trans-Dichlorodiamineplatinum(II)

Product Name: trans-Dichlorodiamineplatinum(II)
CAS No.: 14913-33-8
Chemical Name: trans-Dichlorodiamineplatinum(II)
Synonyms: CPDC;CIS-DDP;PLATINOL;PLATINEX;BRIPLATIN;CISPLATYL;CISMAPLAT;nsc131558;TRANS-DDP;NEOPLATIN
CBNumber: CB6236182
Molecular Formula: Cl2H4N2Pt
Formula Weight: 298.03
MOL File: 14913-33-8.mol

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trans-Dichlorodiamineplatinum(II) Property

Melting point:: 340 °C (dec.)(lit.)
storage temp.: 2-8°C
solubility: DMSO (Sparingly)
form: crystalline
color: yellow
Water Solubility: Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water.
Exposure limits: ACGIH: TWA 0.002 mg/m3
NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3
EPA Substance Registry System: Platinum, diamminedichloro-, (SP-4-1)- (14913-33-8)

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Safety

Hazard Codes: T,Xn
Risk Statements: 45-25-41-68-42/43-40-23/24/25
Safety Statements: 53-26-39-45-36/37-24-23
RIDADR: UN 3288 6.1/PG 2
WGK Germany: 3
RTECS: TP2455000
F: 10-21
HazardClass: 6.1(a)
PackingGroup: II
HS Code: 28439000
Hazardous Substances Data: 14913-33-8(Hazardous Substances Data)
Toxicity: mouse,LD50,intraperitoneal,27mg/kg (27mg/kg),Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H318Causes serious eye damage

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3252
Product name: Transplatin
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 50MG
Price: $576
Updated: 2024/03/01

Sigma-Aldrich

Product number: P1525
Product name: trans-Platinum(II)diammine dichloride
Packaging: 1g
Price: $323
Updated: 2024/03/01

Sigma-Aldrich

Product number: BP544
Product name: Transplatin
Purity: British Pharmacopoeia (BP) Reference Standard
Packaging: 25MG
Price: $266
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1672803
Product name: Transplatin
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $1490
Updated: 2024/03/01

Alfa Aesar

Product number: 010472
Product name: trans-Diamminedichloroplatinum(II), Pt 64.5% min
Packaging: 1g
Price: $211
Updated: 2024/03/01

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trans-Dichlorodiamineplatinum(II) Chemical Properties,Usage,Production

Chemical Properties

Yellow Powder or Crystal

Uses

Transplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.

Uses

Transplatin is the trans stereoisomer impurity of trans-Dichlorodiamineplatinum(II), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.

Definition

ChEBI: A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic.

Safety Profile

Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. See also PLATINUM COMPOUNDS. When heated to decomposition it emits toxic fumes of NOx and Cl-.

trans-Dichlorodiamineplatinum(II) Preparation Products And Raw materials

Raw materials

Preparation Products

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trans-Dichlorodiamineplatinum(II) Suppliers

Belgium 1 Canada 1 China 119 Germany 2 India 5 Japan 1 Switzerland 1 United Kingdom 4 United States 12 Global 146

Baoji Funuokang Industrial Co., Ltd

Tel: 13220096790
Email: 1754423088@qq.com
Country: China
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Nanjing JiuSiNuo Biopharmaceutical Technology Co., Ltd

Tel: 18851976882
Email: chensheng870628@126.com
Country: China
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J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Advantage: 62

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
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Energy Chemical

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Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
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Email: isenchem@163.com
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Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
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View Lastest Price from trans-Dichlorodiamineplatinum(II) manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: trans-Dichlorodiamineplatinum(II) 14913-33-8
Price: US $0.00/G
Min. Order: 10G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-08

Career Henan Chemical Co

Product: trans-Dichlorodiamineplatinum(II) 14913-33-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2019-08-31

14913-33-8, trans-Dichlorodiamineplatinum(II)Related Search:

trans,trans-2,4-Undecadienal Quinclorac Cobalt chloride Cisplatin Sodium dichloroisocyanurate Dichloroethane Thionyl chloride N,N-Dimethylacetamide Platinum tetrachloride CIS-DICHLOROBIS(PYRIDINE)PLATINUM(II) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Bis(benzonitrile)dichloroplatinum(II) TRIMETHYLBENZYLAMMONIUMHEXACHLOROPLATINATE (IV) Bis(ethylenediamine)platinum(II) chloride CIS-BIS(ACETONITRILE)DICHLOROPLATINUM(II) Tetraammineplatinum(II) chloride hydrate Tetraammineplatinum (II) chloride hydrate Ammonium chloroplatinate

trans-Diamminedichloroplatinum(II), Pt 64.5% min

trans-Diamminedichloroplatinum(II), trans-Dichlorodiammineplatinum(II)

Transplatin (25 mg)

trans-Dichlorodiamineplatinum(II)trans-DDPTransplatin

trans-DichlorodiaMineplatinuM(II), 99.95%, (trace Metal basis)

LEDERPLATIN

BRIPLATIN

DIAMMINEDICHLOROPLATINATE (II)

CIS-PLATINUM

CIS-PLATINUM(II)DIAMINE DIHYDROCHLORIDE

CIS-PLATINUM(II)DIAMMINE DICHLORIDE

CISPLATYL

CIS PT(NH3)2CL2

CISMAPLAT

CISPLATIIN

CISPLATIN DIHYDROCHLORIDE

CIS-DIAMMINEPLATINUM(II) DICHLORIDE

CIS-DICHLORODIAMINEPLATINUM(II)

CIS-DICHLORODIAMMINE PLATINUM[II]

CIS-DICHLORODIAMMINOPLATINUM

CIS-DDP

CIS-DIAMMINEPLATINUM (II) CHLORIDE

CIS-DIAMMINEDICHLOROPLATINUM(II)

CIS-DIAMMINEDICHLORPLATINE

CIS-DIAMINEDICHLOROPLATINUM

CIS-DIAMINODICHLOROPLATINUM

CPDC

trans-PlatinuMdiaMMine dichloride (II)

Trans-DiamMinedichloroplatinum(II), Pt Min

transplatin

trans-platinumdiamminedichloride

cisplatin bulk drug impurity A

trans-dichloro-diaminoplatinum (II)

TRANS-PLATINUM(II)DIAMMINE DICHLORIDE

diamminedichloro-platinu(sp-4-1)

dichlorodiamineplatinum(ii)

nsc131558

trans-diaminedichloroplatinum

trans-diamminedichloroplatinum

trans-dichlorodiammineplatinum

TRANS-DIAMMINEDICHLOROPLATINUM(II)

TRANS-DDP

trans-diammineplatinum(ii) dichloride

TRANS-DICHLORODIAMINEPLATINUM(II)

TRANS-DICHLORODIAMMINE-PLATINUM[II]

NEOPLATIN

PLATINUM DIAMMINO DICHLORIDE

PLATAMINE

PLATINOL

PLATINOXAN

PLATIBLASTIN

PLATINEX

TRANS-DIAMMINEDICHLOROPLATINUM(II), 99.99%

trans-Diamminedichloroplatinum(II), 99.9%

trans-Dichlorodiamineplatinum(II), 99.95%

trans-Dichlorodiammineplatinum(II),99%

TRANS-PLATINUM(II)DIAMINEDICHLORIDE

TRANS-DIAMINECHLOROPLATINUM(II)