS No.
- 3740-92-9
- Chemical Name
- Fenclorim
- Synonyms
- Soft;SOFIT;enclorim;femclorim;FENCLORIM;NSC 27713;fenclorime;cga-123407;fenchlorim;Jiecaoding
- CBNumber
- CB6187251
- Molecular Formula
- C10H6Cl2N2
- Formula Weight
- 225.07
- MOL File
- 3740-92-9.mol
Fenclorim Property
- Melting point:
- 92-93°C
- Boiling point:
- 235.5±33.0 °C(Predicted)
- Density
- 1.363±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)
- pka
- -4.69±0.30(Predicted)
- color
- Off-White to Pale Yellow
- Water Solubility
- Insoluble in water
- BRN
- 142293
- InChI
- InChI=1S/C10H6Cl2N2/c11-8-6-9(12)14-10(13-8)7-4-2-1-3-5-7/h1-6H
- InChIKey
- NRFQZTCQAYEXEE-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=CC=C2)=NC(Cl)=CC(Cl)=N1
- CAS DataBase Reference
- 3740-92-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H317May cause an allergic skin reaction
H318Causes serious eye damage
H332Harmful if inhaled
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 46005
- Product name
- Fenclorim
- Purity
- PESTANAL
- Packaging
- 250mg
- Price
- $83.8
- Updated
- 2022/05/15
- Product number
- F0851
- Product name
- Fenclorim
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $78
- Updated
- 2025/07/31
- Product number
- F0851
- Product name
- Fenclorim
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $233
- Updated
- 2025/07/31
- Product number
- F247500
- Product name
- Fenclorim
- Packaging
- 10g
- Price
- $245
- Updated
- 2021/12/16
- Product number
- F0045-95
- Product name
- Fenclorim
- Packaging
- 5g
- Price
- $403
- Updated
- 2021/12/16
Fenclorim Chemical Properties,Usage,Production
Description
Fenclorim (4,6-dichloro-2-phenylpyrimidine) is a pyrimidine herbicide safener that effectively protects rice (Oryza sativa L.) from the phytotoxicity of certain herbicides. It improves rice tolerance to chloroacetanilide herbicides by enhancing the expression of detoxifying glutathione S-transferase (GST). Compared with seed treatment with safener alone, sequential seed treatment with safener and insecticide minimizes the release of fenclorim without causing residue problems in the ecosystem and harvested rice.
Chemical Properties
White to off-white solid
Uses
Herbicide safener.
Definition
ChEBI: Fenclorim is a member of pyrimidines and an organohalogen compound.
Synthesis
13566-71-7
3740-92-9
The general procedure for the synthesis of 4,6-dichloro-2-phenyl-pyrimidine from 2-phenylpyrimidine-4,6-diol was as follows: 300 ml of phosphoryl chloride was added to 40 g of 2-phenylpyrimidine-4,6-diol. The reaction mixture was heated to reflux at 100 °C for 48 hours. Upon completion of the reaction, the excess phosphoryl chloride was removed by distillation under reduced pressure (20 mbar). Subsequently, 200 ml of chloroform and 100 ml of ice water were added to the reaction mixture and stirred thoroughly for 30 minutes. The pH of the mixture was adjusted to 5-6 with aqueous sodium carbonate. the organic layer was separated and the aqueous phase was extracted three times with 200 mL of chloroform. All chloroform phases were combined, dried with magnesium sulfate, filtered and the chloroform was removed by evaporation under reduced pressure. The resulting crude product can be purified by distillation under reduced pressure or by column chromatography using 60 mesh silica gel (with chloroform as eluent).
References
[1] Patent: US2003/162764, 2003, A1
[2] Bulletin of the Korean Chemical Society, 2012, vol. 33, # 8, p. 2627 - 2634
[3] Patent: US6372751, 2002, B1. Location in patent: Example Pr3
[4] Australian Journal of Chemistry, 2015, vol. 68, # 5, p. 814 - 824
[5] Farmaco, 1997, vol. 52, # 1, p. 61 - 65
Fenclorim Preparation Products And Raw materials
Raw materials
Preparation Products
Fenclorim Suppliers
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View Lastest Price from Fenclorim manufacturers
- Product
- Fenclorim 3740-92-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 20tons
- Release date
- 2025-09-28
- Product
- fenclorim 3740-92-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- EX:100 tons
- Release date
- 2025-05-27
- Product
- Fenclorim 3740-92-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/10kg/100kg
- Release date
- 2020-10-29