2'-Hydroxy-5'-methoxyacetophenone

ChemicalBook > CAS DataBase List > 2'-Hydroxy-5'-methoxyacetophenone

2'-Hydroxy-5'-methoxyacetophenone

Product Name: 2'-Hydroxy-5'-methoxyacetophenone
CAS No.: 705-15-7
Chemical Name: 2'-Hydroxy-5'-methoxyacetophenone
Synonyms: 1-(2-HYDROXY-5-METHOXYPHENYL)ETHAN-1-ONE;1-(2-HYDROXY-5-METHOXYPHENYL)ETHANONE;2-HYDROXY-5-METHOXYACETOPHENONE;Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-;2'-Hydro;NSC 338218;ASISCHEM D38760;sulfosulfamic acid;5-Methoxy-2-hydroxyacetophenone;2'-Hydroxy-5'-methoxyacetophene
CBNumber: CB6234562
Molecular Formula: C9H10O3
Formula Weight: 166.17
MOL File: 705-15-7.mol

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2'-Hydroxy-5'-methoxyacetophenone Property

Melting point:: 52 °C(lit.)
Boiling point:: 254.38°C (rough estimate)
Density: 1.1708 (rough estimate)
refractive index: 1.5500 (estimate)
Flash point:: >230 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Crystalline Powder
pka: 10.65±0.18(Predicted)
color: Yellow
Odor: Aromatic, somewhat medicinal, warm, woody -the herbaceous odour of good tenacity.
BRN: 1239364
InChIKey: MLIBGOFSXXWRIY-UHFFFAOYSA-N
CAS DataBase Reference: 705-15-7(CAS DataBase Reference)
NIST Chemistry Reference: Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-(705-15-7)

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41-36/37/38
Safety Statements: 26-37/39-36/37/39-22
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29145090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 114995
Product name: 2′-Hydroxy-5′-methoxyacetophenone
Purity: 99%
Packaging: 5g
Price: $65.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: 114995
Product name: 2′-Hydroxy-5′-methoxyacetophenone
Purity: 99%
Packaging: 25g
Price: $94.2
Updated: 2024/03/01

TCI Chemical

Product number: H0868
Product name: 2'-Hydroxy-5'-methoxyacetophenone
Purity: >98.0%(GC)
Packaging: 5g
Price: $29
Updated: 2024/03/01

TCI Chemical

Product number: H0868
Product name: 2'-Hydroxy-5'-methoxyacetophenone
Purity: >98.0%(GC)
Packaging: 25g
Price: $130
Updated: 2024/03/01

Alfa Aesar

Product number: A19216
Product name: 2'-Hydroxy-5'-methoxyacetophenone, 99%
Packaging: 5g
Price: $47.65
Updated: 2024/03/01

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2'-Hydroxy-5'-methoxyacetophenone Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols. 2-Hydroxy-5-methoxyacetophenone is also used to prepare substituted chromanone and chromone derivatives as sirtuin 2-selective inhibitors.

Application

2'-Hydroxy-5'-methoxyacetophenone could find some use in perfume compositions, e. g., in artificial Oakmoss, in New Mown Hay fragrances, and in certain heavy florals. It blends well with Labdanum and with Lavender type oils, and it lends a certain amount of power and undertones to the fragrance.

Preparation

reparation by reaction of dimethyl sulfate on 2,5-dihydroxyacetophenone, ? with potassium carbonate in acetone at r.t. (74%) ; ? with aqueous sodium hydroxide solution at reflux (35%).

Synthesis Reference(s)

Synthesis, p. 901, 1985 DOI: 10.1055/s-1985-31380

General Description

2′-Hydroxy-5′-methoxyacetophenone is observed as a side reaction product of elbs persulphate oxidation of phenols.

2'-Hydroxy-5'-methoxyacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Hydroxy-5'-methoxyacetophenone Suppliers

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View Lastest Price from 2'-Hydroxy-5'-methoxyacetophenone manufacturers

R&D Scientific Inc.

Product: 2'-Hydroxy-5'-methoxyacetophenone 705-15-7
Price: US $950.00/Kg
Min. Order: 1Kg
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-04-23

Career Henan Chemical Co

Product: 2'-Hydroxy-5'-methoxyacetophenone 705-15-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-08-09

705-15-7, 2'-Hydroxy-5'-methoxyacetophenoneRelated Search:

4'-Hydroxyacetophenone PIPERACETAZINE (250 MG) 2'-Methoxyacetophenone CHLOROPHOSPHONAZO III 3-Methoxyacetophenone 2',4'-Dichloroacetophenone 3-Aminoacetophenone 3',5'-Dimethoxyacetophenone 4-Nitroacetophenone 4'-Methoxyacetophenone 3,4-Dimethoxyacetophenone 2-HYDROXYACETOPHENONE Acetophenone 2'-Hydroxyacetophenone 3-Nitroacetophenone 2-BROMO-2',5'-DIMETHOXYACETOPHENONE EUPATORIN-5-METHYL ETHER 4',6,7-Trimethoxyisoflavone

5-Methoxy-2-hydroxyacetophenone

Acetophenone, 2'-hydroxy-5'-methoxy-

1-(2-HYDROXY-5-METHOXYPHENYL)ETHAN-1-ONE

1-(2-HYDROXY-5-METHOXYPHENYL)ETHANONE

2'-HYDROXY-5'-METHOXYACETOPHENONE

2-HYDROXY-5'-METHOXYACETOPHENONE

2-HYDROXY-5-METHOXYACETOPHENONE

2'-HYDROXY-5'-METHOXYACETYLPHENONE

ASISCHEM D38760

2'-Hydroxy-5'-methoxyacetophenone 99%

NSC 338218

2'-HYDROXY-5'-METHOXYACETOPHENONE,99%

2'-Hydro

2'-Hydroxy-5'-methoxyacetophene

JR-6832, 1-(2-Hydroxy-5-methoxyphenyl)ethanone, 97%

sulfosulfamic acid

2'-Hydroxy-5'-methoxyacetophenone&gt

Ethanone, 1-(2-hydroxy-5-methoxyphenyl)-

2'-Hydroxy-5'-methoxyacetophenone

705-15-7

Building Blocks

Carbonyl Compounds

Ketones

Organic Building Blocks

ketone| alcohol

Aromatic Acetophenones & Derivatives (substituted)

Carbonyl Compounds

Ketones