(+)-AJ 76 HYDROCHLORIDE
- Product Name
- (+)-AJ 76 HYDROCHLORIDE
- CAS No.
- 85379-09-5
- Chemical Name
- (+)-AJ 76 HYDROCHLORIDE
- Synonyms
- AJ-76;U-80278A;(+)-AJ76 HCL;(+)-AJ 76 HYDROCHLORIDE;5-methoxy-1-methyl-2-(n-propylamino)tetralin;N-Propyl-1α-methyl-5-methoxytetralin-2α-amine;(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)-TETRALIN HCL;(1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralinehydrochloride;(1S,2R)-CIS-5-METHOXY-1-METHYL-2-(N-PROPYLAMINO)TETRALIN HYDROCHLORIDE
- CBNumber
- CB6241438
- Molecular Formula
- C15H23NO
- Formula Weight
- 233.35
- MOL File
- 85379-09-5.mol
(+)-AJ 76 HYDROCHLORIDE Property
- Boiling point:
- 345.3±42.0 °C(Predicted)
- Density
- 1.00±0.1 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- Soluble to 10 mM in H2O
- form
- White crystalline solid.
- pka
- 10.28±0.40(Predicted)
N-Bromosuccinimide Price
- Product number
- A965323
- Product name
- AJ-76
- Packaging
- 10mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- B6403
- Product name
- (+)-AJ76hydrochloride
- Packaging
- 10mg
- Price
- $257
- Updated
- 2021/12/16
- Product number
- API0009809
- Product name
- (+)-AJ 76 HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $716.1
- Updated
- 2021/12/16
- Product number
- B6403
- Product name
- (+)-AJ76hydrochloride
- Packaging
- 50mg
- Price
- $1083
- Updated
- 2021/12/16
- Product number
- API0009809
- Product name
- (+)-AJ 76 HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1686.3
- Updated
- 2021/12/16
(+)-AJ 76 HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
(+)-AJ 76 Hydrochloride was used in asymmetric synthesis of methoxymethyl(di-n-propylamino)tetralin hydrochloride.
Definition
ChEBI: A secondary amino compound that consists of tetralin bearing methyl, propylamino and methoxy groups at positions 1, 2 and 5 respectively. Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 nd 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively).
Biological Activity
Dopamine receptor antagonist with preferential action at presynaptic receptors (pK i values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD 3 . hD 4 , hD 2S , hD 2L and rD 2 receptors respectively).
References
[1]. kullingsjö h, carlsson a, svensson k. effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-aj76, on locomotor activity and brain da metabolism in the rat. eur j pharmacol, 1991, 205(3): 241-246.
[2]. piercey mf, lum jt, hoffmann we, et al. antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-aj76 and (+)-uh232. brain res, 1992; 588(2): 217-222.
[3]. waters n, hansson l, löfberg l, et al. intracerebral infusion of (+)-aj76 and (+)-uh232: effects on dopamine release and metabolism in vivo. eur j pharmacol, 1994, 251(2-3): 181-190.
(+)-AJ 76 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(+)-AJ 76 HYDROCHLORIDE Suppliers
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- Country
- United States
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