ChemicalBook > CAS DataBase List > (-)-PINORESINOL

(-)-PINORESINOL

Product Name
(-)-PINORESINOL
CAS No.
81446-29-9
Chemical Name
(-)-PINORESINOL
Synonyms
()-Pinoresinol;(-)-PINORESINOL;(-)-Pinoresinol, 10 mM in DMSO;Phenol, 4,4'-[(1R,3aS,4R,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2-methoxy-;4-[(3R,3aS,6R,6aS)-6-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
CBNumber
CB6220091
Molecular Formula
C20H22O6
Formula Weight
358.39
MOL File
Mol file
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(-)-PINORESINOL Property

Melting point:
119-120 °C
Boiling point:
556.5±50.0 °C(Predicted)
Density 
1.287±0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
9.54±0.35(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN92287
Product name
(-)-Pinoresinol
Purity
≥98%
Packaging
5mg
Price
$268
Updated
2021/12/16
Crysdot
Product number
CD32000348
Product name
(-)-Pinoresinol
Purity
95+%
Packaging
5mg
Price
$440
Updated
2021/12/16
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(-)-PINORESINOL Chemical Properties,Usage,Production

Uses

(-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest[1].

Definition

ChEBI: (-)-pinoresinol is an enantiomer of pinoresinol having (-)-1R,3aS,4R,6aS-configuration. It has a role as a plant metabolite.

target

TNF-α | COX | NF-kB | NOS | AP-1 | JNK | CDK | p21

References

[1] Lucia Fini, et al. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis. 2008 Jan;29(1):139-46. DOI:10.1093/carcin/bgm255
[2] Alexandrine During, et al. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J Nutr. 2012 Oct;142(10):1798-805. DOI:10.3945/jn.112.162453

(-)-PINORESINOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (-)-PINORESINOL manufacturers

Shanghai Standard Technology Co., Ltd.
Product
(-)-Pinoresinol 81446-29-9
Price
US $0.00/mg
Min. Order
5mg
Purity
≥97%(HPLC)
Supply Ability
10 g
Release date
2020-05-07
Career Henan Chemical Co
Product
(-)-PINORESINOL 81446-29-9
Price
US $8.00/KG
Min. Order
1g
Purity
>98% HPLC
Supply Ability
kg--ton
Release date
2020-02-20

81446-29-9, (-)-PINORESINOLRelated Search:


  • (-)-PINORESINOL
  • Phenol, 4,4'-[(1R,3aS,4R,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2-methoxy-
  • 4-[(3R,3aS,6R,6aS)-6-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol
  • ()-Pinoresinol
  • (-)-Pinoresinol, 10 mM in DMSO
  • 81446-29-9