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2'-Hydroxy-5'-methoxyacetophenone

Product Name
2'-Hydroxy-5'-methoxyacetophenone
CAS No.
705-15-7
Chemical Name
2'-Hydroxy-5'-methoxyacetophenone
Synonyms
1-(2-HYDROXY-5-METHOXYPHENYL)ETHAN-1-ONE;1-(2-HYDROXY-5-METHOXYPHENYL)ETHANONE;2-HYDROXY-5-METHOXYACETOPHENONE;Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-;2'-Hydro;NSC 338218;ASISCHEM D38760;sulfosulfamic acid;5-Methoxy-2-hydroxyacetophenone;2'-Hydroxy-5'-methoxyacetophene
CBNumber
CB6234562
Molecular Formula
C9H10O3
Formula Weight
166.17
MOL File
705-15-7.mol
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2'-Hydroxy-5'-methoxyacetophenone Property

Melting point:
52 °C(lit.)
Boiling point:
254.38°C (rough estimate)
Density 
1.1708 (rough estimate)
refractive index 
1.5500 (estimate)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Crystalline Powder
pka
10.65±0.18(Predicted)
color 
Yellow
Odor
Aromatic, somewhat medicinal, warm, woody -the herbaceous odour of good tenacity.
BRN 
1239364
InChIKey
MLIBGOFSXXWRIY-UHFFFAOYSA-N
CAS DataBase Reference
705-15-7(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-(705-15-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-36/37/38
Safety Statements 
26-37/39-36/37/39-22
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29145090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
114995
Product name
2′-Hydroxy-5′-methoxyacetophenone
Purity
99%
Packaging
5g
Price
$65.2
Updated
2024/03/01
Sigma-Aldrich
Product number
114995
Product name
2′-Hydroxy-5′-methoxyacetophenone
Purity
99%
Packaging
25g
Price
$94.2
Updated
2024/03/01
TCI Chemical
Product number
H0868
Product name
2'-Hydroxy-5'-methoxyacetophenone
Purity
>98.0%(GC)
Packaging
5g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
H0868
Product name
2'-Hydroxy-5'-methoxyacetophenone
Purity
>98.0%(GC)
Packaging
25g
Price
$130
Updated
2024/03/01
Alfa Aesar
Product number
A19216
Product name
2'-Hydroxy-5'-methoxyacetophenone, 99%
Packaging
5g
Price
$47.65
Updated
2024/03/01
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2'-Hydroxy-5'-methoxyacetophenone Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols. 2-Hydroxy-5-methoxyacetophenone is also used to prepare substituted chromanone and chromone derivatives as sirtuin 2-selective inhibitors.

Application

2'-Hydroxy-5'-methoxyacetophenone could find some use in perfume compositions, e. g., in artificial Oakmoss, in New Mown Hay fragrances, and in certain heavy florals. It blends well with Labdanum and with Lavender type oils, and it lends a certain amount of power and undertones to the fragrance.

Preparation

reparation by reaction of dimethyl sulfate on 2,5-dihydroxyacetophenone, ? with potassium carbonate in acetone at r.t. (74%) ; ? with aqueous sodium hydroxide solution at reflux (35%).

Synthesis Reference(s)

Synthesis, p. 901, 1985 DOI: 10.1055/s-1985-31380

General Description

2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols.

2'-Hydroxy-5'-methoxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Hydroxy-5'-methoxyacetophenone Suppliers

Americas 1 Austria 1 Belgium 3 Canada 1 China 168 Czech Republic 1 Europe 1 Germany 5 India 34 Japan 4 Slovakia 1 Switzerland 3 The Netherlands 1 Ukraine 2 United Kingdom 15 United States 40 USA 1 Global 282
R&D Scientific Inc.
Tel
+1-2266000236
Email
sales@rdscientific.com
Country
Canada
ProdList
1603
Advantage
58
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View Lastest Price from 2'-Hydroxy-5'-methoxyacetophenone manufacturers

R&D Scientific Inc.
Product
2'-Hydroxy-5'-methoxyacetophenone 705-15-7
Price
US $950.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-04-23
Career Henan Chemical Co
Product
2'-Hydroxy-5'-methoxyacetophenone 705-15-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2018-08-09

705-15-7, 2'-Hydroxy-5'-methoxyacetophenoneRelated Search:

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  • 5-Methoxy-2-hydroxyacetophenone
  • Acetophenone, 2'-hydroxy-5'-methoxy-
  • 1-(2-HYDROXY-5-METHOXYPHENYL)ETHAN-1-ONE
  • 1-(2-HYDROXY-5-METHOXYPHENYL)ETHANONE
  • 2'-HYDROXY-5'-METHOXYACETOPHENONE
  • 2-HYDROXY-5'-METHOXYACETOPHENONE
  • 2-HYDROXY-5-METHOXYACETOPHENONE
  • 2'-HYDROXY-5'-METHOXYACETYLPHENONE
  • ASISCHEM D38760
  • 2'-Hydroxy-5'-methoxyacetophenone 99%
  • NSC 338218
  • 2'-HYDROXY-5'-METHOXYACETOPHENONE,99%
  • 2'-Hydro
  • 2'-Hydroxy-5'-methoxyacetophene
  • JR-6832, 1-(2-Hydroxy-5-methoxyphenyl)ethanone, 97%
  • sulfosulfamic acid
  • 2'-Hydroxy-5'-methoxyacetophenone&gt
  • Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-
  • 2'-Hydroxy-5'-methoxyacetophenone
  • 705-15-7
  • Building Blocks
  • Carbonyl Compounds
  • C9
  • Ketones
  • Organic Building Blocks
  • ketone| alcohol
  • Aromatic Acetophenones & Derivatives (substituted)
  • C9
  • Carbonyl Compounds
  • Ketones