Pristinamycin IA

Product Name: Pristinamycin IA
CAS No.: 3131-03-1
Chemical Name: Pristinamycin IA
Synonyms: PA 114B;NSC 92554;mikamycin B;MikaMycin IA;Ostreogrycin B;VirginiaMycin B;Streptogramin B;Pristinamycin IA;Pristinamycin ⅠA;PristinaMycin P 1
CBNumber: CB62079233
Molecular Formula: C45H54N8O10
Formula Weight: 866.96
MOL File: 3131-03-1.mol

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Pristinamycin IA Property

Melting point:: 198°
alpha: D22 -57.5° (c = 0.25 in ethanol)
Boiling point:: 780.3°C (rough estimate)
Density: 1.1881 (rough estimate)
refractive index: 1.6910 (estimate)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: pKa 7.20±0.05(H2O,t =25,I=0.2(LiClO4)) (Uncertain)
color: Pale Yellow

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Safety

RIDADR: 3172
HazardClass: 6.1(b)
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28086
Product name: Streptogramin B
Packaging: 1mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 28086
Product name: Streptogramin B
Packaging: 25mg
Price: $1075
Updated: 2024/03/01

Cayman Chemical

Product number: 28086
Product name: Streptogramin B
Packaging: 5mg
Price: $253
Updated: 2024/03/01

Cayman Chemical

Product number: 28086
Product name: Streptogramin B
Packaging: 10mg
Price: $468
Updated: 2024/03/01

Usbiological

Product number: V2122-82A
Product name: Virginiamycin B
Packaging: 5mg
Price: $513
Updated: 2021/12/16

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Pristinamycin IA Chemical Properties,Usage,Production

Uses

Virginiamycin B is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a syngergistic mixture. Virginiamycin B, also known as ostreogrycin B and streptogramin B among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature. Viriginiamycin B acts a syngergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.

Uses

One of the two major components of Pristinamycin (Pristinamycin IA and Pristinamycin IIA (or Virginiamycin M1-V673810).

Definition

ChEBI: A cyclodepsipeptide that is (together with pristinamycin IIA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organis s including methicillin-resistant Staphylococcus aureus.

Contact allergens

Pristinamycin is a systemic antibiotic of the synergistins/ streptogramins class, composed of two subunits: pristinamycin IA and pristinamycin IIA. It induces several types of drug reactions such as maculo-papular exanthema, systemic dermatitis, or acute generalized exanthematous pustulosis. Some patients have been previously skin-sensitized by virginiamycin. Crossreactivity is expected to virginiamycin and to the associated dalfopristin and quinupristin.

Pristinamycin IA Preparation Products And Raw materials

Raw materials

Preparation Products

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Pristinamycin IA Suppliers

Canada 1 China 33 India 1 United Kingdom 1 United States 9 Global 45

MedChemexpress LLC

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Musechem

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TargetMol Chemicals Inc.

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BOC Sciences

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Aladdin Scientific

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Cayman Chemical Company

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United States Biological

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MedChemExpress

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View Lastest Price from Pristinamycin IA manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Pristinamycin IA 3131-03-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-07-07

3131-03-1, Pristinamycin IARelated Search:

Procyanidin Procyanidin B1 VIRGINIAMYCIN M1 PROCYANIDIN B2 Clindamycin Enalapril Lisinopril Dihydrate Captopril Daptomycin Gentamicin Virginiamycin

N-[(3-Hydroxy-2-pyridinyl)carbonyl]-L-threonyl-(2R)-2-aMinobutanoyl-L-prolyl-4-(diMethylaMino)-N-Methyl-L-phenylalanyl-(2S)-4-oxo-2-piperidinecarbonyl-(2S)-2-phenylglycine (6-13)-lactone

NSC 92554

PA 114B

PristinaMycin P 1

Ostreogrycin B, PristinaMycin IA, StreptograMin B, Syncothrecin B1, Synergistin B, VernaMycin Balpha, VirginiaMycin 1A, NSC 125176, 14725-1, PA 114B, RP 12535

VirginiaMycin B

Pristinamycin IA, >95%

mikamycin B

N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo(L-Thr*-D-Abu-L-Pro-N-methyl-4-(dimethylamino)-L-Phe-4-oxo-L-2-piperidinecarbonyl-L-phenyl Gly-)

Ostreogrycin B

Pristinamycin IA

Streptogramin B

PristinaMycin IA DISCONTINUED

4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]virginiaMycin S1

Antibiotic PA 114B

Antibiotic PA 114B1

MikaMycin IA

Virginiamycin S1, 4-[4-(dimethylamino)-N-methyl-L-phenylalanine]-

Antibiotic,ribosome,Bacterial,macrolactone,vinblastine,inhibit,Pristinamycin IA,Inhibitor,P-glycoprotein

Pristinamycin ⅠA

3131-03-1

131-03-1

C45H54N8O10

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals