ChemicalBook > CAS DataBase List > (+)-AJ 76 HYDROCHLORIDE

(+)-AJ 76 HYDROCHLORIDE

Product Name
(+)-AJ 76 HYDROCHLORIDE
CAS No.
85379-09-5
Chemical Name
(+)-AJ 76 HYDROCHLORIDE
Synonyms
AJ-76;U-80278A;(+)-AJ76 HCL;(+)-AJ 76 HYDROCHLORIDE;5-methoxy-1-methyl-2-(n-propylamino)tetralin;N-Propyl-1α-methyl-5-methoxytetralin-2α-amine;(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)-TETRALIN HCL;(1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinehydrochloride;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)TETRALIN HYDROCHLORIDE
CBNumber
CB6241438
Molecular Formula
C15H23NO
Formula Weight
233.35
MOL File
85379-09-5.mol
More
Less

(+)-AJ 76 HYDROCHLORIDE Property

Boiling point:
345.3±42.0 °C(Predicted)
Density 
1.00±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 10 mM in H2O
form 
White crystalline solid.
pka
10.28±0.40(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
A965323
Product name
AJ-76
Packaging
10mg
Price
$115
Updated
2021/12/16
ApexBio Technology
Product number
B6403
Product name
(+)-AJ76hydrochloride
Packaging
10mg
Price
$257
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009809
Product name
(+)-AJ 76 HYDROCHLORIDE
Purity
95.00%
Packaging
10MG
Price
$716.1
Updated
2021/12/16
ApexBio Technology
Product number
B6403
Product name
(+)-AJ76hydrochloride
Packaging
50mg
Price
$1083
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0009809
Product name
(+)-AJ 76 HYDROCHLORIDE
Purity
95.00%
Packaging
100MG
Price
$1686.3
Updated
2021/12/16
More
Less

(+)-AJ 76 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

(+)-AJ 76 Hydrochloride was used in asymmetric synthesis of methoxymethyl(di-n-propylamino)tetralin hydrochloride.

Definition

ChEBI: A secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 nd 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively).

Biological Activity

Dopamine receptor antagonist with preferential action at presynaptic receptors (pK i values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD 3 . hD 4 , hD 2S , hD 2L and rD 2 receptors respectively).

References

[1]. kullingsjö h, carlsson a, svensson k. effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-aj76, on locomotor activity and brain da metabolism in the rat. eur j pharmacol, 1991, 205(3): 241-246.
[2]. piercey mf, lum jt, hoffmann we, et al. antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-aj76 and (+)-uh232. brain res, 1992; 588(2): 217-222.
[3]. waters n, hansson l, löfberg l, et al. intracerebral infusion of (+)-aj76 and (+)-uh232: effects on dopamine release and metabolism in vivo. eur j pharmacol, 1994, 251(2-3): 181-190.

(+)-AJ 76 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(+)-AJ 76 HYDROCHLORIDE Suppliers

China 25 Germany 1 Japan 1 Switzerland 2 United Kingdom 2 United States 4 Global 35
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
BIOMOL INTERNATIONAL, LP
Tel
--
Fax
--
Email
info@biomol.com
Country
United States
ProdList
1499
Advantage
77

85379-09-5, (+)-AJ 76 HYDROCHLORIDERelated Search:

Vanoxerine dihydrochloride Clozapine REMOXIPRIDE HYDROCHLORIDE CLOTHIAPINE BTCP HCL Bromocriptine mesylate 2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol U-99194 MALEATE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride LE 300 (RS)-TRANS-7-HYDROXY-2-[N-PROPYL-N-(3'-IODO-2'-PROPENYL)AMINO]TETRALIN MALEATE (R)-2-AMINOTETRALIN (5-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE (R)-(+)-5-METHOXY 2-AMINOTETRALIN ((R)-5-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-PROPYL-AMINE HYDROCHLORIDE 2-PROPYLAMINO-5-METHOXYTETRALIN (+)-AJ 76 HYDROCHLORIDE (+)-UH 232 MALEATE

  • AJ-76
  • (+)-AJ76 HCL
  • (+)-AJ 76 HYDROCHLORIDE
  • (1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)-TETRALIN HCL
  • (1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)TETRALIN HYDROCHLORIDE
  • (1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinehydrochloride
  • 5-methoxy-1-methyl-2-(n-propylamino)tetralin
  • (1S)-1,2,3,4-Tetrahydro-5-methoxy-1α-methyl-N-propyl-2α-naphthalenamine
  • (1S,2R)-1,2,3,4-Tetrahydro-5-methoxy-1-methyl-N-propyl-2-naphthalenamine
  • N-Propyl-1α-methyl-5-methoxytetralin-2α-amine
  • U-80278A
  • (1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin
  • 2-Naphthalenamine, 1,2,3,4-tetrahydro-5-methoxy-1-methyl-N-propyl-, (1S,2R)-
  • (1S,2R)-5-methoxy-1-methyl-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine
  • 85379-09-5